(n.) Having inequalities, small ridges, or points, on the surface; not smooth or plain; as, a rough board; a rough stone; rough cloth.
(n.) Not level; having a broken surface; uneven; -- said of a piece of land, or of a road.
(n.) Not polished; uncut; -- said of a gem; as, a rough diamond.
(n.) Tossed in waves; boisterous; high; -- said of a sea or other piece of water.
(n.) Marked by coarseness; shaggy; ragged; disordered; -- said of dress, appearance, or the like; as, a rough coat.
(n.) Hence, figuratively, lacking refinement, gentleness, or polish.
(n.) Not courteous or kind; harsh; rude; uncivil; as, a rough temper.
(n.) Marked by severity or violence; harsh; hard; as, rough measures or actions.
(n.) Loud and hoarse; offensive to the ear; harsh; grating; -- said of sound, voice, and the like; as, a rough tone; rough numbers.
(n.) Austere; harsh to the taste; as, rough wine.
(n.) Tempestuous; boisterous; stormy; as, rough weather; a rough day.
(n.) Hastily or carelessly done; wanting finish; incomplete; as, a rough estimate; a rough draught.
(n.) Produced offhand.
(n.) Boisterous weather.
(n.) A rude fellow; a coarse bully; a rowdy.
(adv.) In a rough manner; rudely; roughly.
(v. t.) To render rough; to roughen.
(v. t.) To break in, as a horse, especially for military purposes.
(v. t.) To cut or make in a hasty, rough manner; -- with out; as, to rough out a carving, a sketch.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.
Rude
Definition:
(superl.) Characterized by roughness; umpolished; raw; lacking delicacy or refinement; coarse.
(superl.) Unformed by taste or skill; not nicely finished; not smoothed or polished; -- said especially of material things; as, rude workmanship.
(superl.) Of untaught manners; unpolished; of low rank; uncivil; clownish; ignorant; raw; unskillful; -- said of persons, or of conduct, skill, and the like.
(superl.) Violent; tumultuous; boisterous; inclement; harsh; severe; -- said of the weather, of storms, and the like; as, the rude winter.
(superl.) Barbarous; fierce; bloody; impetuous; -- said of war, conflict, and the like; as, the rude shock of armies.
(superl.) Not finished or complete; inelegant; lacking chasteness or elegance; not in good taste; unsatisfactory in mode of treatment; -- said of literature, language, style, and the like.
Example Sentences:
(1) You need a little moleskine, to write rude ideas... Mel No, I’ve just started recycling them.
(2) I categorically never said that ‘Britain has so many paedophiles because it has so many Asian men’.” She added that it was “totally untrue” that she had threatened to “take this inquiry down with me”, and absolutely rejected being rude and abusive to junior staff.
(3) For a while yesterday, Hazel Blears's selfishly-timed resignation with her rude "rock the boat" brooch send shudders of revulsion through some in the party.
(4) Like low blood pressure after a heart attack, then, cheap oil should arguably be regarded not as a sign of rude health, but rather as a consequence of malaise.
(5) This country has had a free press for the last 300 years, that has been irreverent and rude as my website is and holding public officials to account.
(6) We had some memorable encounters and he was very rude to me.
(7) He privately told the privy counsellors' committee of inquiry set up to review the events leading up to the invasion: "If I may be very frank and rather rude, you had to keep the ball in the air with the Argentines.
(8) There will be dialogue and discussions about what works, rather than rude surprises that backfire.
(9) As Google states, it is definitely in the company’s best interest to get its first smartglass customers to behave, as “breaking the rules or being rude will not get businesses excited about Glass and will ruin it for other Explorers”.
(10) I think, in all honestly, if I could be Bradley Whitford I would be very, very happy.” He becomes almost drawlingly dreamy, rolling his “r”s as he leans against the warm oolite cliffs of this Jurassic Coast, until rudely interrupted by me, asking whether there’s talk of a Broadchurch 3 .
(11) If someone was rude to you, you were rude back to them.
(12) Brexiters face rude awakening on immigration, says ex-minister Read more The problem is, there is nothing on the horizon to suggest that achieving any significant reduction in immigration is achievable or even desirable.
(13) He repeatedly argued that his south London upbringing meant he was rude to people who were rude to him and said Jones needed to “get over it”, although he said that he was unaware of his colleague’s history of illness.
(14) When he sees what he's inherited, he may get a rude awakening.
(15) Having reassured ourselves that we’re justified in “holding them to account” and “having robust debates” and “speaking truth to power”, we’re now just flat-out rude to their faces?
(16) But the fact that there is a serious disagreement between Zimbabwe and the United Kingdom does not mean that you should then be discourteous or rude."
(17) I said to them afterwards: ‘If you’re not on it 100% in this league, you’ll get a rude awakening.’’” Albion must be sick of the sight of QPR and Charlie Austin in particular.
(18) I can think of hordes of politicians who look worse and "weirder", with wet little pouty-mouths, strange shiny skin, mad glaring eyes, deathly pale demeanour, blank gaze and an unhealthy quantity of fat (I can't name them, because it's rude to make personal remarks), and I don't hear anyone calling them "weird", or mocking their looks, except for the odd bold cartoonist, but when it comes to Miliband , it's be-as-rude-as-you-like time.
(19) She said something rude, and I picked up her arm and I bit it!
(20) So instead of asking for anything on her birthday, she gives her friends presents, and she regularly sticks bullies and rude policemen in trees.