(n.) Having inequalities, small ridges, or points, on the surface; not smooth or plain; as, a rough board; a rough stone; rough cloth.
(n.) Not level; having a broken surface; uneven; -- said of a piece of land, or of a road.
(n.) Not polished; uncut; -- said of a gem; as, a rough diamond.
(n.) Tossed in waves; boisterous; high; -- said of a sea or other piece of water.
(n.) Marked by coarseness; shaggy; ragged; disordered; -- said of dress, appearance, or the like; as, a rough coat.
(n.) Hence, figuratively, lacking refinement, gentleness, or polish.
(n.) Not courteous or kind; harsh; rude; uncivil; as, a rough temper.
(n.) Marked by severity or violence; harsh; hard; as, rough measures or actions.
(n.) Loud and hoarse; offensive to the ear; harsh; grating; -- said of sound, voice, and the like; as, a rough tone; rough numbers.
(n.) Austere; harsh to the taste; as, rough wine.
(n.) Tempestuous; boisterous; stormy; as, rough weather; a rough day.
(n.) Hastily or carelessly done; wanting finish; incomplete; as, a rough estimate; a rough draught.
(n.) Produced offhand.
(n.) Boisterous weather.
(n.) A rude fellow; a coarse bully; a rowdy.
(adv.) In a rough manner; rudely; roughly.
(v. t.) To render rough; to roughen.
(v. t.) To break in, as a horse, especially for military purposes.
(v. t.) To cut or make in a hasty, rough manner; -- with out; as, to rough out a carving, a sketch.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.
Thug
Definition:
(n.) One of an association of robbers and murderers in India who practiced murder by stealthy approaches, and from religious motives. They have been nearly exterminated by the British government.
Example Sentences:
(1) Thugs are distributing leaflets threatening to "wipe us out" and children in schools are being taught that the Rohingya are different.
(2) Mugabe and his Zanu-PF thugs, terrified of losing their empire, unleashed a carefully targeted anarchy at anyone who showed the slightest sign of dissent.
(3) "It took 21 days to get my hands on the brilliant Thug Life, whereas the book took me 77 days," he writes.
(4) But with a murderous thug ejected from power, who could object?
(5) Here's one entry: 1995: The government is full of jack-booted thugs in bucket helmets.
(6) In Ya’alon’s place is set to come a man routinely described as a thug, even if he did once serve as foreign minister.
(7) During the police repression of the Tunisian revolution, they were beaten by security thugs, and in rural areas around Kasserine some were raped by police after demonstrations.
(8) The commissioner of the Metropolitan police, Sir Paul Stephenson, said today that armed officers protecting Prince Charles and his wife Camilla as their car was attacked by student protesters showed "enormous restraint" and condemned the "thugs" who attacked the vehicle.
(9) After all, every veto holder had attacked another country in defiance of the charter, but no one had ever disputed the alleged Westphalian right of each anointed thug to mistreat his "own" people.
(10) "Free speech is a principle of our democracy, but the thugs that prompted violence ... represent in no way shape or form the Canadian way of life," Dimitri Soudas, the chief spokesman for the prime minister, Stephen Harper, said.
(11) "The media like to paint a picture of hooligans and thugs, mindless men on the rampage.
(12) She has no problem combining the roles of mother and hitperson: during one exchange of fire, she offs three thugs, then turns to her daughter and asks, "Honey, should we get a puppy?"
(13) Not surprisingly, the Thugs caught the imagination of the British at home (which is how the word "thug" entered the English language), and became a touchstone for colonial justifications for ruling India.
(14) Bikers for Trump: 'He'll get my vote because he's off his goddamn rocker' Read more Although Cleveland is the most fortified city in America at the moment, with thousands of police, FBI and secret service agents securing the Republican national convention, David – who won’t give me his last name but says he is from Minnesota – worries about “agitators” and “thugs” who make him feel unsafe.
(15) "If we are going to conduct a population-centric strategy in Afghanistan, and we are perceived as backing thugs, then we are just undermining ourselves," Major General Michael T Flynn, then the senior US military intelligence official in Afghanistan, was quoted as saying .
(16) Senator Lindsey Graham of South Carolina, a longstanding critic of Obama’s foreign policy credentials, urged the president to “do something” rather than deliver what he called empty threats to “thugs and dictators”.
(17) You used to be pretty certain, when a killing happened, that it was the work of the state, or thugs in the pay of the state.
(18) One of the emails mentioned Watson, who strongly denied any involvement, but the Sun branded him “a Brownite thug”.
(19) How embarrassing that some members of the government appear to have behaved in the manner of uncouth thugs – and towards someone representing the UN, which dared to question the bedroom tax.
(20) Hosni Mubarak launched his counter-revolution today, sending waves of armed thugs to do battle with pro-democracy demonstrators in Cairo and other cities.