(v. t.) To place again; to restore to a former place, position, condition, or the like.
(v. t.) To refund; to repay; to restore; as, to replace a sum of money borrowed.
(v. t.) To supply or substitute an equivalent for; as, to replace a lost document.
(v. t.) To take the place of; to supply the want of; to fulfull the end or office of.
(v. t.) To put in a new or different place.
Example Sentences:
(1) Thyroid replacement led to resolution of both apnea and depression.
(2) This may be due to efficient replacement of Leu by Phe at CUC (and, probably, CUU) codons throughout the genome.
(3) The previous year, he claimed £1,415 for two new sofas, made two separate claims of £230 and £108 for new bed linen, charged £86 for a new kettle and kitchen utensils and made two separate claims, of £65 and £186, for replacement glasses and crockery.
(4) We recently demonstrated that functional change in SSI was possible simply by replacing the amino acid residue at the reactive P1 site (methionine 73) of SSI.
(5) Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11 residue is replaced by glutamate gamma-alkylesters.
(6) In fact, the addition of conditioned medium obtained by 48 hr preincubation of isolated monocytes with 10% PF-382 supernatant (M-CM2) or the concomitant addition of supernatant from PF-382 cells (PF-382-CM) and from unstimulated monocytes (M-CM1) are capable of fully replacing the presence of monocytes in the BFU-E assay.
(7) Major plasma metabolites of quazepam were 2-oxoquazepam (OQ), obtained by replacement of S by O,N-desalkyl-2-oxoquazepam (DOQ), and 3-hydroxy-2-oxoquazepam (HOQ) glucuronide.
(8) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(9) It was concluded that the detachment of the oxaloyl residue from oxaloacetate and its replacement by a proton proceed with inversion of configuration at the methylene group which becomes methyl during the hydrolysis.
(10) I f you haven’t got a family, you need that replaced in some way, that’s the most important thing you can do for someone in care,” says 24-year-old Chloe Juliette, herself a care leaver.
(11) It is an intriguing moment: the new culture secretary, Sajid Javid, who was brought in to replace Maria Miller last month, is something of an unknown quantity.
(12) Replacement of Na+ by K+ or Li+ did not alter uptake, whereas replacement of Cl- by HCO-3 or gluconate- reduced uptake by approximately 40%.
(13) He underwent a mitral and aortic valve replacement, followed by a complicated postoperative course.
(14) Substitution of NaCl in the extracellular medium by sucrose, LiCl, or Na2SO4 had no effect on glutamate stimulation of [3H]dopamine release; however, release was inhibited when NaCl was replaced by choline chloride or N-methyl-D-glucamine HCl.
(15) C. parasitica mutant strains deficient in the production of endothiapepsin (eapA-) were constructed using a gene-replacement strategy.
(16) Replacement of vinyl groups with bulkier substituents (hydroxyethyl or acetyl groups) decreases holoenzyme stability and catalytic activity.
(17) It became fully operational in 1975, replacing its predecessor the rubber bullet.
(18) The experimental results for protein preparations of calmodulin in which Ca2+ was isomorphically replaced by Tb3+ were obtained by a spectrometer working at the Institute of Nuclear Physics.
(19) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
(20) Ultrastructural study of the uterine lesion demonstrated smooth muscle cells with only a few "autophagic" facuoles to cells nearly replaced by lysosomes.
Surrogate
Definition:
(n.) A deputy; a delegate; a substitute.
(n.) The deputy of an ecclesiastical judge, most commonly of a bishop or his chancellor, especially a deputy who grants marriage licenses.
(n.) In some States of the United States, an officer who presides over the probate of wills and testaments and yield the settlement of estates.
(v. t.) To put in the place of another; to substitute.
Example Sentences:
(1) The results suggest that RPE cannot be used reliably as a surrogate for direct pulse measurement in exercise training of persons with acute dysvascular amputations.
(2) In each of the clinics I visit I ask how much the surrogates are paid.
(3) Now 7, Jackson said the boy, nicknamed Blanket as a baby, was his biological child born from a surrogate mother.
(4) Since AIDS-specific laboratory tests are not yet commercially available, laboratory diagnoses of AIDS or of the AIDS-related complex (ARC) are based on "surrogate markers".
(5) This issue boils down to the question whether the ballot sponsors are more like citizens with strong policy views about a law (who normally cannot defend a law in federal court) or, instead, surrogate public officials who can act as the state for purposes of this lawsuit when the state itself refuses to do so (who would be permitted to defend the law).
(6) Alanine aminotransferase (ALT) measurements in blood donors has been advocated as a surrogate test for non-A, non-B hepatitis.
(7) Britain's Department of Health and Social Security (DHSS) seems to have badly miscalculated in discounting the political necessity of immediately introducing legislation to ban surrogate parenthood arrangements.
(8) A significant idiotype repertoire is shared by anti-hydatid antibodies produced by different individuals of the same or different species, and anti-Id raised against those antibodies behave as surrogate antigens producing a normal primary and secondary response in animals of different species from that used to isolate the Id.
(9) The study also addresses the methodological problems of evaluating response as a surrogate end point and the relevance of this association to clinical decision making and the design of clinical trials.
(10) The surrogate allowed for the measurement of ligament force time response during a controlled impact.
(11) These results support the use of a-IdAb as potential surrogates of critical determinants for FMD vaccines.
(12) A low correlation was found between HCV antibody screening with EIA and surrogate testing.
(13) Bone-induced multinucleated cells have been suggested as surrogates for the study of osteoclastic lineage and function.
(14) The associations were practically eliminated after adjustment for the number of sexual partners and alcohol consumption, probably a surrogate for an unidentified life-style risk factor.
(15) It would seem impossible to determine an ethical framework for the practice of surrogate motherhood that does not impinge on the liberties of some or offend others.
(16) In Johnson v. Calvert, a surrogate mother in California failed to gain custody of the child she bore after gestating an embryo from the ovum and sperm of the couple who hired her.
(17) The potential application of MAb2s to serve as surrogate immunogens for conformational epitopes is substantiated by the results presented in this report.
(18) However, the surrogate respondent was able to answer 45 of 57 tested items with agreement greater than 80%.
(19) The majority of gestational carriers stated that they had considered becoming a traditional surrogate but felt they could not surrender a child that was genetically theirs.
(20) Stepwise logistic regression analyses on professional and personal background variables showed that gender was related, cross-nationally, to self-reported directiveness in counseling, with men more likely than women to regard directive approaches as appropriate, more likely to give advice about fetuses with low-burden disorders, and more likely to present either IVF with donor egg or surrogate motherhood as options.