(1) In summary, the present study of cortisol secretory dynamics in hypothyroid men has shown elevated mean 24-h serum concentrations of cortisol with preserved circadian rhymicity and normal endogenous production rates, but prolonged half-lives of cortisol disappearance.
(2) Although inv strains do exhibit some rhythmicity of their own, the rhythmicity apparently is not a direct result of the invertase deficiency, since there is no correlation between invertase level and rhymicity in 29 strains tested.
Thymic
Definition:
(a.) Of or pertaining to the thymus gland.
(a.) Pertaining to, or derived from, thyme; as, thymic acid.
Example Sentences:
(1) Marked enhancement of IFN-gamma production by T cells was seen in the presence of as little as 0.3% thymic DC.
(2) Trisomy 15 is a frequent chromosomal abnormality found in murine thymic tumors that develop spontaneously or by induction with irradiation, chemical carcinogens, or leukemogenic retroviruses.
(3) These data suggest that there are fundamental differences in the mechanisms of induction of virally and chemically induced thymic lymphomas in AKR mice.
(4) We document for the first time abnormal microenvironments in thymomas that may offer insights into understanding normal thymic differentiation.
(5) Obvious restitution of the thymic medulla was evident about 14 days after withdrawal of FK506.
(6) Thus, MHV infection inhibits spleen T-lymphocyte activation and blocks in vitro catecholamine and cAMP regulation of spleen T-cell activation but does not affect activation of thymic cells or spleen B cells.
(7) These data suggested that an inter-thymic exchange of cells did not occur during larval life.
(8) Although T cell tolerance to self antigens is primarily a reflection of clonal deletion in the thymus, recent evidence suggests that mature T cells are subject to negative regulation in the post-thymic environment: Extrathymic tolerance is the result of clonal anergy in some studies and T cell deletion in others.
(9) The recent identification among non-Hodgkin's malignant lymphomas of a high-grade malignancy entity of possible thymic origin and defined as lymphoblastic convoluted-cell lymphoma allowed the morphologic and radiological diagnosis of nine cases of this disease.
(10) Complex treatment with inclusion of thymalin resulted in an increase of the thymic factor, normalization of the lipid metabolism increase of the contractile function of the myocardium and, thus, increases the treatment efficacy.
(11) Furthermore, effector TH cells within the two compartments exert differential effector activities: splenic effector TH cells induce B cells to both proliferation and maturation, while thymic effector TH cells are defective in activating B-cell maturation.
(12) A murine model system was developed to determine whether ionizing radiation has a detrimental influence on thymic epithelium, cell function.
(13) Unlike previous studies with 13-cis-retinoic acid during the pre- and early organogenic stages of development (Hummler et al., Teratology 42:263-272, 1990), no thymic hypo- or aplasia or heart anomalies were observed, which may be attributable to the slightly longer 13-cis retinoic acid treatment period, i.e., GD 10-27.
(14) X-ray CT and MRI of the mediastinum showed images compatible with residual thymic tissue in 8 of 9 patients.
(15) Bilateral temporal epilepsies involving the limbic system on the one hand, bilateral frontal epilepsies on the other one, and P.M. status which may be paralleled, make these patients more susceptible to acute mental confusions, to acute thymic disorders, to delirious attacks.
(16) Thymulin activity was not altered throughout the study, suggesting that this thymic hormone cannot be used as a functional marker of short-term energy restriction.
(17) Four samples of thymoma obtained from patients affected by myasthenia gravis have been immunohistologically analysed on cryostat sections using a panel of antisera and monoclonal antibodies specific for antigens which define different stages of intrathymic lymphocyte differentiation and antigens specific for different types of thymic epithelial cells (cortical, medullary).
(18) In cultures of normal human thymic epithelium, we observed that the P19 protein was less expressed than in situ.
(19) In this study, thymic rosettes (TR), which are cell-cell complexes of thymic lymphocytes and stromal cells, were isolated from human thymic tissue, and were characterized.
(20) We do not yet know whether sex steroids modulate secretion of other thymic peptides.