(1) The results support the speculation that the product of SELD is a phosphoselenoate with the phosphate moiety derived phosphoselenoate from the gamma-phosphate group of ATP.
(2) The biological activities of the wild type and mutant proteins were studied using E. coli MB08 (selD-) transformed with plasmids containing the selD genes.
(3) Purified SELD protein is a monomer of 37 kDa in its native state and catalyses a selenium-dependent ATP-cleavage reaction delivering AMP and releasing the beta-phosphate as orthophosphate.
(4) Moreover, synthesis of enzymically active protein in a transformed E. coli selD mutant strain indicated that there is a nonspecific mechanism of selenocysteine incorporation.
(5) Transformation of the mutant Salmonella strain with a plasmid bearing the E. coli selD gene restored formate dehydrogenase activity, 75Se incorporation into formate dehydrogenase seleno-polypeptides and [75Se]seleno-tRNA synthesis.
(6) Mutation of a single gene, referred to as selA1 in Salmonella typhimurium and as selD in Escherichia coli, results in the inability of these organisms to insert selenium specifically into the selenopolypeptides of formate dehydrogenase and into the 2-selenouridine residues of tRNAs.
(7) The formation of selenocysteine depended on the presence of functional products of the selA and selD genes but not of the selB gene.
(8) 4) SELD however, was accompanied by the longer duration of surgery with more blood loss and by higher incidence of complications, than conventional R2, R3 dissection.
(9) This fact seems to warrant SELD for advanced gastric cancer.
(10) Complementation of the mutation in S. typhimurium with the selD gene from E. coli indicates functional identity of the selA1 and selD genes.
(11) For male Ss, verbal reinforcement increased self-disclosure relative to the interviewer seld-disclosure condition.
(12) In the absence of the complementary enzyme(s), the SELD protein catalyzes the synthesis of a labile selenium donor compound from selenide and ATP.
(13) The longer initiated just upstream of the orf183 gene, whereas the 5' end of the other mapped in a 116-bp nontranslated region between orf183 and selD.
(14) Four genes have been identified so far: selA and selB (at the fdhA locus), selC (previously fdhC), and selD (previously fdhB).
(15) It was precluded that any putative covalent or non-covalent ligand of SELD not removed during purification participated in the reaction.
(16) However, supplementation of the deficient enzyme preparation with the purified selD gene product (SELD protein) restored synthesis of seleno-tRNAs.
(17) Transformation with an additional plasmid carrying an E. coli formate dehydrogenase selenopolypeptide-lacZ gene fusion showed that the selD gene allowed readthrough of the UGA codon and synthesis of beta-galactosidase in the Salmonella mutant.
(18) The selD gene from Escherichia coli, whose product is involved in selenium metabolism, has been cloned and sequenced.
(19) Gene disruption experiments demonstrated that the SelD protein is required both for the incorporation of selenium into the modified nucleoside 5-methylaminomethyl-2-selenouridine of tRNA and for the biosynthesis of selenocysteine from an L-serine residue esterbonded to tRNA(Ser)(UCA).
(20) One hundred and sixty three cases of gastric cancer, treated with SELD is reviewed.
Weld
Definition:
(v. t.) To wield.
(n.) An herb (Reseda luteola) related to mignonette, growing in Europe, and to some extent in America; dyer's broom; dyer's rocket; dyer's weed; wild woad. It is used by dyers to give a yellow color.
(n.) Coloring matter or dye extracted from this plant.
(v. t.) To press or beat into intimate and permanent union, as two pieces of iron when heated almost to fusion.
(v. t.) Fig.: To unite closely or intimately.
(n.) The state of being welded; the joint made by welding.
Example Sentences:
(1) Tests were undertaken to study resistance to tears in laser welded dental metal alloys.
(2) The possibility of contaminating the breathing air zone with hazardous substances in manual and semi-automated welding increases with the intensity of their formation in the arc zone.
(3) Laser repair has not been widely accepted both because the effect of laser irradiation on intact nerves is not well documented, and the anastomotic strength of the weld has been inferior to suture repair.
(4) The highest combined exposure (10-fold allowable value) was that of welders of steel coated with the zinc layer, using the metal active gas welding.
(5) The concentrations of 17 trace elements (e.g., copper, cobalt, iron, manganese, chromium, silicon and magnesium) were determined in whole blood samples of 81 persons working with different welding methods on stainless steel or aluminium and 68 nonwelders.
(6) These figures represent a participation rate of 37.1% in welders and 36.7% in non-welding subjects.
(7) Weak welds occurred with no thermal damage obtained at lower irradiances: stronger welds with thermal damage confined to the weld site occurred at higher irradiances.
(8) The results support the hypothesis that mild steel welding and to a lesser extent stainless steel welding with tungsten inert gas is associated with reduced semen quality at exposure in the range of the Danish process specific threshold limit values of welding.
(9) Low-level exposure to hexavalent chromium associated with TIG stainless steel and mild steel welding do not appear to be a major hazard for human spermatogenesis.
(10) Whereas the patterns of lung cancer mortality in these results suggest that the risk of lung cancer is higher for stainless steel than mild steel welders the different level of risk for these two categories of welding exposure cannot be quantified with precision.
(11) The occurrence of reduced birthweight, preterm delivery, infant mortality, and congenital malformation was not increased among children at risk from paternal welding exposure in comparison with children not at risk.
(12) The goal of future research should be to make the procedure less operator-dependent (dye enhanced or automated welding).
(13) When nacreous shell produced by the marine oyster Pinctada maxima, used as a biomaterial in oral surgery, is implanted in human bone, new bone formation occurs, resulting in a tight welding of the bone to the nacre [16].
(14) Tensile strength, 0.2% proof stress, and percentage elongation of the welded bars were measured and compared with the corresponding values for the titanium bars as delivered and with those of brazed type-3 gold alloy bars of similar dimensions.
(15) It was proved in experiment that endothelium formation is more adequate in a vascular microsuture formed by laser welding than in the formed by the traditional thread method.
(16) 23.2% of patients with pneumoconiosis caused by electric-welding aerosol showed regress of pneumoconiosis in afterdust period.
(17) Results indicated that excellent welds can be obtained with very little loss of strength and ductility in the area of the weld joint.
(18) Dizziness, headaches, and weakness occurred among three men after short-term hydrocarbon exposure during improper welding procedures in a closed container.
(19) In periods of reconstruction of chemical enterprises, hazardous compounds concentrations may exceed MAC, they are also characterized by contamination of the skin with toxic substances, welding aerosols discharge into the working zone, and microclimate distabilization.
(20) A limited investigation was carried out of the use of glass and ceramic fibre products used as protection against welding 'batter' and oxyacetylene welding flame.