(a.) Undisturbed by passion or caprice; calm; tranquil; serene; not passionate or giddy; composed; staid; as, a sedate soul, mind, or temper.
Example Sentences:
(1) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(2) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(3) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).
(4) Although lorazepam and haloperidol produced an equivalent mean decrease in aggression, significantly more subjects who received lorazepam had a greater decrease in aggression ratings than haloperidol recipients; this effect was independent of sedation.
(5) Adverse outcomes were reported more frequently by consultant physicians, by those who 'titrated' the intravenous sedative, and by those who used an additional intravenous agent, but were reported equally frequently by endoscopists using midazolam and endoscopists using diazepam.
(6) Alterations in mean systolic blood pressure appeared to be modest, consisting of a 10 percent decrease from the control level, related to sedation, and a 10 percent rise from baseline during the procedure, associated with a concomitant mild tachycardia.
(7) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(8) A survey into the current usage of tracheal tubes and associated procedures, such as various sedation regimes and antacid therapy, in intensive care units was carried out in Sweden by sending a questionnaire to physicians in charge of intensive care units in 70 acute hospitals which included seven main teaching hospitals.
(9) The results show that both drugs possess sedative, antispasmodic, antipyretic, antiinflammatory, cardiotonic and hypotensive effects, the strength of effect and toxicity being similar.
(10) This suggests that the fluphenazine-induced sedation is not mediated via its effect on brain NA content, but is possibly due to the effect of the drug on NA turnover rates in the brain.
(11) The introduction of non-sedating H1-selective antihistamine drugs and local corticosteroids has been an important therapeutic advance.
(12) Neither a sedative nor other side effects could be seen.
(13) Sedation was measured by asking the subjects to complete visual analog scales.
(14) Smoking behaviour, self-reported mood and cardiac activity were examined in 12 "sedative" and 12 "stimulant" smokers, defined using Mangan and Golding's questionnaire.
(15) Patients in the reference group used more sedatives and long-acting nitroglycerine and had a lower return-to-work rate during the study period.
(16) A prospective study of the necessity of sedation, or analgesia, or both in total colonoscopy was performed.
(17) Fifteen consecutive patients on peritoneal dialysis who complained of chronic sleep disturbance and requested sedative were selected.
(18) Sedative interaction between midazolam and morphine was found to have a tendency for synergism (interaction coefficient of 1.56, P greater than 0.05) with decreased individual variability in the sedative response to the combination.
(19) Both drugs were relatively well tolerated, but trimipramine had a sedative effect which proved troublesome in some patients.
(20) None of the patients required anaesthesia, analgesics or sedatives.
Somnolence
Definition:
(n.) Alt. of Somnolency
Example Sentences:
(1) Lethargy and somnolence were reported on both capsule and tablet by several subjects at a time which corresponded with the maximum concentration of drug in plasma.
(2) On admission, the patient's state of consciousness deteriorated from somnolence to coma.
(3) This was generally mild and always fully reversible and consisted mainly of forgetfulness, occasionally hallucinations, nightmares and somnolence.
(4) A 63-year-old man was admitted to our hospital with tremor and somnolence, followed soon by coma.
(5) Diminished salivary flow was significantly greater with amitriptyline, as were complaints of dry mouth, somnolence, dizziness, and headache.
(6) Somnolence, hypotonia, weight gain, excitation, and insomnia were the most common problems at the beginning of the study and were usually transient.
(7) A 60-year-old woman who for many years had been taking salicylate-containing tablets for headaches, was admitted to hospital, in a somnolent state, because of increasing weakness, tiredness, memory and speech disorders, and tinnitus.
(8) The central anticholinergic syndrome (CAS) includes central signs (somnolence, confusion, amnesia, agitation, hallucinations, dysarthria, ataxia, delirium, stupor, coma) and peripheral signs (dry mouth, dry skin, tachycardia, visual disturbances and difficulty in micturition).
(9) During three month periods, the patient progressively became somnolent, speechless and immobile.
(10) Our data demonstrate that patients with diagnosable disorders of excessive somnolence may be discordant on the two tests (eg, having low sleep latency on MSLT but high sleep latency on MWT).
(11) Tolerance was good with the rare problem of somnolence.
(12) Neurological examination on admission revealed somnolence and right-hemiparesis.
(13) The clinical features include overwhelming episodes of sleep, excessive daytime somnolence, hypnagogic hallucinations, disturbed nocturnal sleep; manifestations of dissociated REM sleep inhibitory process, cataplexy and sleep paralysis; and a special polygraphic pattern: the sleep onset REM episode.
(14) Symptoms of excessive daytime somnolence range from mild to severe.
(15) Subjects with a history of post-irradiation somnolence syndrome were significantly older at diagnosis than nonsomnolent subjects.
(16) In some cases there was a marked additional fall of arterial pressure in the orthostatic position, a sensation of dryness in the mouth, weakness and mild somnolence.
(17) The results indicate that inattention and somnolence negatively influence memory performance and should be taken into account when evaluating the Amytal memory test results.
(18) Clinical symptoms include excessive daytime somnolence, overwhelming daytime sleep episodes, attacks of cataplexy, hypnagogic hallucinations, sleep paralysis and disturbed nocturnal sleep; sleep onset REM episodes are the main polygraphic feature.
(19) Patients with the hypersomnia-sleep apnea syndrome should be provided with a tracheal opening during sleep when severe daytime somnolence, cardiac arrhythmias, and hypertension are present.
(20) The decreased somnolence and increased libido and potency which accompanied therapy with levodopa suggest damage to dopaminergic and noradrenergic pathways.