(superl.) Characterized by roughness; umpolished; raw; lacking delicacy or refinement; coarse.
(superl.) Unformed by taste or skill; not nicely finished; not smoothed or polished; -- said especially of material things; as, rude workmanship.
(superl.) Of untaught manners; unpolished; of low rank; uncivil; clownish; ignorant; raw; unskillful; -- said of persons, or of conduct, skill, and the like.
(superl.) Violent; tumultuous; boisterous; inclement; harsh; severe; -- said of the weather, of storms, and the like; as, the rude winter.
(superl.) Barbarous; fierce; bloody; impetuous; -- said of war, conflict, and the like; as, the rude shock of armies.
(superl.) Not finished or complete; inelegant; lacking chasteness or elegance; not in good taste; unsatisfactory in mode of treatment; -- said of literature, language, style, and the like.
Example Sentences:
(1) You need a little moleskine, to write rude ideas... Mel No, I’ve just started recycling them.
(2) I categorically never said that ‘Britain has so many paedophiles because it has so many Asian men’.” She added that it was “totally untrue” that she had threatened to “take this inquiry down with me”, and absolutely rejected being rude and abusive to junior staff.
(3) For a while yesterday, Hazel Blears's selfishly-timed resignation with her rude "rock the boat" brooch send shudders of revulsion through some in the party.
(4) Like low blood pressure after a heart attack, then, cheap oil should arguably be regarded not as a sign of rude health, but rather as a consequence of malaise.
(5) This country has had a free press for the last 300 years, that has been irreverent and rude as my website is and holding public officials to account.
(6) We had some memorable encounters and he was very rude to me.
(7) He privately told the privy counsellors' committee of inquiry set up to review the events leading up to the invasion: "If I may be very frank and rather rude, you had to keep the ball in the air with the Argentines.
(8) There will be dialogue and discussions about what works, rather than rude surprises that backfire.
(9) As Google states, it is definitely in the company’s best interest to get its first smartglass customers to behave, as “breaking the rules or being rude will not get businesses excited about Glass and will ruin it for other Explorers”.
(10) I think, in all honestly, if I could be Bradley Whitford I would be very, very happy.” He becomes almost drawlingly dreamy, rolling his “r”s as he leans against the warm oolite cliffs of this Jurassic Coast, until rudely interrupted by me, asking whether there’s talk of a Broadchurch 3 .
(11) If someone was rude to you, you were rude back to them.
(12) Brexiters face rude awakening on immigration, says ex-minister Read more The problem is, there is nothing on the horizon to suggest that achieving any significant reduction in immigration is achievable or even desirable.
(13) He repeatedly argued that his south London upbringing meant he was rude to people who were rude to him and said Jones needed to “get over it”, although he said that he was unaware of his colleague’s history of illness.
(14) When he sees what he's inherited, he may get a rude awakening.
(15) Having reassured ourselves that we’re justified in “holding them to account” and “having robust debates” and “speaking truth to power”, we’re now just flat-out rude to their faces?
(16) But the fact that there is a serious disagreement between Zimbabwe and the United Kingdom does not mean that you should then be discourteous or rude."
(17) I said to them afterwards: ‘If you’re not on it 100% in this league, you’ll get a rude awakening.’’” Albion must be sick of the sight of QPR and Charlie Austin in particular.
(18) I can think of hordes of politicians who look worse and "weirder", with wet little pouty-mouths, strange shiny skin, mad glaring eyes, deathly pale demeanour, blank gaze and an unhealthy quantity of fat (I can't name them, because it's rude to make personal remarks), and I don't hear anyone calling them "weird", or mocking their looks, except for the odd bold cartoonist, but when it comes to Miliband , it's be-as-rude-as-you-like time.
(19) She said something rude, and I picked up her arm and I bit it!
(20) So instead of asking for anything on her birthday, she gives her friends presents, and she regularly sticks bullies and rude policemen in trees.
Rued
Definition:
(imp. & p. p.) of Rue
Example Sentences:
(1) Moreover, the ribosylation inhibitors converted the glucocorticoid antagonist RU-486 into a potent agonist for cytolysis of L1210 cells.
(2) Decreased levels of receptors for estradiol-17beta, progesterone, and prolactin were found in the tumors remaining after ovariectomy while treatment with the dose (24 mug) of RU 16117, efficient to inhibit tumor growth, has a similar inhibitory effect on the levels of estradiol-17beta and prolactin receptors.
(3) Another two derivatives of RU 486, RU 42848 (didemethyl) and RU 42698 (propargyl), had lower RBA's than RU 486.
(4) Of these two pretreatment alternatives, RU 486 alone has the advantage of a shorter hospital stay.
(5) The in vitro susceptibility of Mycobacterium tuberculosis to a new macrolide antibiotic RU-28965, alone and in combination with rifampicin or isoniazid, was studied by the agar dilution method.
(6) Ru also increased to approximately double its control value.
(7) Raman intensities measured at 815 and 1100 cm-1 in spectra of poly (rI) and poly (rU)-poly (rA)-poly(rU) indicate that the correlation previously established for single- and double-stranded ribopolymer structures is valid also for these multi-stranded structures.
(8) Recent STM studies of calf thymus DNA and poly(rA).poly(rU) have shown that the helical pitch and periodic alternation of major and minor grooves can be visualized and reliably measured.
(9) Renal vascular resistance decreased during RU 486 administration in anesthetized (-25%) and unanesthetized (-19%) rats.
(10) Pretreatment of the lower airways with inhaled atropine did not affect the magnitude of the changes in Ru after inhalation of OA through the nose but significantly attenuated the response of the lower airways.
(11) The direct effect of RU 486 on LH secretion in the absence of exogenous progesterone was evaluated in cells cultured in the absence or presence of 10(-9) M estradiol and then treated for 4 to 24 h with increasing concentrations of RU 486 (10(-12) to 10(-5) M) and stimulated with GnRH (10(-9) M) during the last 3 h of incubation.
(12) Frances' highest administrative court ruled that the French government exceeded its authority in ordering the distribution of RU 497 (mifepristone), but ruled that French abortion law, allowing abortions in the 1st 10 weeks in "situations of distress," did not violate international treaties guaranteeing the "right to life."
(13) Interruption of early pregnancy is a major indication for RU-486.
(14) R units are either occupied (RO) or unoccupied (RU); C units are either active (CA) or inactive (CI).
(15) We report here on developmental changes in [3H]RU 28362 (glucocorticoid receptor) and [3H]aldosterone (mineralocorticoid receptor) binding capacity in soluble fractions prepared from hippocampal tissue.
(16) The antiglucocorticoid activity of the molecule can be demonstrated in humans by a rise in plasma cortisol, ACTH and LPH after RU 486 intake, and by blockade of some peripheral effects of cortisol.
(17) The antiprogesterone RU 486 was utilized to evaluate the possible role of progesterone in ovum maturation, ovulation, fertilization, and embryo cleavage.
(18) The selective D2 dopaminergic antagonists sulpiride (10(-5) M) totally abolished the effect of RU 24926 and partially abolished the effect of lisuride.
(19) The interaction of complexes Ru(bpy)n(TAP)3-n2+ (1a-1d for n = 0-3) with DNA has been investigated using photophysical methods (emission spectroscopy and laser flash photolysis), by studying the induction of single-strand breaks in plasmid DNA and the formation of adducts using 32P-labelled 27-mer oligonucleotides.
(20) Activation of C units persists as long as the "parent" R is occupied and is maintained for an additional short time interval (Tp) after RO reverts to RU, corresponding to hormone dissociation from receptor.