(a.) Manifesting, exercising, or favoring rigor; allowing no abatement or mitigation; scrupulously accurate; exact; strict; severe; relentless; as, a rigorous officer of justice; a rigorous execution of law; a rigorous definition or demonstration.
(a.) Severe; intense; inclement; as, a rigorous winter.
(a.) Violent.
Example Sentences:
(1) He added: "There is a rigorous review process of applications submitted by the executive branch, spearheaded initially by five judicial branch lawyers who are national security experts and then by the judges, to ensure that the court's authorizations comport with what the applicable statutes authorize."
(2) Upon depletion of ATP in contraction, the P2 intensity reverted to the original rigor level, accompanied by development of rigor tension.
(3) which suggest that ~60-90% of the cross-bridges attached in rigor are attached in relaxed fibers at an ionic strength of 20 mM and ~2-10% of this number of cross-bridges are attached in a relaxed fiber at an ionic strength of 170 mM.
(4) The symptoms were successfully controlled by rigorous dietary measures.
(5) Rigorously designed clinical trials have demonstrated the efficacy and safety of fluoxetine in adults with major depressive disorder and obsessive-compulsive disorder (OCD) but not in patients below 18 years old.
(6) Unambiguous mapping and rigorous determination of the nature of the initiation triplet for IF2 beta, the smaller form of IF2, is critical for future mutagenesis of this codon, required for investigating the biological importance of both IF2 alpha and IF2 beta.
(7) The identification of the cDNA for an A2b-adenosine receptor will allow more rigorous characterization of its anatomical distribution and functional properties.
(8) Meanwhile, we need to show that the recent changes to how we work with the BBC Executive are allowing us to be more focused, more rigorous and more transparent in the work that we do, so that licence fee payers can get a better BBC.
(9) A village will be subject to rigorous evaluations in order to demonstrate sustainability and scalability, and that aid developed with an exit strategy can actually work.
(10) We therefore conclude that in postrigor muscles, paratropomyosin is released from the A-I junction region following the increase in the sarcoplasmic calcium ion concentration to 10(-4) M, and then binds to thin filaments, which results in weakening of rigor linkages formed between actin and myosin.
(11) New observations include: (1) In 15 nm cross sections that show single 14.5 nm levels: (a) The flared X structure characteristic of rigor is replaced by a straight-X figure in which the crossbridge density is aligned along the myosin-actin plane, rather than skewed across it as in rigor.
(12) Ferguson’s influence at Old Trafford has clearly waned since the Moyes appointment but, notably, there is no admission on his part that he chose the wrong man, insisting that the club followed a rigorous and methodical selection process.
(13) After a three-month period of rigorous training, two PAs were assigned to the ICU.
(14) Over the last few days a former member of parliament's intelligence and security committee, Lord King, a former director of GCHQ, Sir David Omand, and a former director general of MI5, Dame Stella Rimington, have questioned whether the agencies need to be more transparent and accept more rigorous scrutiny of their work.
(15) Even when carried out rigorously, culling does very little to help.
(16) Because the rigor of the present day "scientific method" demands clearcut and reproducible results and investigations require predictable performance of the parasite in an evenly maintained host that is in a highly constrained environment, we should not wonder why we cannot produce the events of nature.
(17) The best definition of osteoarthritis is anatomical, but to be rigorous must include the biochemical characteristics of osteoarthritis cartilage.
(18) "We remain committed to sourcing merchandise that is produced responsibly by suppliers that adhere to Walmart's rigorous Standards for Suppliers code of conduct."
(19) Edelman has a rigorous in-house carbon accounting system.
(20) Material, obtained by a rigorous three-stage sampling procedure from five normal rat livers, is systematically subjected to this analysis at four levels of magnification.
Stringency
Definition:
(n.) The quality or state of being stringent.
Example Sentences:
(1) Moreover, nick-translated [32-P]-pCS75, which is a pUC9 derivative containing a PstI insert with L and S subunit genes (for RuBisCO) from A. nidulans, hybridizes at very high stringency with restriction fragments from chromosomal DNA of untransformed and transformed cells as does the 32P-labeled PstI fragment itself.
(2) However, the tetM probe had a much lower sensitivity and required a lower stringency of hybridization.
(3) No homology was noted between the DNA of 10 tetracycline-resistant isolates of campylobacter and the streptococcal tetL, tetM, or tetN determinants when tested under conditions of high stringency.
(4) A procedure is provided to adjust the level of the 95th-percentile standard so that the stringency of the present standard is preserved.
(5) Eight of the lesions contained HPV DNA sequences, and in six of these the sequences were related to HPV 16 as deduced from low-stringency nucleic acid hybridization followed by low- and high-stringency washes.
(6) However, under conditions of low stringency, the DUG S and M RNA probes hybridised to the respective S and M segments of Ganjam (GAN) virus (another member of the NSD serogroup).
(7) Possibly due to the stringency of requirements for culturing such plasmacytomas, a highly advantageous combination of components was developed.
(8) When 3 to 5 stringency conditions were assayed on 4 frozen samples, similar results were obtained.
(9) At reduced stringency, a probe to the 3' HVR detects a new family of multiallelic loci that will be of value in the study of human genetics.
(10) This is consistent with the concept that stringency and inhibition of protein synthesis affect the rate of utilization rather than the synthesis of these ribonucleotide residues.
(11) To identify additional molecular forms of the exchanger, rat brain, heart, kidney, stomach, and spleen cDNA libraries were screened for their presence using an NHE-1 cDNA probe under low stringency hybridization conditions.
(12) By hybridization to a globin probe at reduced stringency all but four clones were found to contain small globin related inserts; two of these hybridized to hamster repetitive sequences as shown by Southern blot analysis.
(13) Structural homology to the P-450b gene was confirmed by comparative restriction mapping and high stringency hybridization of gene IV fragments to probes comprising the entire cDNA for P-450b.
(14) With this method, clear results were obtained under both normal and low stringency conditions, allowing hybridization between molecules sharing 80-85% and 60-65% identity, respectively.
(15) Hybridization of a bovine ARF 2 cDNA under low stringency with mammalian poly(A)+ RNA resulted in multiple bands that were subsequently assigned to the known ARF genes using ARF-specific oligonucleotide probes.
(16) However, consensus restriction maps of the two subgroups are largely dissimilar and, except at low stringencies, cross reassociation is readily detected only at restriction fragments from a particular conserved internal segment.
(17) Here we describe the isolation and characterization of a cDNA coding for the MR, from a rat hippocampus cDNA library, by low stringency hybridization to radiolabeled human glucocorticoid receptor cDNA.
(18) At higher stringency, human papillomaviruses cross-hybridized with each other reflecting species-specific similarities.
(19) irradiation before hybridization with mixed viral DNA probes under both low- and high-stringency conditions.
(20) The method is based on the priming of polymerase chain reaction (PCR) by an oligonucleotide complementary to the DNA sequence containing the mutation of interest, which anneals only to the perfectly matched sequence under high stringency conditions.