(n.) A bending or sinking between the ends of a thing, in consequence of its own, or an imposed, weight; an arching downward in the middle, as of a ship after straining. Cf. Hogging.
Example Sentences:
(1) When the posterior capsule was sectioned, no significant changes were noted in the severity of the sag or the rotation.
(2) Axonal regeneration with the ANG was equal to SAGs as measured by axonal diameters, physiological, and functional methods, although the SAG demonstrated statistically higher axonal counts.
(3) Yards away from a genuine station, he used a huge funnel to fill up a car sagging under the weight of its occupants and market produce.
(4) Guanacline, but not guanethidine or SAG, produced fluorescent lipopigment in all species examined.
(5) For cross-linked alpha alpha, however, the curve sags at temperatures somewhat below the region of principal cooperative loss of helix, the latter occurring at higher temperature but with the same steepness as in the non-cross-linked case.
(6) Myosin ATPase staining showed that about 80% of the LGM consists of type II A fibres, whilst the remainder are type II B. Physiological determination of the contractile properties of motor units indicated two classes of units: those that were relatively fatigue resistant and did not show a sag property (like fast-twitch, fatigue-resistant fibres or FR) and those that were relatively fatigable and did show a sag property (like fast-twitch, fatigable fibres or FF).
(7) The time-dependent sag elicited by hyperpolarization was reduced when Na+ or K+ was removed from the normal bath solution but was abolished with the removal of both Na+ and K+.
(8) In his bid to revitalise Spain's sagging monarchy, Felipe VI must be willing to show that he will handle things differently to his father, said Urreiztieta.
(9) By lacking possibilities of the comparison of equivalent (produced under the same preparation and storage conditions) concentrates of erythrocytes the higher transfusion efficiency of the SAG-S concentrates of erythrocytes to be expected could not be verified.
(10) This domed white building is now a magnet for national expectations, and many wonder whether it will sag under the weight of so much anticipation.
(11) Superantigens (SAg) interact with T lymphocytes bearing particular V beta sequences as part of their T cell receptor (TcR).
(12) Both produce substantial labeling of PC but [14C]SMG gives rise to the highest proportion of TG and the lowest of PA and PI, whereas [14C]SAG yields the opposite pattern.
(13) There is nowhere to go except further into an area of the city 750 metres wide by 500 metres deep that runs along the coast from the television station – with its pair of wrecked and punctured dishes – to the edge of District Two, overlooked by the pavilion and its sagging roof.
(14) As the temperature of the tarts increases a race will start between the sag of melting fat and the drying of the structure-forming gluten network.
(15) Several species were treated chronically with varying doses of guanethidine, guanacline or SAG; the superior cervical ganglia were examined light microscopically for neuronal destruction and for osmiophilic fluorescent lipopigment accumulation.
(16) An important exception concerned SE to which an equal antibody response is produced in high and low lines of sAg selection.
(17) Cheerful and eager to be helpful, he arrives to collect me the following morning, dressed in sagging brown corduroy jacket, faded blue T-shirt, blue silk cravat and socks beneath his Velcro-strapped sandals.
(18) A statistically significant improvement was observed, on the SAG score obtained during the follow-up, in patients (n = 16) who were not admitted to hospital in the 12 month period following discharge.
(19) Jannetta has summarized this concept as follows: "As we age, our arteries elongate and our brains 'sag'.
(20) The observation that ingrowth of SAG neurites to presumptive sensory areas of the inner ear preceded cytodifferentiation of those receptor cells suggested a causal relationship.
Tight
Definition:
() of Tie
() p. p. of Tie.
(superl.) Firmly held together; compact; not loose or open; as, tight cloth; a tight knot.
(superl.) Close, so as not to admit the passage of a liquid or other fluid; not leaky; as, a tight ship; a tight cask; a tight room; -- often used in this sense as the second member of a compound; as, water-tight; air-tight.
(superl.) Fitting close, or too close, to the body; as, a tight coat or other garment.
(superl.) Not ragged; whole; neat; tidy.
(superl.) Close; parsimonious; saving; as, a man tight in his dealings.
(superl.) Not slack or loose; firmly stretched; taut; -- applied to a rope, chain, or the like, extended or stretched out.
(superl.) Handy; adroit; brisk.
(superl.) Somewhat intoxicated; tipsy.
(superl.) Pressing; stringent; not easy; firmly held; dear; -- said of money or the money market. Cf. Easy, 7.
(v. t.) To tighten.
Example Sentences:
(1) Freshly isolated sarcoplasmic reticulum vesicles contain 0.05 mol of tightly bound ADP and 0.03 mol of tightly bound ATP per mol of Ca2+, Mg2+-ATPase (ATP phosphohydrolase, EC 3.6.1.3).
(2) The expression of the Pgp isoforms appears to be tightly regulated and, at least in some cells, under complex hormonal control.
(3) Whereas the tight junctions of endoneurial capillaries are known to prevent certain blood-borne substances from entering the endoneurium, it was not clear whether the permeability of the pulpal capillaries, which are distant from the nerve fibres, could affect the nerve fibre environment.
(4) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(5) These data indicate that topoisomerase I and RNA polymerase I are tightly complexed both in vivo and in vitro, and suggest a role for DNA topoisomerase I in the transcription of ribosomal genes.
(6) Immunofluorescence and immunoelectronmicroscopy experiments demonstrated that while tight junctions demarcate PAS-O distribution in confluent cultures, apical polarity could be established at low culture densities when cells could not form tight junctions with neighboring cells.
(7) Investigations have been made to determine the identity and binding characteristics of the pterins that are bound tightly to dihydrofolate reductases which are isolated from vertebrate sources by a well established procedure.
(8) At all times, a tight inverse correlation exists between ATP and IMP concentrations.
(9) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).
(10) This study investigates the use of the incentive inspirometer to observe the effects of tight versus loose clothing on inhalation volume with 17 volunteer subjects.
(11) In contrast, interchange of the histones and tightly bound non-histone protein DNA complexes from hormone-withdrawn and estrogen-stimulated chromatins during reconstitution did not affect the level of mRNAOV sequences produced.
(12) Using microelectrodes and various microscopic techniques active Na+ absorption as well as K+ secretion has been localized to the principal cells, while Cl- absorption was found to proceed largely, though not exclusively, through the tight junctions between cells.
(13) The successful establishment of a postcrisis SV-40 T antigen transformed epithelial cell line, 1HAEo-, which retains tight junctions and vectorial ion transport, is described.
(14) The present investigation shows that the intramembranous proteins of tight and gap junctions are mobile structures within the fluid membrane.
(15) In contrast, after incubation with 0.5% DOC, the core microfilaments are no longer tightly bundled yet the lateral arms remain attached with a distinct 33-nm periodicity.
(16) The data collected by several approaches reveal that assembly and maturation of vaccinia involves a tightly coupled sequence of interrelated events including the assembly of the envelope, post-translational cleavage of several virion polypeptides, and induction of the core enzymes.
(17) The tight coupling between neuronal activity and oxidative energy metabolism forms the basis for the use of cytochrome oxidase as an endogenous metabolic marker for neurons.
(18) When using a nylon thread for the attachment of a pseudophakos to the iris, it may happen that the suture is slung tightly around the implant-lens.
(19) Some antibodies and other proteins bind tightly to nitrocellulose and dissociation of these proteins by Tween 20 is barely detectable.
(20) Independent experts warn that rumours and deliberate misinformation about the regime are rife, partly because it is impossible to verify or disprove most stories about the tightly controlled country's elite.