(v. t.) To place again; to restore to a former place, position, condition, or the like.
(v. t.) To refund; to repay; to restore; as, to replace a sum of money borrowed.
(v. t.) To supply or substitute an equivalent for; as, to replace a lost document.
(v. t.) To take the place of; to supply the want of; to fulfull the end or office of.
(v. t.) To put in a new or different place.
Example Sentences:
(1) Thyroid replacement led to resolution of both apnea and depression.
(2) This may be due to efficient replacement of Leu by Phe at CUC (and, probably, CUU) codons throughout the genome.
(3) The previous year, he claimed £1,415 for two new sofas, made two separate claims of £230 and £108 for new bed linen, charged £86 for a new kettle and kitchen utensils and made two separate claims, of £65 and £186, for replacement glasses and crockery.
(4) We recently demonstrated that functional change in SSI was possible simply by replacing the amino acid residue at the reactive P1 site (methionine 73) of SSI.
(5) Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11 residue is replaced by glutamate gamma-alkylesters.
(6) In fact, the addition of conditioned medium obtained by 48 hr preincubation of isolated monocytes with 10% PF-382 supernatant (M-CM2) or the concomitant addition of supernatant from PF-382 cells (PF-382-CM) and from unstimulated monocytes (M-CM1) are capable of fully replacing the presence of monocytes in the BFU-E assay.
(7) Major plasma metabolites of quazepam were 2-oxoquazepam (OQ), obtained by replacement of S by O,N-desalkyl-2-oxoquazepam (DOQ), and 3-hydroxy-2-oxoquazepam (HOQ) glucuronide.
(8) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(9) It was concluded that the detachment of the oxaloyl residue from oxaloacetate and its replacement by a proton proceed with inversion of configuration at the methylene group which becomes methyl during the hydrolysis.
(10) I f you haven’t got a family, you need that replaced in some way, that’s the most important thing you can do for someone in care,” says 24-year-old Chloe Juliette, herself a care leaver.
(11) It is an intriguing moment: the new culture secretary, Sajid Javid, who was brought in to replace Maria Miller last month, is something of an unknown quantity.
(12) Replacement of Na+ by K+ or Li+ did not alter uptake, whereas replacement of Cl- by HCO-3 or gluconate- reduced uptake by approximately 40%.
(13) He underwent a mitral and aortic valve replacement, followed by a complicated postoperative course.
(14) Substitution of NaCl in the extracellular medium by sucrose, LiCl, or Na2SO4 had no effect on glutamate stimulation of [3H]dopamine release; however, release was inhibited when NaCl was replaced by choline chloride or N-methyl-D-glucamine HCl.
(15) C. parasitica mutant strains deficient in the production of endothiapepsin (eapA-) were constructed using a gene-replacement strategy.
(16) Replacement of vinyl groups with bulkier substituents (hydroxyethyl or acetyl groups) decreases holoenzyme stability and catalytic activity.
(17) It became fully operational in 1975, replacing its predecessor the rubber bullet.
(18) The experimental results for protein preparations of calmodulin in which Ca2+ was isomorphically replaced by Tb3+ were obtained by a spectrometer working at the Institute of Nuclear Physics.
(19) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
(20) Ultrastructural study of the uterine lesion demonstrated smooth muscle cells with only a few "autophagic" facuoles to cells nearly replaced by lysosomes.
Terminate
Definition:
(v. t.) To set a term or limit to; to form the extreme point or side of; to bound; to limit; as, to terminate a surface by a line.
(v. t.) To put an end to; to make to cease; as, to terminate an effort, or a controversy.
(v. t.) Hence, to put the finishing touch to; to bring to completion; to perfect.
(v. i.) To be limited in space by a point, line, or surface; to stop short; to end; to cease; as, the torrid zone terminates at the tropics.
(v. i.) To come to a limit in time; to end; to close.
Example Sentences:
(1) The amino acid sequence deduced from the nucleotide sequence contained both amino- and carboxyl-terminal sequences.
(2) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(3) We have examined the insertion of bovine 17 alpha-hydroxylase (P45017 alpha) into the endoplasmic reticulum of COS 1 cells to evaluate the functional role of its hydrophobic amino-terminal sequence and membrane insertion.
(4) The use of glucagon in double-contrast studies of the colon has been recommended for various reasons, one of which is to facilitate reflux of barium into the terminal ileum.
(5) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
(6) Plasma NPY correlated better with plasma norepinephrine than with epinephrine, indicating its origin from sympathetic nerve terminals.
(7) As a group, the three mammalian proteins resemble bovine serum conglutinin and behave as lectins with rather broad sugar specificities directed at certain non-reducing terminal N-acetylglucosamine, mannose, glucose and fucose residues, but with subtle differences in fine specificities.
(8) In the caudal spinal trigeminal nucleus (Vc), the collaterals of one half of the periodontium afferent fibers terminated mainly in lamina V at the rostral and middle levels of Vc.
(9) The amino-terminal region of a 70 kDa mitochondrial outer membrane protein of yeast and the presequence of cytochrome c1, an inner membrane protein exposed to the intermembrane space, are thought to be responsible for localizing the proteins in their final destinations after synthesis in the cytosol.
(10) The mtRF-1 could translate all of the known termination codons in the rat mitochondrial genome.
(11) However, none of the nerve terminals making synaptic contacts with glomus cells exhibited SP-like immunoreactivity.
(12) The B cell epitopes included regions of transition between the more hydropathic (including the N-terminal end of the F1 and F2 protein) and hydrophilic sequences.
(13) Somatostatin-like immunoreactivity has been found to occur in nerve terminals and fibres of the normal human skin using immunohistochemistry.
(14) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
(15) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(16) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(17) The earliest degenerative changes were seen in sensory and motor terminals at 20-24 h after the lesion.
(18) The terminal half-life averaged 12 h following intravenous and 15 h after oral administration.
(19) A retrospective study examined the reactions to the termination of pregnancy for fetal malformation and the follow up services that were available.
(20) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.