(n.) Having inequalities, small ridges, or points, on the surface; not smooth or plain; as, a rough board; a rough stone; rough cloth.
(n.) Not level; having a broken surface; uneven; -- said of a piece of land, or of a road.
(n.) Not polished; uncut; -- said of a gem; as, a rough diamond.
(n.) Tossed in waves; boisterous; high; -- said of a sea or other piece of water.
(n.) Marked by coarseness; shaggy; ragged; disordered; -- said of dress, appearance, or the like; as, a rough coat.
(n.) Hence, figuratively, lacking refinement, gentleness, or polish.
(n.) Not courteous or kind; harsh; rude; uncivil; as, a rough temper.
(n.) Marked by severity or violence; harsh; hard; as, rough measures or actions.
(n.) Loud and hoarse; offensive to the ear; harsh; grating; -- said of sound, voice, and the like; as, a rough tone; rough numbers.
(n.) Austere; harsh to the taste; as, rough wine.
(n.) Tempestuous; boisterous; stormy; as, rough weather; a rough day.
(n.) Hastily or carelessly done; wanting finish; incomplete; as, a rough estimate; a rough draught.
(n.) Produced offhand.
(n.) Boisterous weather.
(n.) A rude fellow; a coarse bully; a rowdy.
(adv.) In a rough manner; rudely; roughly.
(v. t.) To render rough; to roughen.
(v. t.) To break in, as a horse, especially for military purposes.
(v. t.) To cut or make in a hasty, rough manner; -- with out; as, to rough out a carving, a sketch.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.
Scratchy
Definition:
(a.) Characterized by scratches.
Example Sentences:
(1) That cameo seemed horribly emblematic of a thoroughly underwhelming opening half which ended unadorned by a single shot on target, but almost imperceptibly something was shifting, and Klopp’s demeanour slowly shifted from jovially laid-back to scratchy and irritable.
(2) All round Europe there have been political earthquakes in a volatile anti-politics age: the surprise is that Britain’s scratchy, irascible electorate hasn’t expressed its underlying anger that ordinary people paid the price for the bankers’ crash.
(3) Joseph Morpurgo's solo hour starts with scratchy old American TV footage.
(4) But as expected, the scratchy blankets are covered in hairs, the food is poor and the bathroom horrible (we queue to clean our teeth at the one working tap while a man washes his feet at it).
(5) And they took me into a theatre, and I saw this scratchy, black and white duke with no sound and a terrible track and all this camera noise of a movie that lasted three and a half hours at that time or something, and everybody was speaking a different language.
(6) Hard and scratchy foods also are consumed frequently.
(7) By setting aside the past, this was the day Miliband took full command of his party, a shadow cabinet behind him no longer scratchy with a few doubters.
(8) Dryness was reported more frequently than the symptoms scratchy and watery (p less than 0.001).
(9) Three months later, Stern was holding a conference call with reporters on a scratchy phone line from Havana.
(10) In a scratchy first half it took 25 minutes for Argentina to create a chance, Higuaín heading over from Messi’s whipped free-kick, but it was the Swiss who had the better opening two minutes later, Granit Xhaka shooting low but straight at Sergio Romero from a Shaqiri cutback.
(11) In his scratchy address, the then-head of News Corp in Europe and Asia laid into the BBCarguing: "The scope of its activities and ambitions is chilling."
(12) One aspect of England's scratchy record in World Cup penalty shoot-outs since they won the trophy in 1966 perhaps doesn't require a knowledge of high-level mathematics.
(13) What has been happening in West Everton this morning – this scritchy-scratchy Vivaldi – is more than just a music workshop.
(14) Serosis, sweating, scratchy clothes, allergy, infection, scratching, allergic contact dermatitis, anxiety, and coexisting disease are potential flare factors.
(15) Mourinho spoke about the importance of practising the transitions from attack to defence and defence to attack, and introduced to public consciousness the concept of “resting on the ball”, passing it around at the back to give players time to recuperate, but his football was scratchy and, frankly, a little dull.
(16) He even says "I'm killing indie rap" at one point, and it's true: with his mellow flow and lyrics about his tough street life over scratchy and hissy beats from Doom, Dilla and DJ Premier – which were themselves based on ancient crate-dusty soul and jazz vinyl samples – Nehru is the anti-Earl Sweatshirt .
(17) Updated at 3.34pm BST 3.19pm BST 68th over: England 157-6 (Ali 51, Prior 8) Prasad returns, and engages Ali's bat more than Eranga, but he's right on top of things, playing the ball almost from in the crease; though this has been a slow innings, it's not been a scratchy one; he's played very few false shots.
(18) Milton's announcement about the consultation came towards the end of a scratchy debate in which Dorries said Cameron had initially encouraged her.
(19) I think we were just scratchy and hackles up and defensive.
(20) The child with no complaints other than discharge probably has a conjunctivitis, while the child with photophobia and a scratchy sensation should make one search for either a foreign body or a corneal problem.