(n.) Having inequalities, small ridges, or points, on the surface; not smooth or plain; as, a rough board; a rough stone; rough cloth.
(n.) Not level; having a broken surface; uneven; -- said of a piece of land, or of a road.
(n.) Not polished; uncut; -- said of a gem; as, a rough diamond.
(n.) Tossed in waves; boisterous; high; -- said of a sea or other piece of water.
(n.) Marked by coarseness; shaggy; ragged; disordered; -- said of dress, appearance, or the like; as, a rough coat.
(n.) Hence, figuratively, lacking refinement, gentleness, or polish.
(n.) Not courteous or kind; harsh; rude; uncivil; as, a rough temper.
(n.) Marked by severity or violence; harsh; hard; as, rough measures or actions.
(n.) Loud and hoarse; offensive to the ear; harsh; grating; -- said of sound, voice, and the like; as, a rough tone; rough numbers.
(n.) Austere; harsh to the taste; as, rough wine.
(n.) Tempestuous; boisterous; stormy; as, rough weather; a rough day.
(n.) Hastily or carelessly done; wanting finish; incomplete; as, a rough estimate; a rough draught.
(n.) Produced offhand.
(n.) Boisterous weather.
(n.) A rude fellow; a coarse bully; a rowdy.
(adv.) In a rough manner; rudely; roughly.
(v. t.) To render rough; to roughen.
(v. t.) To break in, as a horse, especially for military purposes.
(v. t.) To cut or make in a hasty, rough manner; -- with out; as, to rough out a carving, a sketch.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.
Scuffed
Definition:
(imp. & p. p.) of Scuff
Example Sentences:
(1) What a complete mess - a miscued shot, scuffed clearance, and uncontrolled toe-punt as he fell - but a decisive mess all the same."
(2) He is famously fastidious, too, once refusing to give a fellow player a lift after training in case he scuffed the leather seats of the new Becksmobile.
(3) The Arsenal forward attempted a Panenka, scuffed it badly, and scored anyway as the goalkeeper dived to his left.
(4) Moffat, who likes a pop from distance, winds up and drives a scuffed shot past the Colorado post.
(5) A case report is described of a patient who developed severe hypercalcemia during slow continuous arterio-venous ultrafiltration (SCUF).
(6) Danny Welbeck rolled the ball to Wayne Rooney who was in acres of space just 12 yards from the Bayern goal, but the Manchester United No10 scuffed a shot wide when he should have done much better.
(7) By analyzing the scuffed surfaces of the metatarsal bars, the physician can determine whether or not the bars are firm and thick enough and in the proper position to relieve and divert pressure from the metatarsal heads.
(8) 3.34pm BST 34 mins: Brilliant build up play by Suarez outside the box, as he drops a shoulder to create some space, then shimmies past one defender, but his left-footed shot is scuffed and straight to Krul for an easy save.
(9) The Celtic full-back Adam Matthews, allegedly a transfer target for Swansea City, reached the byline after a surging run down the right flank but he undermined his efforts with a scuffed cutback which the goalkeeper Dusan Kuciak comfortably gathered.
(10) At least it would have been forgivable had he managed to hit the target, instead of scuffing a tame effort the wrong side of Mignolet’s right-hand upright.
(11) Open Mon-Sat 10am-6pm, plus Sun noon-6pm in July and August The Oxford Bar Photograph: Alamy When the Inspector Rebus ITV series was relaunched in 2006, with Ken Stott stepping into the scuffed brogues of John Hannah, there was a feeling they had finally got the right man to play Ian Rankin's bruised copper.
(12) He was teed up by Gervinho, who had put the fear into Colombia with another dribble, but Kalou scuffed straight at Ospina from 18 yards.
(13) As it was, United were lucky Arnautovic, having scored a beauty, could not make it 3-0 after he ran clear on 36 minutes and a traumatic first half for Van Gaal was summed up by Daley Blind trying a cross from the left, scuffing it out of play and ending up on his backside.
(14) After a mild bout of playground scuffing, the ball's eventually hacked clear, Heskey playing a big part, Peter McGushin will be no doubt pleased to hear.
(15) Moyes was not the only person to put his hands to his head in disbelief when Osman, under no pressure, scuffed his shot wide.
(16) Iatrogenic damage to the temporomandibular joint included scuffing of the articular surfaces of the glenoid fossa and articular eminence (31.8%), scuffing of the condylar articular surface (9%), one disc perforation (4.5%) and one perforation of the medial capsule (4.5%).
(17) Khodorkovsky, wearing a scuffed black jacket, and Lebedev, in a white tracksuit top, whispered to each other inside the enclosed dock and ignored the judge as he said the court had established their guilt.
(18) In this way, Scarlett's death might serve a purpose, finally puncturing that quasi-colonial arrogance so endemic in a certain stratum of UK society - that our children can go off anywhere and somehow their Britishness, class and a scuffed copy of Lonely Planet will protect them, decades of increasingly cultured and sophisticated holidays having resulted in a generation of nomad-naifs who seem to think that the entire world is just one big, safe, fluffy Centre Parc, policed by the friendly ghost of Michael Palin.
(19) Then Sterling slipped Bony in and he scuffed a shot wide.
(20) True to character, they rallied with only a scuffed shot preventing Houghton from scoring and Germany’s Tabea Kemme surviving English claims that she should have conceded a handball penalty.