(a.) Not enduring proof or trial; not of standard purity or fineness; disallowed; rejected.
(a.) Abandoned to punishment; hence, morally abandoned and lost; given up to vice; depraved.
(a.) Of or pertaining to one who is given up to wickedness; as, reprobate conduct.
(n.) One morally abandoned and lost.
(v. t.) To disapprove with detestation or marks of extreme dislike; to condemn as unworthy; to disallow; to reject.
(v. t.) To abandon to punishment without hope of pardon.
Example Sentences:
(1) The biotin and its attached streptavidin and radiolabel can be removed under mild conditions and the blot reprobed with a different antibody using an identical protocol.
(2) Replacing radioactively labeled probes by nonradioactive ones and detection by chemiluminescence instead of colorimetry allows a nonhazardous handling and offers the possibility of easily reprobing filters in Southwestern analysis.
(3) Repeated strippings and heterologous reprobings resulted in loss of target DNA from UV-immobilized nylon membranes as compared to baked nylon membranes.
(4) Thirty-three of sixty-one flies reprobed with an Endotrypanum probe were positive.
(5) The recurrent dacryocystocele was reprobed and the abnormality was resolved.
(6) DNA from the cDNA-positive cosmid clones was transferred to nylon filters and reprobed with cDNAs to identify restriction fragments that were expressed in these tissues.
(7) How did the Republican party allow that reprobate to hijack it?
(8) Northern blots reprobed with H1t-specific oligonucleotide showed that H1t mRNA remained prominent when TH2B mRNA started to decline after 8-12 days of coculture.
(9) A first technique allows to detect zinc- and DNA-binding proteins immobilized on the membrane; a second (a modification of Southern-Western blotting) makes it possible to detect DNA-binding proteins followed by immunological reprobing.
(10) He whips out his smartphone and records the scene, documenting the offence, and confronts the suspected reprobate with a voice which can boom across a street: “Hey!” California drought shaming takes on a class-conscious edge Read more Corcoran is a drought-shamer.
(11) New probes, based on sequence that lies beyond other restriction sites, are then synthesized, and the membranes are reprobed to reveal new sequence.
(12) Analysis with direct beta counting was also shown not to interfere with the successful reprobing of stripped dot blots with either unique sequence or total genomic probes.
(13) In the longer term the Conservatives only get away with supporting universal values like the rule of law and human rights while also condemning non-white foreigners, immigrants and benefit scroungers, because they are always silently whistling that none of the values we supposedly uphold apply to these reprobates.
(14) Many specimens among 37 other serum samples showed greater or lesser degrees of homology to different probes, as demonstrated by reprobing of samples fixed to nylon membranes.
(15) The hybridized nylon membranes could be stripped of probe and reprobed at least 6 times without loss of signal strength.
(16) These conceptions and their cultural influences incidentally inform us about one of the origins of the reprobation of onanism, as well as one possible way, among many others, for traditional thinking to explain the clinical enigma of depressive syndrome.
(17) (As told in the 1950 World Cup 'final' MBM from And Gazza Misses The Final , written by the excellent Rob Smyth and some other reprobate.)
(18) The Southern blots were reprobed with a cloned fragment of the STA2 glucoamylase gene of S. diastaticus.
(19) If the trailer is any indication , this final series will see the various gangsters and reprobates of the prohibition era attempting to legitimise themselves as businessmen.
(20) Repeated cycles of oligomer probe synthesis and subsequent reprobing permit rapid sequence walking along the genome.
Sinful
Definition:
(a.) Tainted with, or full of, sin; wicked; iniquitous; criminal; unholy; as, sinful men; sinful thoughts.
Example Sentences:
(1) Molsidomine and SIN-1 were tested in a thrombosis model in which thrombi are produced in small mesenteric vessels.
(2) These results support a hypothesis which proposes that ancestral SIN virus diverged into two distinct groups.
(3) Our studies show that SIN-1 and C87-3754 exert beneficial effects in a 6-h model of myocardial ischemia-reperfusion.
(4) Antibodies to all viruses were detected, and namely in these frequencies: SIN 0.9%, WN 16.9%, TAH 41.5%, CVO 23.1% and TBE 8.5%.
(5) As the later Spark might have said, a mortal sin against the commandment to love beauty wherever one may find it.
(6) The direct acting stimulants of soluble guanylate cyclase, sodium nitroprusside and SIN-1 (3-morpholino-sydnonimine), also increased the cGMP content of endothelial cells by 9.4 and 7.2 times, respectively.
(7) In superfused precontracted strips of rabbit aorta, methylene blue (MeB) or pyocyanin (Pyo, 1-hydroxy-5-methyl phenazinum betaine) at concentrations of 1-10 microM inhibited relaxations induced by endothelium-derived relaxing factor (EDRF), glyceryl trinitrate (GTN), S-nitroso-N-acetyl-penicillamine (SNAP) or 3-morpholino-sydnonimine (SIN-1).
(8) The likes of almond, blackberry and crocus first made way for analogue, block graph and celebrity in the Oxford Junior Dictionary in 2007, with protests at the time around the loss of a host of religious words such as bishop, saint and sin.
(9) These prostanoids were measured in platelets and endothelial cells alone or during their interaction, in the absence or presence of SIN-1.
(10) The haemodynamic effects of N-carboxy-3-morpholino-sydronimine-ethylester (molsidomine, SIN 10, Corvaton) were studied in anaesthetized mongrel dogs.
(11) The results indicated that both Sin B and Sal have inductive actions on drug metabolizing-phase I and phase II enzymes in mice and rats.
(12) Ten women with SIN were bilaterally salpingectomized.
(13) Analysis of the relationship between the pharmacodynamics and pharmacokinetics of SIN-1 suggests that an active metabolites is involved.
(14) The guanidine 3', 5'-cyclic monophosphate (cGMP) content (an index of EDRF production) was determined by radioimmunoassay under basal conditions and after acetylcholine (10(-5) M), bradykinin (10(-5) M) and SIN-1 (10(-4) M) stimulation.
(15) sin- mutants (defining six genes) were identified because they express HO in the absence of particular SWI products.
(16) We studied the effects of intracoronary injections of SIN-1 (0.8 mg), the active metabolite of molsidomine, on coronary artery diameters and coronary stenoses.
(17) Sessions included "naming the sin, lifting the shame" and "normal sinfulness or a sickness".
(18) The nitric oxide donor compound, 3-morpholinosydnonimine (SIN-1), was equipotent at relaxing the central and peripheral airways.
(19) Oxyhaemoglobin used for the assay of NO, inhibited the relaxation by SIN-1, but did not reduce vessel relaxations induced by GTN or iloprost, a stable prostacyclin analogue.
(20) A degraded SIN-1 solution that did not release NO was unable to block NMDA receptors.