(v. t.) To place again; to restore to a former place, position, condition, or the like.
(v. t.) To refund; to repay; to restore; as, to replace a sum of money borrowed.
(v. t.) To supply or substitute an equivalent for; as, to replace a lost document.
(v. t.) To take the place of; to supply the want of; to fulfull the end or office of.
(v. t.) To put in a new or different place.
Example Sentences:
(1) Thyroid replacement led to resolution of both apnea and depression.
(2) This may be due to efficient replacement of Leu by Phe at CUC (and, probably, CUU) codons throughout the genome.
(3) The previous year, he claimed £1,415 for two new sofas, made two separate claims of £230 and £108 for new bed linen, charged £86 for a new kettle and kitchen utensils and made two separate claims, of £65 and £186, for replacement glasses and crockery.
(4) We recently demonstrated that functional change in SSI was possible simply by replacing the amino acid residue at the reactive P1 site (methionine 73) of SSI.
(5) Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11 residue is replaced by glutamate gamma-alkylesters.
(6) In fact, the addition of conditioned medium obtained by 48 hr preincubation of isolated monocytes with 10% PF-382 supernatant (M-CM2) or the concomitant addition of supernatant from PF-382 cells (PF-382-CM) and from unstimulated monocytes (M-CM1) are capable of fully replacing the presence of monocytes in the BFU-E assay.
(7) Major plasma metabolites of quazepam were 2-oxoquazepam (OQ), obtained by replacement of S by O,N-desalkyl-2-oxoquazepam (DOQ), and 3-hydroxy-2-oxoquazepam (HOQ) glucuronide.
(8) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(9) It was concluded that the detachment of the oxaloyl residue from oxaloacetate and its replacement by a proton proceed with inversion of configuration at the methylene group which becomes methyl during the hydrolysis.
(10) I f you haven’t got a family, you need that replaced in some way, that’s the most important thing you can do for someone in care,” says 24-year-old Chloe Juliette, herself a care leaver.
(11) It is an intriguing moment: the new culture secretary, Sajid Javid, who was brought in to replace Maria Miller last month, is something of an unknown quantity.
(12) Replacement of Na+ by K+ or Li+ did not alter uptake, whereas replacement of Cl- by HCO-3 or gluconate- reduced uptake by approximately 40%.
(13) He underwent a mitral and aortic valve replacement, followed by a complicated postoperative course.
(14) Substitution of NaCl in the extracellular medium by sucrose, LiCl, or Na2SO4 had no effect on glutamate stimulation of [3H]dopamine release; however, release was inhibited when NaCl was replaced by choline chloride or N-methyl-D-glucamine HCl.
(15) C. parasitica mutant strains deficient in the production of endothiapepsin (eapA-) were constructed using a gene-replacement strategy.
(16) Replacement of vinyl groups with bulkier substituents (hydroxyethyl or acetyl groups) decreases holoenzyme stability and catalytic activity.
(17) It became fully operational in 1975, replacing its predecessor the rubber bullet.
(18) The experimental results for protein preparations of calmodulin in which Ca2+ was isomorphically replaced by Tb3+ were obtained by a spectrometer working at the Institute of Nuclear Physics.
(19) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
(20) Ultrastructural study of the uterine lesion demonstrated smooth muscle cells with only a few "autophagic" facuoles to cells nearly replaced by lysosomes.
Truncate
Definition:
(v. t.) To cut off; to lop; to maim.
(a.) Appearing as if cut off at the tip; as, a truncate leaf or feather.
Example Sentences:
(1) The relative potencies compared to insulin-like growth factor 2 (IGF-2) in displacing [125I]IGF-2 from rat liver membranes were recombinant truncated IGF-1, 0.3% and recombinant IGF-1, 0.2%.
(2) When the transcriptional activity of these proteins was examined it was found that carboxyl-truncated Myb is more effective as a transcriptional activator than full-length or amino-truncated Myb.
(3) The vector is relatively small (6 kilobase pairs) and contains a portion of the L. seymouri alpha-tubulin gene positioned in-frame with a truncated neomycin phosphotransferase gene that confers resistance to the aminoglycoside G418.
(4) These plasmids allow expression of native or truncated forms of the enzyme and easy purification of the products.
(5) Both the intracellular and secreted forms of the mu chains were similarly truncated.
(6) A new alternative splice site was incidently found 81 nucleotide downstream of motif II in both normal and truncated 4.1 mRNA.
(7) The other chimeras accumulated in the plasma membrane, and truncated LEP100 was secreted.
(8) The main protein species produced from full-length and truncated forms of celE was around 40 kDa in size and had an N-terminal amino acid sequence corresponding to that derived for mature EGE from the nucleotide sequence; in addition, larger species of about 75 kDa, presumably corresponding to full-size EGE, were produced by E. coli containing the full-length celE gene.
(9) The truncated LuxR proteins showed little or no ability to activate transcription of luxICDABE, as indicated by using luminescence as a sensitive indicator of promoter strength in E. coli.
(10) The expression of keratin and differentiation markers was identical to that of normal keratinocytes, suggesting that psoriatic epidermal differentiation is not truncated in vitro as has been postulated to be the case in vivo.
(11) Actin also exhibited a clear dual wave pattern of transport that coincided well with that of tubulin, indicating that both actin and tubulin were the major components of both groups IV and V.(ABSTRACT TRUNCATED AT 250 WORDS)
(12) This truncated C8C8 ceramide was soluble in water (but was still able to cross cell membranes) and was utilized by the Golgi apparatus of living cells to produce water-soluble truncated phospholipids and glycolipids that were then secreted into the medium.
(13) Neither the source nor the role of this soluble, truncated form of the membrane receptor has been determined.
(14) It may differ from the Mr 35,000 form in glycosylation or carboxyl-terminal truncation.
(15) The low hormone binding affinities of the truncated receptors taken together with high affinity hormone binding to the N-terminal extension of the LH receptor indicate the existence of two or more contact points between the receptor and the hormone.
(16) We were unable to confirm the high frequency of truncated messages of 4.7R in RB tumors reported by Lee et al.
(17) A transformed cell line containing a truncated gag-abl-pol protein, p85, that lacks most of the FeLV pol sequences was obtained by transfection of NIH 3T3 mouse cells.
(18) The calmodulin-binding domain of the CYA 62 truncated enzyme was labeled with a cleavable radioactive photoaffinity cross-linker coupled to calmodulin.
(19) This truncated receptor, lacking a transmembrane domain, appears not to be expressed at the plasma membrane.
(20) A truncated anchor-minus form of the G2 glycoprotein was found to be secreted into the culture medium, but was retained in the Golgi complex when coexpressed with the G1 glycoprotein.