(n.) Having inequalities, small ridges, or points, on the surface; not smooth or plain; as, a rough board; a rough stone; rough cloth.
(n.) Not level; having a broken surface; uneven; -- said of a piece of land, or of a road.
(n.) Not polished; uncut; -- said of a gem; as, a rough diamond.
(n.) Tossed in waves; boisterous; high; -- said of a sea or other piece of water.
(n.) Marked by coarseness; shaggy; ragged; disordered; -- said of dress, appearance, or the like; as, a rough coat.
(n.) Hence, figuratively, lacking refinement, gentleness, or polish.
(n.) Not courteous or kind; harsh; rude; uncivil; as, a rough temper.
(n.) Marked by severity or violence; harsh; hard; as, rough measures or actions.
(n.) Loud and hoarse; offensive to the ear; harsh; grating; -- said of sound, voice, and the like; as, a rough tone; rough numbers.
(n.) Austere; harsh to the taste; as, rough wine.
(n.) Tempestuous; boisterous; stormy; as, rough weather; a rough day.
(n.) Hastily or carelessly done; wanting finish; incomplete; as, a rough estimate; a rough draught.
(n.) Produced offhand.
(n.) Boisterous weather.
(n.) A rude fellow; a coarse bully; a rowdy.
(adv.) In a rough manner; rudely; roughly.
(v. t.) To render rough; to roughen.
(v. t.) To break in, as a horse, especially for military purposes.
(v. t.) To cut or make in a hasty, rough manner; -- with out; as, to rough out a carving, a sketch.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.
Sleek
Definition:
(superl.) Having an even, smooth surface; smooth; hence, glossy; as, sleek hair.
(superl.) Not rough or harsh.
(adv.) With ease and dexterity.
(n.) That which makes smooth; varnish.
(v. t.) To make even and smooth; to render smooth, soft, and glossy; to smooth over.
Example Sentences:
(1) The gates may be open but the road to the church that calls itself a friendship and reconciliation centre is not paved with sleek cars or thronged with believers.
(2) And this as we learn that GCHQ, in all its technological majesty, can scoop up every last word that passes through those sleek cables beneath the Atlantic, everything we say and every last key that our fingers stroke.
(3) The unfairly maligned camel is a model of sleek, practical and elegant design compared with the clumsy creature the coalition has produced.
(4) Already known internationally for its food and its glittering annual film festival, the city will feature choral groups in the open air and an art project, Waves of Energy, bringing to life a surge of ideas suggested by the public, as well as performances and exhibitions inside sleek venues such as Basque music’s new home, Musikene, the San Telmo museum or the cube-shaped Kursaal on the edge of the sea.
(5) Scott delivered a film that glamorised the sleek contours of the military hardware and is powered by rapid-fire editing and a big-hair, big-shoulderpads pop soundtrack, making it one of the quintessential 80s films.
(6) Grilled meats ( txuleta means chop) are where he excels, but at the sleek interior bar you can also order flawlessly presented pintxos of seasonal produce.
(7) The issue with existing batteries is that they suck,” Elon Musk , chief executive of Tesla, said in May at the launch of the Powerwall , a sleek new battery.
(8) In a whir of lycra and straining calf muscles, the sleek, bent bodies flashed past, urged on by the crowds.
(9) These two saunas both boast the sleek, angular lines of Nordic architecture, and are built from ecologically friendly materials.
(10) After a false start in 2006 with a bill that was killed by parliament for being too weak, he launched a sleek new vehicle – “Turning the Corner” – in March 2007, with new emissions targets for each sector of the economy, crucially including oil and gas.
(11) Try, Robot: Darpa contest sends new humanoids into 'nuclear reactor' Read more On Saturday evening, with their sleek humanoid robot DRC-Hubo, a team of roboticists and engineers from the Korean Advanced Institute of Science and Technology in Daejeon, South Korea, won $2m from the R&D arm of the US defense department, Darpa, by outperforming 24 other robots in a simulated nuclear reactor.
(12) Photograph: Joha Gronvall In search of other public saunas in Helsinki I visited Kulttuurisauna , a sleek, modernist eco-sauna designed in 2013 by Tuomas Toivonen and Nene Tsuboi in the heart of the Merihaka district; and then to the other extreme, the tiny, self-service Sompasauna shacks on the banks of the Gulf Of Finland in the so-called Freezone of Sompasaari (a kind of Mad Max hinterland full of junk yards and disused buildings covered in graffiti).
(13) The Model 3 looks like a shorter version of the Model S, with a similar sleek profile, elongated hood and a panoramic glass roof.
(14) Just like iPhones and Kindles before it, the stylish and sleek iPad is becoming increasingly easy to spot in subway cars or on park benches across New York.
(15) Academics respond: Brexit would weaken UK university research and funding Read more “Certainly, few people here thought the outcome would have any major impact on their work,” said Vandevyver, a Belgian, sitting in a conference room on the school’s sleek, modernist campus on the city outskirts.
(16) The negative publicity - at odds with the company's sleek designs and 'Just Do It' slogan - has seen the sales of its trainers plummet.
(17) I’m staying at Hossan Lomakeskus , with accommodation in sleek wooden huts with floor-to-ceiling windows and uninterrupted views of Hossa lake.
(18) They chanted slogans and held up signs as a small, select group of people arrived in sleek sports cars and were ushered inside the relatively modest residence where the billionaire lives with his wife, Priscilla Chan.
(19) While most British Muslims can relate to having to buy a few essentials before Ramadan – dates, new hijabs, a sleek new abaya – for the vast majority of us, who are, to say the least, very unlikely to have a Harrods Rewards card, the idea of going on a vast Ramadan shopping spree is an alien concept.
(20) Take the sleek blue tram to rue Achard and, as you get off, you find yourself facing a squat terrace of abandoned houses.