(1) The results support the speculation that the product of SELD is a phosphoselenoate with the phosphate moiety derived phosphoselenoate from the gamma-phosphate group of ATP.
(2) The biological activities of the wild type and mutant proteins were studied using E. coli MB08 (selD-) transformed with plasmids containing the selD genes.
(3) Purified SELD protein is a monomer of 37 kDa in its native state and catalyses a selenium-dependent ATP-cleavage reaction delivering AMP and releasing the beta-phosphate as orthophosphate.
(4) Moreover, synthesis of enzymically active protein in a transformed E. coli selD mutant strain indicated that there is a nonspecific mechanism of selenocysteine incorporation.
(5) Transformation of the mutant Salmonella strain with a plasmid bearing the E. coli selD gene restored formate dehydrogenase activity, 75Se incorporation into formate dehydrogenase seleno-polypeptides and [75Se]seleno-tRNA synthesis.
(6) Mutation of a single gene, referred to as selA1 in Salmonella typhimurium and as selD in Escherichia coli, results in the inability of these organisms to insert selenium specifically into the selenopolypeptides of formate dehydrogenase and into the 2-selenouridine residues of tRNAs.
(7) The formation of selenocysteine depended on the presence of functional products of the selA and selD genes but not of the selB gene.
(8) 4) SELD however, was accompanied by the longer duration of surgery with more blood loss and by higher incidence of complications, than conventional R2, R3 dissection.
(9) This fact seems to warrant SELD for advanced gastric cancer.
(10) Complementation of the mutation in S. typhimurium with the selD gene from E. coli indicates functional identity of the selA1 and selD genes.
(11) For male Ss, verbal reinforcement increased self-disclosure relative to the interviewer seld-disclosure condition.
(12) In the absence of the complementary enzyme(s), the SELD protein catalyzes the synthesis of a labile selenium donor compound from selenide and ATP.
(13) The longer initiated just upstream of the orf183 gene, whereas the 5' end of the other mapped in a 116-bp nontranslated region between orf183 and selD.
(14) Four genes have been identified so far: selA and selB (at the fdhA locus), selC (previously fdhC), and selD (previously fdhB).
(15) It was precluded that any putative covalent or non-covalent ligand of SELD not removed during purification participated in the reaction.
(16) However, supplementation of the deficient enzyme preparation with the purified selD gene product (SELD protein) restored synthesis of seleno-tRNAs.
(17) Transformation with an additional plasmid carrying an E. coli formate dehydrogenase selenopolypeptide-lacZ gene fusion showed that the selD gene allowed readthrough of the UGA codon and synthesis of beta-galactosidase in the Salmonella mutant.
(18) The selD gene from Escherichia coli, whose product is involved in selenium metabolism, has been cloned and sequenced.
(19) Gene disruption experiments demonstrated that the SelD protein is required both for the incorporation of selenium into the modified nucleoside 5-methylaminomethyl-2-selenouridine of tRNA and for the biosynthesis of selenocysteine from an L-serine residue esterbonded to tRNA(Ser)(UCA).
(20) One hundred and sixty three cases of gastric cancer, treated with SELD is reviewed.
Self
Definition:
(a.) Same; particular; very; identical.
(n.) The individual as the object of his own reflective consciousness; the man viewed by his own cognition as the subject of all his mental phenomena, the agent in his own activities, the subject of his own feelings, and the possessor of capacities and character; a person as a distinct individual; a being regarded as having personality.
(n.) Hence, personal interest, or love of private interest; selfishness; as, self is his whole aim.
(n.) Personification; embodiment.
Example Sentences:
(1) Questionnaires were used and the respondent self-designation method measured leadership.
(2) Participants (n=165) entering a week-long outpatient education program completed a protocol measuring self-care patterns, glycosylated hemoglobin levels, and emotional well-being.
(3) Results show diet, self-control and parts of insulin-therapy to be problematic treatment components.
(4) The authors empirically studied the self-medication hypothesis of drug abuse by examining drug effects and motivation for drug use in 494 hospitalized drug abusers.
(5) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(6) When compared with self-reported exposures, the sensitivity of both job-exposure matrices was low (on average, below 0.51), while the specificity was generally high (on average, above 0.90).
(7) The voters don’t do gratitude, self-pitying politicians are wont to moan.
(8) Electron self-exchange has been measured by an NMR technique for horse-heart myoglobin.
(9) In self-opinions on own appearance the children mentioned teeth as a feature which they would like to change as first.
(10) It is proposed that microoscillations of the eye increase the threshold for detection of retinal target displacements, leading to less efficient lateral sway stabilization than expected, and that the threshold for detection of self motion in the A-P direction is lower than the threshold for object motion detection used in the calculations, leading to more efficient stabilization of A-P sway.
(11) If black people could only sort out these self-inflicted problems themselves, everything would be OK. After all, doesn't every business say it welcomes job applicants from all backgrounds?
(12) Subjects who reported incidents of childhood sexual exploitation had lower levels of self-esteem and higher levels of depression than the comparison group.
(13) Right hemisphere inactivation caused a decrease in the frequency of lateral hypothalamus self-stimulation, whereas with left hemisphere inactivation it increased, which testifies to right hemisphere dominance in self-stimulation reaction.
(14) Poly (8NH2G) does not interact with poly(C) in neutral solution because of the high stability of the hemiprotonated G-G self-structure.
(15) In invasive epidermoid carcinoma, the accuracy with the self-collected specimens approached the physician-scraped specimens.
(16) US presidential election 2016: the state of the Republican race as the year begins Read more So far, the former secretary of state seems to be recovering well from self-inflicted wounds that dogged the start of her second, and most concerted, attempt for the White House.
(17) A study was conducted to determine the usefulness of self-screening of blood pressure in families as part of a school health care programme, and to study the relationship between BP and sodium excretion in school children.
(18) However, self-efficacy (defined as confidence in being able to resist the urge to drink heavily) assessed at intake of treatment, was strongly associated with the level of consumption on drinking occasions at follow-up.
(19) Jeremy Corbyn could learn a lot from Ken Livingstone | Hugh Muir Read more High-minded commentators will say that self-respect – as well as Burke’s dictum that MPs are more than delegates – should be enough to make members under pressure assert their independence.
(20) In a family with hereditary elliptocytosis and an abnormality in spectrin self-association, the membranes had decreased deformability and stability.