(v. t.) To cause to sound, especially by striking, as a metallic body; as, to ring a bell.
(v. t.) To make (a sound), as by ringing a bell; to sound.
(v. t.) To repeat often, loudly, or earnestly.
(v. i.) To sound, as a bell or other sonorous body, particularly a metallic one.
(v. i.) To practice making music with bells.
(v. i.) To sound loud; to resound; to be filled with a ringing or reverberating sound.
(v. i.) To continue to sound or vibrate; to resound.
(v. i.) To be filled with report or talk; as, the whole town rings with his fame.
(n.) A sound; especially, the sound of vibrating metals; as, the ring of a bell.
(n.) Any loud sound; the sound of numerous voices; a sound continued, repeated, or reverberated.
(n.) A chime, or set of bells harmonically tuned.
(n.) A circle, or a circular line, or anything in the form of a circular line or hoop.
(n.) Specifically, a circular ornament of gold or other precious material worn on the finger, or attached to the ear, the nose, or some other part of the person; as, a wedding ring.
(n.) A circular area in which races are or run or other sports are performed; an arena.
(n.) An inclosed space in which pugilists fight; hence, figuratively, prize fighting.
(n.) A circular group of persons.
(n.) The plane figure included between the circumferences of two concentric circles.
(n.) The solid generated by the revolution of a circle, or other figure, about an exterior straight line (as an axis) lying in the same plane as the circle or other figure.
(n.) An instrument, formerly used for taking the sun's altitude, consisting of a brass ring suspended by a swivel, with a hole at one side through which a solar ray entering indicated the altitude on the graduated inner surface opposite.
(n.) An elastic band partly or wholly encircling the spore cases of ferns. See Illust. of Sporangium.
(n.) A clique; an exclusive combination of persons for a selfish purpose, as to control the market, distribute offices, obtain contracts, etc.
(v. t.) To surround with a ring, or as with a ring; to encircle.
(v. t.) To make a ring around by cutting away the bark; to girdle; as, to ring branches or roots.
(v. t.) To fit with a ring or with rings, as the fingers, or a swine's snout.
(v. i.) To rise in the air spirally.
Example Sentences:
(1) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(2) Sterile, pruritic papules and papulopustules that formed annular rings developed on the back of a 58-year-old woman.
(3) The teeth were embedded in phenolic rings with acrylic resin.
(4) Surgical removal was avoided without complications by detaching it with a ring stripper.
(5) The Labour MP urged David Cameron to guarantee that officers who give evidence over the alleged paedophile ring in Westminster will not be prosecuted.
(6) These results coupled with previous studies support activation of benz[j]aceanthrylene via both 2 and cyclopenta ring epoxidation.
(7) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(8) Endothelium-dependent relaxations to acetylcholine and endothelium-independent relaxations to nitric oxide were observed in rings from both strains during contraction with endothelin.
(9) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
(10) The intracellular distribution and interaction of 19S ring-type particles from D. melanogaster have been analysed.
(11) Rings of isolated coronary and femoral arteries (without endothelium) were suspended for isometric tension recording in organ chambers filled with modified Krebs-Ringer bicarbonate solution.
(12) In all cases Richter's hernia was at the internal inguinal ring.
(13) Seventy-five hands showed normal distal latency, in which cases, however, the SNCV of the ring finger was always outside the normal range, while the SNCVs of the thumb, index and middle fingers were abnormal in 64%, 80% and 92% of cases respectively.
(14) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(15) Defects in the posterior one-half of the trachea, up to 5 rings long, were repaired, with minimal stenosis.
(16) A new analog of salmon calcitonin (N alpha-propionyl Di-Ala1,7,des-Leu19 sCT; RG-12851; here termed CTR), which lacks the ring structure of native calcitonin, was tested for biological activity in several in vitro and in vivo assay systems.
(17) The chemical shift changes observed on the binding of trimethoprim to dihydrofolate reductase are interpreted in terms of the ring-current shift contributions from the two aromatic rings of trimethoprim and from that of phenylalanine-30.
(18) Three strains of fluorescent pseudomonads (IS-1, IS-2, and IS-3) isolated from potato underground stems with roots showed in vitro antibiosis against 30 strains of the ring rot bacterium Clavibacter michiganensis subsp.
(19) Both adiphenine.HCl and proadifen.HCl form more stable complexes, suggesting that hydrogen bonding to the carbonyl oxygen by the hydroxyl-group on the rim of the CD ring could be an important contributor to the complexation.
(20) Serial sections from over a hundred such structures show that these are tubular structures and that the 'test-tube and ring-shaped' forms described in the literature are no more than profiles one expects to see when a tubular structure is sectioned.
Thiophene
Definition:
(n.) A sulphur hydrocarbon, C4H4S, analogous to furfuran and benzene, and acting as the base of a large number of substances which closely resemble the corresponding aromatic derivatives.
Example Sentences:
(1) Quantitative structure activity relationships of 2-amino-3-carboxylic acid ethyl ester thiophene derivatives are described.
(2) Some of the thiophenes and their acetylenic derivatives possess extremely potent phototoxic activities toward membrane-containing viruses.
(3) The compounds were obtained by condensation of appropriate hydrazines with thiophene 2-carboxaldehyde (series 1), thiophene 3-carboxaldehyde (series 2), and 5-nitrothiophene-2-carboxaldehyde (series 3).
(4) The prototype kappa-selective agonist, PD117302 (trans-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzo[b]thiophene-4- acetamide, 2) has been regio- and stereoselectively substituted in the C-4 and C-5 positions of the cyclohexyl ring with the methyl ether and spiro tetrahydrofuran groups.
(5) Since no previously identified genes involved in thiophene metabolism are located in this region, we designated the gene for the 48-kDa protein as thdF.
(6) Among the compounds described are 6-hydroxybenzo[b]thiophene-2-sulfonamide (16) and its acetate ester (23), which are among the most potent ocular hypotensive agents in this class, as assessed in the alpha-chymotrypsinized rabbit.
(7) The normalizing effects of the thiophene compounds on serum phosphorus levels were not significant at the dosages used.
(8) Maximum photo-basophil-histamine-release was 4% with acetylsalicylic acid, 10% with benoxaprofen, 20% with thiophene, 28% with diclofenac, 39% with tiaprofenic acid, 40% with carprofen, 55% with ketoprofen, and not demonstrable with indoprofen.
(9) The more hydrophobic cephalosporins, with a thiophene moiety at the C7 position, were more active than C7-methoxyiminoaminothiazole derivatives against S. aureus H (beta-lactam-susceptible), and compounds with a thioether function at C3 were more active than those with a sulphonyl function at this position.
(10) Several guanidine compounds were synthesized by the reaction of acid chlorides of thiophene and furan with guanidines.
(11) Alpha-terthienyl (alpha-T), a phototoxic thiophene compound isolated from marigolds (Tagetes species), affects cell membranes and does not appear to induce cytogenetic damage.
(12) In a directed search for the best compounds for clinical evaluation, some 150 selected nitroaromatic compounds, representing 6 distinct types, namely, furans, thiophenes, imidazoles, pyrazoles, pyrroles, and triazoles, have been synthesized and tested as hypoxic cell radiosensitisers and bioreductive drugs.
(13) Replacement of ring A by heterocyclic rings (thiophene or pyridine) leads to analogues with only moderate activity.
(14) These results clearly show that all three thiophene systems have potent activity as antihypertensive agents and that 3 and 4 are more potent than 1 or 2 as alpha 1-antagonists in vivo.
(15) A comparative study of the intestinal transport of DL-tryptophan and its 1-methylindole (tryptophan-l-Me) and benzo[b]thiophene (tryptophan-S) analogs has been carried out in vitro, using the everted intestinal sac of the rat and hamster.
(16) Except for cardioselectivity at low doses, the thiophenic analogue of metoprolol behaves in a very similar way as this compound in all the aspects considered in a preliminary pharmacological study.
(17) Six-month chronic oral toxicity studies of 7-chloro-3-[1-(2, 4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy-methyl] benzo[b]thiophene (sertaconazole, FI-7045, CAS 99592-32-2) were carried out in rats and ferrets.
(18) N-(3-dimethylaminopropyl)naphtho[2,1-b]thiophene-4-carboxamide and the 6-substituted methoxy, methyl, fluoro, chloro, bromo, trifluoromethyl, and cyano derivatives have been shown to bind to DNA via intercalation with binding constants in the 35-900 X 10(3) range at 25 degrees C, pH 7, and [Na+] = 0.019M.
(19) Tienilic acid (TA) is metabolized by human liver microsomes in the presence of NADPH with the major formation of 5-hydroxytienilic acid (5-OHTA) which is derived from the hydroxylation of the thiophene ring of TA.
(20) The synthesis of 1-substituted benzothieno[2,3-d]imidazoles and their most suitable synthesis precursor 2-nitro-3-substituted-amino benzo[b]thiophenes is reported.