(n.) A bitter white crystalline substance obtained from the saccharinates and regarded as the lactone of saccharinic acid; -- so called because formerly supposed to be isomeric with cane sugar (saccharose).
Example Sentences:
(1) Since d-fenfluramine failed to alter saccharin preference, it is unlikely that the slowed eating rate induced by this compound indicates a reduction in food palatability.
(2) The onset of tolerance to morphine analgesia was studied in 34 female Wistar rats immediately after they drank a dextrose-saccharin cocktail or tap water for 6 or 24 hours.
(3) the colours: Allura red AC, erythrosine, canthaxanthin and the caramels; three anti-oxidants: BHA, BHT and the gallates; the sweeteners: polyols, aspartame, saccharin and cyclamates.
(4) The exposure of the mouse bladder to saccharin was very brief, because the time required for 50 percent of the compound to be eluted from the pellets was about 5.5 hours.
(5) The rats were then poisoned with lithium chloride after each of three sessions in an attempt to condition a taste aversion to the saccharin.
(6) The saccharin litters were mainly characterized by a slowering in the body growth evolution.
(7) 3-Amino[3-14C]benz[d]isothiazole-1, 1-dioxide was prepared from [3-14C]-saccharin.
(8) A shift of intake from 5% to 10% ethanol was also demonstrated with increasing time under shock, while saccharin and water intake decreased.
(9) A two-bottle choice test between the saccharin solution and water was given to all animals on the third and fourth days after the conditioning day.
(10) These results are consistent with reports which have found that rats selected for high or low alcohol intake have corresponding high and low intakes of saccharin.
(11) Other results revealed that ibotenic acid lesions of the insular cortex attenuated the reaction to the novel taste of saccharin in a familiar environment but failed to affect the ingestion of a novel food in a novel environment or passive avoidance learning.
(12) An illness-induced taste aversion was conditioned in rats by pairing saccharin with cyclophosphamide, an immunosuppressive agent.
(13) On each trial, access to saccharin at normal ambient temperature was followed by injection of drug or saline and placement for 6 hr into a temperature-controlled enclosure.
(14) However, saccharin does not trigger a fixed rate of lapping at any point in the sequence.
(15) Before and after treatment the following were recorded: subjective and objective nasal MCT time, using an original composition of vegetable charcoal powder and saccharin powder at 3%; nasal obstruction.
(16) They were trained to respond on a tongue-operated solenoid-driven drinking device that delivered 0.005 ml of a glucose and saccharin solution (G + S) per lick.
(17) Quantitation of o- and p-sulfamoylbenzoic acid residues in saccharin and its sodium salt is achieved by a method comprising methanolic extraction and high-performance ion exchange chromatography.
(18) Unlike typical carcinogens which interact with DNA, sodium saccharin is not genotoxic, but leads to an increase in cell proliferation of the urothelium, the only target tissue.
(19) The correlation between the FDD test, the Jones fluorescein test, and the saccharin taste test was low.
(20) Five-week-old F344 male rats were given sodium saccharin as 5% of the diet beginning either immediately (Group 1) or 2, 4, 6, or 18 weeks (Groups 2, 3, 4, or 5, respectively) after freezing of the bladder, and sacrificed 2 years after the start of the experiment.
Sugar
Definition:
(n.) A sweet white (or brownish yellow) crystalline substance, of a sandy or granular consistency, obtained by crystallizing the evaporated juice of certain plants, as the sugar cane, sorghum, beet root, sugar maple, etc. It is used for seasoning and preserving many kinds of food and drink. Ordinary sugar is essentially sucrose. See the Note below.
(n.) By extension, anything resembling sugar in taste or appearance; as, sugar of lead (lead acetate), a poisonous white crystalline substance having a sweet taste.
(n.) Compliment or flattery used to disguise or render acceptable something obnoxious; honeyed or soothing words.
(v. i.) In making maple sugar, to complete the process of boiling down the sirup till it is thick enough to crystallize; to approach or reach the state of granulation; -- with the preposition off.
(v. t.) To impregnate, season, cover, or sprinkle with sugar; to mix sugar with.
(v. t.) To cover with soft words; to disguise by flattery; to compliment; to sweeten; as, to sugar reproof.
Example Sentences:
(1) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(2) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(3) Their contour lengths varied from 0.28 to 51 micron, but unlike in the case of maize, a large difference was not observed in the distribution of molecular classes greater than 1.0 micron between N and S cytoplasms of sugar beet.
(4) As a group, the three mammalian proteins resemble bovine serum conglutinin and behave as lectins with rather broad sugar specificities directed at certain non-reducing terminal N-acetylglucosamine, mannose, glucose and fucose residues, but with subtle differences in fine specificities.
(5) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(6) 500-MHz H-NMR spectroscopy of the oligosaccharides derived from gamma-seminoprotein, a human seminal plasma glycoprotein, revealed considerable microheterogeneity both with respect to the degree of branching and with regard to the peripheral sugars.
(7) The percentage of energy from fat and added sugars and the amount of sodium and fibre in the diet tended to increase with energy intake.
(8) D-Mannitol has not so far been known as a major product of sugar metabolism by yeasts.
(9) The concentration dependences of response of frog tongue to D-fructose, D-glucose, and sucrose were almost the same, D-galactose, however, elicited a much larger response in comparison with the other sugars in the whole range of concentrations examined.
(10) A brevibacterium, strain TH-4, previously isolated by aerobic enrichment on the monocyclic monoterpenoid cis-terpin hydrate as a sole carbon and energy source, was found to grow on alpha-terpineol and on a number of common sugars and organic acids.
(11) These results provide no support for the claims that aprotinin prevents the activation of sugar transport in muscle by contractile activity or that bradykinin is the muscle activity hypoglycemia factor.
(12) Increased erythrocyte levels of the pyrimidine-sugar UDP-glucose were also found in patients with the highest orotidine levels.
(13) Each of the three A toxins consists of a single basic polypeptide chain of 93 to 99 residues, cross-linked by three or four disulfide bonds, lacking reducing sugar and cysteinyl residues.
(14) Well-refined x-ray structures of the liganded forms of the wild-type and a mutant protein isolated from a strain defective in chemotaxis but fully competent in transport have provided a molecular view of the sugar-binding site and of a site for interacting with the Trg transmembrane signal transducer.
(15) Two newly discovered enzymes have the capacity to metabolize these sugars but are not essential for their catabolism in wild-type cells.
(16) Often, flavorings such as chocolate and strawberry and sugars are added to low-fat and skim milk to make up for the loss of taste when the fat is removed.
(17) All components studied, namely amino-sugars, hexoses and neuraminic acid increased with age in men.
(18) The presence of serum in the phagocytosis assay did not affect either phagocytosis of Phz-treated RBCs or inhibition by sugars.
(19) In addition, 5-imino-derivatives of daunorubicin modified at sugar moiety were less effective in stimulating NADH oxidation and oxygen radical production than 5-iminodaunorubicin itself.
(20) Photobinding of 8-methoxypsoralen to 2'-deoxyadenosine also occurs, with covalent bond formation between carbon 3 or 4 of the pyrone ring and the sugar moiety of the nucleoside.