(1) Moreover, the ribosylation inhibitors converted the glucocorticoid antagonist RU-486 into a potent agonist for cytolysis of L1210 cells.
(2) Decreased levels of receptors for estradiol-17beta, progesterone, and prolactin were found in the tumors remaining after ovariectomy while treatment with the dose (24 mug) of RU 16117, efficient to inhibit tumor growth, has a similar inhibitory effect on the levels of estradiol-17beta and prolactin receptors.
(3) Another two derivatives of RU 486, RU 42848 (didemethyl) and RU 42698 (propargyl), had lower RBA's than RU 486.
(4) Of these two pretreatment alternatives, RU 486 alone has the advantage of a shorter hospital stay.
(5) The in vitro susceptibility of Mycobacterium tuberculosis to a new macrolide antibiotic RU-28965, alone and in combination with rifampicin or isoniazid, was studied by the agar dilution method.
(6) Ru also increased to approximately double its control value.
(7) Raman intensities measured at 815 and 1100 cm-1 in spectra of poly (rI) and poly (rU)-poly (rA)-poly(rU) indicate that the correlation previously established for single- and double-stranded ribopolymer structures is valid also for these multi-stranded structures.
(8) Recent STM studies of calf thymus DNA and poly(rA).poly(rU) have shown that the helical pitch and periodic alternation of major and minor grooves can be visualized and reliably measured.
(9) Renal vascular resistance decreased during RU 486 administration in anesthetized (-25%) and unanesthetized (-19%) rats.
(10) Pretreatment of the lower airways with inhaled atropine did not affect the magnitude of the changes in Ru after inhalation of OA through the nose but significantly attenuated the response of the lower airways.
(11) The direct effect of RU 486 on LH secretion in the absence of exogenous progesterone was evaluated in cells cultured in the absence or presence of 10(-9) M estradiol and then treated for 4 to 24 h with increasing concentrations of RU 486 (10(-12) to 10(-5) M) and stimulated with GnRH (10(-9) M) during the last 3 h of incubation.
(12) Frances' highest administrative court ruled that the French government exceeded its authority in ordering the distribution of RU 497 (mifepristone), but ruled that French abortion law, allowing abortions in the 1st 10 weeks in "situations of distress," did not violate international treaties guaranteeing the "right to life."
(13) Interruption of early pregnancy is a major indication for RU-486.
(14) R units are either occupied (RO) or unoccupied (RU); C units are either active (CA) or inactive (CI).
(15) We report here on developmental changes in [3H]RU 28362 (glucocorticoid receptor) and [3H]aldosterone (mineralocorticoid receptor) binding capacity in soluble fractions prepared from hippocampal tissue.
(16) The antiglucocorticoid activity of the molecule can be demonstrated in humans by a rise in plasma cortisol, ACTH and LPH after RU 486 intake, and by blockade of some peripheral effects of cortisol.
(17) The antiprogesterone RU 486 was utilized to evaluate the possible role of progesterone in ovum maturation, ovulation, fertilization, and embryo cleavage.
(18) The selective D2 dopaminergic antagonists sulpiride (10(-5) M) totally abolished the effect of RU 24926 and partially abolished the effect of lisuride.
(19) The interaction of complexes Ru(bpy)n(TAP)3-n2+ (1a-1d for n = 0-3) with DNA has been investigated using photophysical methods (emission spectroscopy and laser flash photolysis), by studying the induction of single-strand breaks in plasmid DNA and the formation of adducts using 32P-labelled 27-mer oligonucleotides.
(20) Activation of C units persists as long as the "parent" R is occupied and is maintained for an additional short time interval (Tp) after RO reverts to RU, corresponding to hormone dissociation from receptor.
Rung
Definition:
() of Ring
(p. p.) of Ring
() imp. & p. p. of Ring.
(n.) A floor timber in a ship.
(n.) One of the rounds of a ladder.
(n.) One of the stakes of a cart; a spar; a heavy staff.
(n.) One of the radial handles projecting from the rim of a steering wheel; also, one of the pins or trundles of a lantern wheel.
Example Sentences:
(1) Hancock is covering the same portfolios but has moved up a rung from his previous position as a parliamentary under secretary of state.
(2) In other cases local numbers were reported to state agencies but then not up the next rung, to the federal government.
(3) The National Association of Estate Agents said: "This announcement has added a new rung to the property ladder, one within reach of thousands of young families."
(4) They usually didn’t get him the best delivery times,” Runge said.
(5) In the first half of 2014, UK sales of vinyl are expected to be 1.2m, more than 50% up on the same period last year Hanging over everything Runge showed me was an awkward question.
(6) I've just rung my boss and my workplace is under water.
(7) But on the flip side you see a young boy and outstanding player in Amavi make the wrong decision at the wrong time to take someone on that late in the game, and unfortunately we came away with nothing.” Pardew had rung the changes at half-time as Palace struggled to find their rhythm and looked like a team with too many players in unfamiliar roles.
(8) "It's no good hoping people will climb the property ladder if the bottom rung is missing.
(9) are described: an analytical one, a Runge-Kutta simulation and an "asymptotic" method.
(10) The proposed law would only allow gay couples the right to adopt if they were married, not in a civil partnership – a distinction that has rung alarm bells among equality groups.
(11) The coupled equations for flow through collapsible tubes are solved using a Runge-Kutta finite difference scheme.
(12) For young people already struggling to reach the bottom rung of the housing ladder, it looks to be pulled up even further.
(13) And that was a good decision, I think.” Runge made regular trips to the plant at Orsman Road, N1, where he inspected what was on offer – not just presses, but an archive of the metallic master copies of stampers used to make thousands of different records, by artists including Simon & Garfunkel and the Manic Street Preachers, all of which could conceivably be put back into production.
(14) And helping borrowers move up the property chain can help free up homes lower down the chain for those borrowers looking to get on the first rung of the ladder."
(15) About 83.3 per cent were illiterate and belonged to the lowest rung of the socio economic scale.
(16) Edward M Kennedy, who died of brain cancer on Tuesday at the age of 77, was a man who made it his life's work to, as President Obama said in the funeral that took place in the church hours later, "give a voice to those who could not be heard", and to "add a rung to the ladder of opportunity".
(17) Study of cardiac arrhythmia may be pursued vertically, as up the rungs of a ladder, from symptom to ECG, to EPS, to local lesion, to intracellular metabolism and to alterations of the latter and their effects on charge-transfer by ions across the cell membrane.
(18) For Gabriela Salinas, commercial manager of a publishing company, the gender pay gap is particularly evident on the top rungs of the corporate world.
(19) Hoarding isn't the privilege of a few Saudi royals; it is a feature at almost every rung of the property ladder.
(20) Analysis by the Guardian of 50 of the UK's most valuable companies shows that women account for only 14% of staff serving on executive committees – the management level just one rung below the boardroom and which are viewed as the pipeline of talent to fill future board vacancies.