(a.) Capable or admitting of being put back into a place.
(a.) Admitting of having its place supplied by a like thing or an equivalent; as, the lost book is replaceable.
(a.) Capable of being replaced (by), or of being exchanged (for); as, the hydrogen of acids is replaceable by metals or by basic radicals.
Example Sentences:
(1) Thyroid replacement led to resolution of both apnea and depression.
(2) This may be due to efficient replacement of Leu by Phe at CUC (and, probably, CUU) codons throughout the genome.
(3) The previous year, he claimed £1,415 for two new sofas, made two separate claims of £230 and £108 for new bed linen, charged £86 for a new kettle and kitchen utensils and made two separate claims, of £65 and £186, for replacement glasses and crockery.
(4) We recently demonstrated that functional change in SSI was possible simply by replacing the amino acid residue at the reactive P1 site (methionine 73) of SSI.
(5) Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11 residue is replaced by glutamate gamma-alkylesters.
(6) In fact, the addition of conditioned medium obtained by 48 hr preincubation of isolated monocytes with 10% PF-382 supernatant (M-CM2) or the concomitant addition of supernatant from PF-382 cells (PF-382-CM) and from unstimulated monocytes (M-CM1) are capable of fully replacing the presence of monocytes in the BFU-E assay.
(7) Major plasma metabolites of quazepam were 2-oxoquazepam (OQ), obtained by replacement of S by O,N-desalkyl-2-oxoquazepam (DOQ), and 3-hydroxy-2-oxoquazepam (HOQ) glucuronide.
(8) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(9) It was concluded that the detachment of the oxaloyl residue from oxaloacetate and its replacement by a proton proceed with inversion of configuration at the methylene group which becomes methyl during the hydrolysis.
(10) I f you haven’t got a family, you need that replaced in some way, that’s the most important thing you can do for someone in care,” says 24-year-old Chloe Juliette, herself a care leaver.
(11) It is an intriguing moment: the new culture secretary, Sajid Javid, who was brought in to replace Maria Miller last month, is something of an unknown quantity.
(12) Replacement of Na+ by K+ or Li+ did not alter uptake, whereas replacement of Cl- by HCO-3 or gluconate- reduced uptake by approximately 40%.
(13) He underwent a mitral and aortic valve replacement, followed by a complicated postoperative course.
(14) Substitution of NaCl in the extracellular medium by sucrose, LiCl, or Na2SO4 had no effect on glutamate stimulation of [3H]dopamine release; however, release was inhibited when NaCl was replaced by choline chloride or N-methyl-D-glucamine HCl.
(15) C. parasitica mutant strains deficient in the production of endothiapepsin (eapA-) were constructed using a gene-replacement strategy.
(16) Replacement of vinyl groups with bulkier substituents (hydroxyethyl or acetyl groups) decreases holoenzyme stability and catalytic activity.
(17) It became fully operational in 1975, replacing its predecessor the rubber bullet.
(18) The experimental results for protein preparations of calmodulin in which Ca2+ was isomorphically replaced by Tb3+ were obtained by a spectrometer working at the Institute of Nuclear Physics.
(19) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
(20) Ultrastructural study of the uterine lesion demonstrated smooth muscle cells with only a few "autophagic" facuoles to cells nearly replaced by lysosomes.
Tribasic
Definition:
(a.) Capable of neutralizing three molecules of a monacid base, or their equivalent; having three hydrogen atoms capable of replacement by basic elements on radicals; -- said of certain acids; thus, citric acid is a tribasic acid.
Example Sentences:
(1) Stromelysin consists of three domains the amino terminal propeptide(s) domain contains the tribasic amino acid sequence RRK which is important in the proteolytic activation of this zymogen by trypsin-like serine proteases.
(2) Tribasic calcium phosphate was chosen as a model for solid bone samples, which are stained with doxorubicin in patients who have received long-term doxorubicin therapy.
(3) Four anhydrous composites--(1) tribasic calcium phosphate (TCP 50%) and triethylene glycol dimethacrylate (TEGDM), (2) silanated lithium aluminum silicate (SS, 75%) and TEGDM, (3) barium sulfate [BaSO4 (70%) and poly(methyl methacrylate) (PMMA)], and (4) silane-coated barium glass (SBG) (75%)--and PMMA were employed in the water-sorption studies at 37 degrees C. The effect of 5% 4-META on the diffusion and uptake of water was studied at 37 degrees C. The data conformed approximately to Fick's laws of diffusion.
(4) Subjects ingested either 1 gm of tribasic sodium phosphate or a glucose placebo four times daily for 3 days prior to performing either an incremental maximal cycling test or a simulated 40-km time trial on a computerized race simulator.
(5) Addition of tribasic magnesium phosphate [Mg3(PO4)2 X 8H2O] prevented the repression of cyclase and markedly stimulated cephalosporin production.
(6) The resulting mixture of chelated and unchelated nucleotides and tribasic acids effected coordinated control of citrate synthase, aconitase, isocitrate dehydrogenase, succinyl CoA synthetase, fumarase, and nucleoside diphosphokinase, because Mg2+-chelates are generally substrates whereas unchelated species are inhibitors.
(7) Our data have defined the cleavages for the signal peptide and propeptide and demonstrate that a tribasic sequence can be used to eliminate N-terminal heterogeneity in this molecule.
(8) Cleavage at a tribasic residue processing site generates a urotensin II with the primary structure: Ala-Gly-Thr-Thr-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Val.
(9) Calcium carbonate, and particularly tribasic calcium phosphate tablets, are not recommended for patients with achlorhydria.
(10) The rare disease of pulmonary alveolar microlithiasis is characterized by innumerable microscopic stones, mainly of tribasic calcium phosphate, within the pulmonary alveoli.
(11) A Langmuir adsorption isotherm at pH 7.4 and the maximum adsorption capacity of tribasic calcium phosphate were established.
(12) The adsorption of doxorubicin hydrochloride, a potent antitumor agent, on solid tribasic calcium phosphate was studied in vitro.
(13) Subjects ingested 1000 mg of tribasic sodium phosphate or a placebo four times daily for 6 d. A maximal running stress test or a 5-mile performance run was performed randomly on either the 3rd or the 6th d. Test sessions were separated by a 2-wk washout period and repeated with alternating phosphate and placebo regimens.
(14) Both forms of tribasic isocitrate, free and metal chelated are used as alternative substrates with different turnover and affinity.
(15) ATP analogues that dissociate only as far as the tribasic form were also able to inhibit channel activity.
(16) In addition, three sites were identified in the mature protein core of STC (two dibasic, one tribasic) that may be acted upon by endopeptidases to produce truncated forms of the hormone.
(17) One peptide equivalent to the previously reported C-terminal CgB (CCB) is released by processing at a tribasic segment.
(18) Hyroxyapatite (HOAp), tribasic calcium phosphate, crystals induced typical signs of inflammation when injected into the footpad of the rat.
(19) An additional derivative, containing the tribasic sequence from the human protein C propeptide preceding Ser+1, was secreted with full processing of the propeptide.
(20) The formation constant of the complex between cadmium and tribasic isocitrate varies from 860 M-1 at mu=0.16 to approximately 24,500 M-1 at infinite dilution.