(n.) The state of being satiated or glutted; fullness of gratification, either of the appetite or of any sensual desire; fullness beyond desire; an excess of gratification which excites wearisomeness or loathing; repletion; satiation.
Example Sentences:
(1) Duodenal infusions of glucose inhibited FI calorically, and generally inhibited GE calorically; but gastric volume at satiety was always equal to control volume.
(2) We considered that if CCK-induced reductions in food intake occur through the mechanism of normal satiety, CCK-induced satiety and normal satiety should respond in the same way to a pharmacological challenge.
(3) The results are consistent with the view that satietin acts by activating a satiety mechanism.
(4) This suggests that brain 5-HT may influence primarily the induction of satiety rather than the suppression of hunger.
(5) It is concluded that at the first central synapse of the taste system of the primate, neural responsiveness is not influenced by the normal transition from hunger to satiety.
(6) The results of these studies, considered as a whole, support the view that McCleary's osmotic postingestional satiety signal acts as an intestinal distention signal rather than by inducing thirst.
(7) Acarbose significantly reduced the satiety effect of corn starch in lean rats (p less than 0.001), and further attenuated satiety in obese rats (p less than 0.02).
(8) Attention to focal stimulation did not mediate differences in sensitivity to satiety cues within the C group.
(9) Eating, in turn, activates inhibitory signals to produce satiety.
(10) Intracarotid administration of isotonic glucose (0.5 ml of 5.4%) in the starving albino rats produced an increase in the multiunit activity (MUA) of ventromedial hypothalamus (satiety centre) and a decrease in the MUA of the lateral hypothalamic area (feeding centre).
(11) Under the conditions of this study, energy density of foods seemed to play a significant role on the occurrence of satiety.
(12) The satiety-inducing effects of centrally and peripherally administered cholecystokinin (CCK) in experimental animals have been well documented.
(13) It is suggested that the ventromedial and lateral hypothalamus are connected by reciprocal circuits, so that activation of the ventromedial center results in stimulation of the lateral beta receptors which inhibit the lateral "feeding" cells, and activation of the lateral center results in stimulation of the ventromedial alpha receptors which inhibit the ventromedial "satiety" cells.
(14) These results suggest that endogenous CCK causes satiety by an agonist action on CCK-B receptors in the brain.
(15) In sensory-specific satiety, the pleasantness of the sight or taste of a food becomes less after it is eaten to satiety, whereas the pleasantness of the sight or taste of other foods which have not been eaten is much less changed; correspondingly, food intake is greater if foods which have not already been eaten to satiety are offered.
(16) These tablets undergo expansion in the stomach and are expected to cause early satiety.
(17) These results indicate that 5-HT exerts its anorectic effect only after some food has been ingested, and support the hypothesis that 5-HT accelerates the development of satiation and satiety.
(18) Thus, CCK concentrations in specific areas of the hypothalamus increased with feeding, supporting the potential role of CCK in the central nervous system as a satiety peptide.
(19) Closing the gastric cannula increased the potency with which ip glucose inhibited eating, suggesting synergy of postabsorptive glucose with other postgastric satiety signals.
(20) The results are discussed in terms of a possible role for peripheral 5-HT in the control of satiety, and implications for the mode of action of serotonergic anorectic agents such as fenfluramine.
Surfeit
Definition:
(n.) Excess in eating and drinking.
(n.) Fullness and oppression of the system, occasioned often by excessive eating and drinking.
(n.) Disgust caused by excess; satiety.
(v. i.) To load the stomach with food, so that sickness or uneasiness ensues; to eat to excess.
(v. i.) To indulge to satiety in any gratification.
(v. t.) To feed so as to oppress the stomach and derange the function of the system; to overfeed, and produce satiety, sickness, or uneasiness; -- often reflexive; as, to surfeit one's self with sweets.
(v. t.) To fill to satiety and disgust; to cloy; as, he surfeits us with compliments.
Example Sentences:
(1) I'm reminded of something Cooper said earlier, when talking about the pressures of this time of year for working parents, with its surfeit of plays and, "Oh God, not another school fair".
(2) This very tight clustering suggests a cis interaction between adjacent Surfeit genes.
(3) The clustered arrangement (no two adjacent genes are separated by more than 73 base pairs [bp] and two genes overlap by 133 bp at their 3' ends) of the four genes (Surf-1 to -4) identified so far in the mouse surfeit locus (T. Williams, J. Yon, C. Huxley, and M. Fried, Proc.
(4) The organization of the mouse surfeit locus is unusual in that it contains six housekeeping genes (Surf-1-Surf-6), which are unrelated by sequence homology, in the tightest mammalian gene cluster thus far described.
(5) When the faculty status of women and men academic anesthesiologists was examined a significant difference was found in rank distribution in age groups 40 to 44 (P less than 0.005) and 45 to 49 (P less than 0.001), where there was a deficit of professors and a surfeit of instructors among women.
(6) Here's Niall Mullen: "As a Liverpool fan who can barely buy his own groceries I am going to be outraged, outraged I tell you, if we fail to procure a player I've never heard of, who plays in a position in which we have a surfeit of players, for a club I've never seen play."
(7) We found no evidence of an initial surfeit of processing units, dendritic branches, or synapses.
(8) In this endocrine control, the renin axis provides the primary defence against sodium volume depletion and hypotension while atrial hormone plays an increasingly active counter-role for coping with situations that involve a sodium-volume surfeit or rising blood volume or blood pressure levels.
(9) Profound changes are occurring in the health care system, including a surfeit of physicians, cost containment, and competition.
(10) Using an interspecies backcross, we have mapped the HOX-5 and surfeit (surf) gene clusters within the proximal portion of mouse chromosome 2.
(11) In the adult, sodium surfeit is associated with an increase in urinary dopamine; the opposite occurs in the young.
(12) But we've had a surfeit of "behind the scenes" pictures of both coalition leaders; too many pictures of Cameron gurning at his new baby have led to this sort of material becoming a devalued currency.
(13) Responses to the energy surfeit led to intakes 104% and 116% of baseline, respectively.
(14) Since a repository would be expected to accumulate surplus material, one would predict that phosphorylase, which contains stoichio-metric amounts or pyridoxal phosphate, would increase in muscle of animals surfeited with the vitamin.
(15) What is called progress seems often to bring a surfeit of new experiences, facts, machines, noises, producing a feeling of helplessness, almost of despair.
(16) These data support the hypothesis that a surfeit of opioidergic ligand may potentiate drinking of alcoholic beverages.
(17) The concept of a basal level of body sodium (Strauss' state 'between surfeit and deficit') was studied by means of body sodium measurements in rats on different sodium intakes, in some cases after diuretic pretreatment.
(18) The invading fibers appear to encounter resistance at the basal lamina, but, once within the epithelium, at embryonic days 8-9, they form a surfeit of branches in columnar zones oriented radially toward the surface.
(19) Relative to their energy consumption on the medium-fat diet, the subjects spontaneously consumed an 11.3% deficit on the low-fat diet and a 15.4% surfeit on the high-fat diet (p less than 0.0001), resulting in significant changes in body weight (p less than 0.001).
(20) The mouse surfeit locus is unusual in that it contains a number of closely clustered genes (Surf-1, -2, and -4) that alternate in their direction of transcription (T. Williams, J. Yon, C. Huxley, and M. Fried, Proc.