What's the difference between rejuvenate and senescence?

Rejuvenate


Definition:

  • (v. t.) To render young again.

Example Sentences:

  • (1) Similar infusions of young blood rejuvenated muscle tissue in older mice, boosting their strength and exercise endurance, according to another paper in Science.
  • (2) It’s not just the people who want a cleaner country; China’s leaders too have a vision for national rejuvenation — the “China dream”.
  • (3) "We are seeing huge changes, and we urgently need to rejuvenate the UK's energy infrastructure.
  • (4) Five years ago, as Brazilian waxes became more common, demand for labial plastic surgery increased, then for "vaginal rejuvenation", perhaps the creepiest of the rejuvenations.
  • (5) Incubation with inosine alone restored ATP levels of the aged erythrocytes to some extent, but did not result in morphological rejuvenation.
  • (6) The Nobel Laureate and ex-director of Fermilab, Leon Lederman, described superconductivity as "the elixir to rejuvenate accelerators and open new vistas to the future".
  • (7) The 50-year-old former record company assistant, who began his career at EMI, has delivered ratings success by rejuvenating the talent show format.
  • (8) In 1889 Brown-Séquard claimed that injections of testicular extract rejuvenated the elderly, and in 1893 he introduced organotherapy.
  • (9) Circulating levels of FSH, LH, prolactin (Prl), estradiol (E), and progesterone (P) were determined by RIA in four intact and four monkeys luteectomized (CLX) at parturition in order to a) characterize the patterns of these hormones during the puerperium, and b) examine a possible inhibitory role of the "rejuvenated" corpus luteum (CL) on the resumption of follicle growth post partum.
  • (10) Analysts were somewhat surprised that AOL has found a buyer because they believed Bebo would require large investment to rejuvenate and because it only has a meaningful presence in the UK & Ireland.
  • (11) In our experience, this technique offers certain advantages and has fewer complications than subperiosteal lifting, allowing natural and harmonious rejuvenation of the upper two-thirds of the face, leaving no sequelae other than the coronal scar which is concealed in the scalp.
  • (12) Red cells stored in SAGM medium for 42 days at +4 degrees C were rejuvenated by bicarbonate, pyruvate and adenosine.
  • (13) Although all three studies were done in mice, researchers believe a similar rejuvenating therapy should work in humans.
  • (14) They more often want to create great educational opportunities for all students but the system fails them by not allowing them to refresh, reinvigorate, rejuvenate and revitalise themselves and their teaching materials in meaningful ways.
  • (15) The advantages of proliferation as a means of repair are described and it is proposed that cell proliferation is required for full rejuvenation.
  • (16) She will also go head to head with another ITV export, James Goldston, who has been credited with rejuvenating ABC's Good Morning America, which has eclipsed NBC's Today from its longstanding position at number one in the breakfast ratings war.
  • (17) It would have been exceedingly harsh on the rejuvenated home team.
  • (18) He declared that he alone had the strength to secure the homeland and rejuvenate the economy in a 75-minute speech that pushed familiar buttons.
  • (19) This theory assumes that aging is due to the accumulation of multiple forms of molecular damage and that rejuvenation is due to repair.
  • (20) Submalar augmentation is a new approach that effectively deals with many of the problems encountered in midfacial rejuvenation.

Senescence


Definition:

  • (n.) The state of growing old; decay by time.

Example Sentences:

  • (1) The proliferation of this cell type may represent an escape from the senescence pathway and progression to immortal tumor cells.
  • (2) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
  • (3) In addition, we have shown that long-lived, presumably non-senescent, strains do not arise by suppressor mutation, but lose senescence plasmid DNA by another mechanism.
  • (4) Senescent (26-28 months) Fischer 344 rats were shown to have a lower density of D2 sites (-36%) without any change in affinity in membranes prepared from homogenized caudate-putamen (CPU), as compared to young adult (5-6 months) rats.
  • (5) The cell cycle-dependent changes in the transglutaminase mRNA levels strongly support the implicated involvement of the enzyme in cell growth, differentiation, and senescence.
  • (6) The increased levels of HK1 could affect other erythrocyte metabolic pathways slowing down the physiological rate of cellular senescence and result in increased activity levels of other cell-age-dependent enzymes.
  • (7) Advancing age was associated with a reduction in cell proliferative responses to PHA in both substrains, although the rate of decline was significantly more rapid in the senescence-prone animals.
  • (8) Instead of degenerative changes, these results show an activation of the vasopressinergic system in senescence and in SDAT patients, similar to earlier observations in the aged rat and in accordance with a rise in human neurophysin and VP levels reported recently.
  • (9) Thus, constitutive expression of specific cytochrome P450 genes is repressed or activated in senescent rats.
  • (10) Mild daily exercise, maintained throughout adult life into early senescence, attenuates muscle atrophy and promotes adaptive enzymatic changes in atrophying muscles.
  • (11) A second set of experiments which involved the injection of E2 into senescent male as well as female rats indicated that there were no sex differences in improvements in inclined screen performance, and that once the E2 injections were discontinued, performance returned to preadministration levels.
  • (12) Additionally, analysis of the multiple steps occurring in the El cultures, as well as in the emergence of the continuous cell lines, could potentially elucidate the processes occurring during human epithelial cell carcinogenesis and escape from senescence.
  • (13) Significant anamnestic SIgA responses were shown after oral immunization with DNP-BGG in adult rats, but was not observed in the senescent and midlife (10-12 months) rats.
  • (14) Modulation of cellular senescence by growth factors, hormones, and genetic manipulation is contrasted, but newer studies in oncogene involvement are omitted.
  • (15) Under the same conditions, PM from senescent mice generated 62% of the initial O2- produced in response to zymosan, and 45% in response to OZ.
  • (16) Untreated cells, or cells treated with MCA or TPA only, usually became senescent around 6-8 weeks after plating and died, but those treated with both MCA and TPA became immortalised and underwent transformation to a phenotype capable of growth in soft agar.
  • (17) Because immune senescence most profoundly affects T lymphocyte functions, we suspected that LIA production would decline with age.
  • (18) Abnormal granular structures, which stained positively with periodic acid-Schiff (PAS-positive granular structures; PGS), were observed in the brain of senescence accelerated mouse (SAM).
  • (19) In senescent females the number of small IMPs was decreased in the perikarya and dendritic shafts compared to young females while the number of large particles was increased in the outer leaflet of the membrane of dendritic shafts, reaching values similar to those observed in males.
  • (20) Our data suggest that the release of u-PA antigen by human macrovascular endothelial cells can be used as an indicator of cell senescence.

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