(adv.) In a rough manner; unevenly; harshly; rudely; severely; austerely.
Example Sentences:
(1) By 24 hr, rough endoplasmic reticulum in thecal cells increased from 4.2 to 7% of cell volume, while the amount in granulosa cells increased from less than 3.5% to more than 10%; the quantity remained relatively constant in the theca but declined to prestimulation values in the granulosa layer.
(2) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(3) The cis isomer was retained longer in liver, particularly in mitochondria, but had low retention in that portion of the endoplasmic reticulum isolated as the rough membrane fraction.
(4) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(5) This heretogeneity occurred mainly as a progressive, decreasing gradient in the first half of this pathway, between the rough endoplasmic reticulum and the mi-cisternae of the Golgi apparatus.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Four fractions enriched, respectively, in plasma membrane (PM), smooth endoplasmic reticulum (SER), rough endoplasmic reticulum (RER), and mitochondria were isolated from estrogen-dominated rat myometrium.
(8) For trials in which the target was present in the array, RT functions were roughly symmetric, the shortest RTs being for extreme distractor ratios, and the longest RTs being for arrays in which there were an equal number of each distractor type.
(9) Classic technics of digital image analysis and new algorithms were used to improve the contrast on the full image or a portion of it, contrast a skin lesion with statistical information deduced from another lesion, evaluate the shape of the lesion, the roughness of the surface, and the transition region from the lesion to the normal skin, and analyze a lesion from the chromatic point of view.
(10) Electron microscopic evaluation of microsomal fractions showed elements of the plasma membrane, including cilia and microvilli, as well as rough and smooth endoplasmic reticulum.
(11) The local guide led us down a rough, uneven pathway, talking as he went.
(12) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(13) The interaction between PE and E-IgG involved the extension of micropseudopods toward adherent E-IgG, the formation of a linear uniform cap of roughly 200 A between opposing cell membranes, the ingestion of E-IgG by PE into a membrane-lined compartment, and the disintegration of the ingested ligand into membranous debris.
(14) Ultracentrifugally separated HDL2 and HDL3 roughly corresponded to HDL2e and HDL3e, respectively.
(15) The locations of these 15 insertion sites correlate well with the roughly estimated locations of five of the DNase I-hypersensitive subregions.
(16) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).
(17) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(18) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(19) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(20) That, roughly, was the theme of the Wednesday Play, Cathy Come Home, (BBC1) directed by Kenneth Loach, produced by Tony Garnett.
Rustic
Definition:
(a.) Of or pertaining to the country; rural; as, the rustic gods of antiquity.
(a.) Coarse; plain; simple; as, a rustic entertainment; rustic dress.
(a.) Simple; artless; unadorned; unaffected.
(n.) An inhabitant of the country, especially one who is rude, coarse, or dull; a clown.
(n.) A rural person having a natural simplicity of character or manners; an artless, unaffected person.
Example Sentences:
(1) Camp out, rustic-style, at the Observatorio Astronómico de la Tatacoa, 4km east of Villavieja.
(2) The rustic rooms have clay tiles and wooden furniture, and the walls are brightened up with local fabrics.
(3) Yet for all the colourful cushions, plants, rustic ivy-lined facade and local artworks, it’s the nouveau prices that most appeal.
(4) With the music, as in this summer’s Roman season: the composer Claire van Kampen , licensed by Globe boss Dominic Dromgoole, worked around the idea that the Romans imported their festive music, and its instruments, from North Africa, and got hold of Moroccan and rustic Spanish drums and buzz-booming shawms .
(5) and steaming up Norris's glasses with plans to turn the Rovers into a rustic-inspired gastropub with cross-generational plate-appeal ("Cumberland sausage is all the rage in Clitheroe …").
(6) There is a bucolic tendency running deep in the national character, expressing itself in a love of rustic poets and painters, and it is this part of us that has turned to fury at the coalition government and its prosaically named Draft National Planning Policy Framework.
(7) But when we get there the restaurant, with its rustic dacha -style Russian decor, leaves us both feeling slightly spooked.
(8) For something typical of the rustic northern countryside, try cabrito asado , a slow-roasted young goat cooked in a wood-burning oven.
(9) Maní is more rustic and informal than DOM – simple furniture, whitewashed walls and a ceiling of dried branches laid over rafters – but the food is no less adventurous.
(10) Anyone looking for simple, rustic, affordable experiences in priceless locations will find they’re in luck.
(11) Hidden gems and locals’ tips Mountain cabins In every highland region in Spain there will be a selection of rustic mountain cabins: refugios de montaña .
(12) This Anglo-Brazilian affair offers the best of both worlds: four rustic bungalows hidden away in rainforest, near a handful of easily accessed beaches.
(13) Cameron’s rustic ruin David Cameron has acquired a faux-rustic shepherd’s hut , in which he is hoping to write.
(14) Outside Kramatorsk's aerodrome, meanwhile, at the end of a rustic rutted alley lined with sycamores and apricots, protesters had set up a new camp.
(15) Inspired by the traditional architecture of Polish summer houses, or datchas , the owners have kitted out the apartments with real flair: rustic wooden furniture, sheepskin throws, woodburning stoves, luxury bedlinen and bathrooms.
(16) As well as rows of semi-automatic weapons of all colours and sizes there are tables with a range of handguns and accessories: Eagle grips in ultra pearl black and ivory polymer, Hornady bullets ("accurate, deadly, dependable") and general appeals to the rustic, manly and patriotic.
(17) The music marked the return of the accordion to French politics, not seen since the faux-rustic former president Valéry Giscard d'Estaing played it in the 1970s – an important message about Hollande's rural, Mr Normal image.
(18) Hernández re-creates not only their rustic speech, but also the natural prosody peculiar to the peasant.
(19) Winning tip: Casa Guedes, Porto Casa Guedes , in the old centre of Porto (130 Praças Poveiros) serves juicy slabs of roast pork in rustic brown rolls, stuck together with oozing sheep’s cheese.
(20) The fresh, contemporary decor – all cool whites and soft greys – makes a refreshing change from the heavy, rustic look typically found in French gîtes.