(n.) A part, or character, performed by an actor in a drama; hence, a part of function taken or assumed by any one; as, he has now taken the role of philanthropist.
Example Sentences:
(1) The role of the family practitioner in antenatal care is discussed.
(2) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(3) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(4) In this study, the role of psychological make-up was assessed as a risk factor in the etiology of vasospasm in variant angina (VA) using the Cornell Medical Index (CMI).
(5) The role of Ca2+ in cell agglutination may be either to activate the cell-surface dextran receptor or to form specific intercellular Ca2+ bridges.
(6) The role of whole Mycobacteria, mycobacterial cell walls and waxes D as immunostimulants was well established many years ago.
(7) We have investigated a physiological role of endogenous insulin on exocrine pancreatic secretion stimulated by a liquid meal as well as exogenous secretin and cholecystokinin octapeptide (CCK-8) in conscious rats.
(8) The data indicate that ebselen is likely to be useful in the therapy of inflammatory conditions in which reactive oxygen species, such as peroxides, play an aetiological role.
(9) We have examined the insertion of bovine 17 alpha-hydroxylase (P45017 alpha) into the endoplasmic reticulum of COS 1 cells to evaluate the functional role of its hydrophobic amino-terminal sequence and membrane insertion.
(10) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(11) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(12) Although antihistamines are widely used for symptomatic treatment of seasonal (allergic) rhinitis, the role of histamines in the pathogenesis of infectious rhinitis is not clear.
(13) Because many wnt genes are also expressed in the lung, we have examined whether the wnt family member wnt-2 (irp) plays a role in lung development.
(14) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(15) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
(16) A possible role for mitochondria in myocardial adenosine production is discussed.
(17) Further studies are required to elucidate specific roles of the steroid-induced proteins in the effects of glucocorticoids on HTM and HS cells.
(18) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
(19) The manufacturers, British Aerospace describe it as a "single-seat, radar equipped, lightweight, multi-role combat aircraft, providing comprehensive air defence and ground attack capability".
(20) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
Use
Definition:
(v. t.) The act of employing anything, or of applying it to one's service; the state of being so employed or applied; application; employment; conversion to some purpose; as, the use of a pen in writing; his machines are in general use.
(v. t.) Occasion or need to employ; necessity; as, to have no further use for a book.
(v. t.) Yielding of service; advantage derived; capability of being used; usefulness; utility.
(v. t.) Continued or repeated practice; customary employment; usage; custom; manner; habit.
(v. t.) Common occurrence; ordinary experience.
(v. t.) The special form of ritual adopted for use in any diocese; as, the Sarum, or Canterbury, use; the Hereford use; the York use; the Roman use; etc.
(v. t.) The premium paid for the possession and employment of borrowed money; interest; usury.
(v. t.) The benefit or profit of lands and tenements. Use imports a trust and confidence reposed in a man for the holding of lands. He to whose use or benefit the trust is intended shall enjoy the profits. An estate is granted and limited to A for the use of B.
(v. t.) A stab of iron welded to the side of a forging, as a shaft, near the end, and afterward drawn down, by hammering, so as to lengthen the forging.
(v. t.) To make use of; to convert to one's service; to avail one's self of; to employ; to put a purpose; as, to use a plow; to use a chair; to use time; to use flour for food; to use water for irrigation.
(v. t.) To behave toward; to act with regard to; to treat; as, to use a beast cruelly.
(v. t.) To practice customarily; to make a practice of; as, to use diligence in business.
(v. t.) To accustom; to habituate; to render familiar by practice; to inure; -- employed chiefly in the passive participle; as, men used to cold and hunger; soldiers used to hardships and danger.
(v. i.) To be wont or accustomed; to be in the habit or practice; as, he used to ride daily; -- now disused in the present tense, perhaps because of the similarity in sound, between "use to," and "used to."
(v. i.) To be accustomed to go; to frequent; to inhabit; to dwell; -- sometimes followed by of.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(3) Therefore, these findings may extend the use of platelets as neuronal models.
(4) All transplants were performed using standard techniques, the operation for the two groups differing only as described above.
(5) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(6) It was tested for recovery and separation from other selenium moieties present in urine using both in vivo-labeled rat urine and human urine spiked with unlabeled TMSe.
(7) A study revealed that the percentage of active sperm in semen 30 seconds after ejaculation was 10.3% when a nonoxynol 9 latex condom was used as opposed to 55.9% in a nonspermicidal condom.
(8) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(9) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(10) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(11) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
(12) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(13) Questionnaires were used and the respondent self-designation method measured leadership.
(14) At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent.
(15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(16) Use of the improved operative technique contributed to reduction in number of complications.
(17) Down and up regulation by peptides may be useful for treatment of cough and prevention of aspiration pneumonia.
(18) Our data suggest that a rational use of surveillance cultures and serological tests may aid in an earlier diagnosis of FI in BMT patients.
(19) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(20) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.