(1) In the first assay, we used a simple density separation technique to remove dense neutrophils (PMN) from suspensions of blood and of bone marrow cells prior to culture in semisolid agar.
(2) After 12 days, 100% of the cells terminally differentiate, and clonogenic assays in IL 3-containing semisolid media indicate that the whole population has irreversibly lost proliferative capability.
(3) Three short-term human melanoma cell lines were tested for sensitivity to human recombinant alpha-tumor necrosis factor (TNF) in a semisolid agar colony formation assay.
(4) A 2 h exposure to HIV-1 resulted in a progressive and significant reduction of viable CD34+ cell number in liquid cultures and of granulocyte-macrophage, erythroid and megakaryocytic progenitors in semisolid cultures.
(5) When SV-MSCs were cultured in semisolid medium, they formed colonies of blast-like cells that, when replated on plastic, resumed adherent growth.
(6) The effects of transforming growth factor beta 3 (TGF-beta 3) on growth in semisolid cultures of enriched hematopoietic progenitors derived from normal human marrow and blood were evaluated.
(7) A culture system of semisolid medium was able to detect colony-forming units of chondrocytes.
(8) The expression of HLA-DR antigenic determinants on human hematopoietic progenitor cells (HPC) capable of differentiating into mature blood cells, as determined in semisolid cultures, has been demonstrated previously (3-7).
(9) Their B cells also have a characteristically low cloning efficiency in semisolid agar cultures, where LPS does not seem to be required.
(10) Colony-Stimulating Factor (CSF) production by peripheral blood leukocytes of renal transplant recipients was assayed using semisolid agar culture.
(11) on the basis of semisolid motility and ornithine decarboxylase tests.
(12) A transformed cystinotic cell line which was recovered from the crisis stage was indistinguishable from its transformed precrisis parental cell strain in growth rate in media containing either 1% or 10% serum, cloning efficiency on plastic, in semisolid media, or upon confluent monolayers of normal skin fibroblasts, expression of SV40 T antigen, or production of virus.
(13) After gel filtration, the 30-kDa activity stimulated the growth of very large colonies in semisolid medium consisting mainly of granulocytes with the remainder being macrophages.
(14) Single cell cloning of FD-TCL cells in semisolid medium required the addition of exogenous conditioned medium.
(15) The influence of lithium chloride on the proliferation of normal granulocyte-macrophage progenitor cells (CFU-GM) and clonogenic blasts (CFU-L) from patients with acute myeloid leukaemia in the semisolid cultures in vitro was investigated.
(16) The expression of EBNA-1, EBNA-2,EBNA-3A,EBNA-Lp or LMP caused shortening of doubling time, increased saturation cell density, reduced serum dependence, anchorage-independent growth in semisolid agar and activation of c-myc.
(17) Comparative studies of clonogenic ability of twenty four lung cancer samples have been performed in semisolid agar in vitro and in diffusion chambers in vivo.
(18) Semisolid cloning systems are now available to detect the specific progenitor cells of neutrophilmacrophages, eosinophils, megakaryocytes and erythroid cells.
(19) Microplaque formation is rapid, reproducible, and easily quantitated, occurs at temperatures ranging from 33 to 40 degrees C, and does not require a semisolid overlay.
(20) Organisms grown in a liquid overlay on a semisolid slant (biphasic medium) showed slow logarithmic growth and the presence of chromatoid material.
Solid
Definition:
(a.) Having the constituent parts so compact, or so firmly adhering, as to resist the impression or penetration of other bodies; having a fixed form; hard; firm; compact; -- opposed to fluid and liquid or to plastic, like clay, or to incompact, like sand.
(a.) Not hollow; full of matter; as, a solid globe or cone, as distinguished from a hollow one; not spongy; dense; hence, sometimes, heavy.
(a.) Having all the geometrical dimensions; cubic; as, a solid foot contains 1,728 solid inches.
(a.) Firm; compact; strong; stable; unyielding; as, a solid pier; a solid pile; a solid wall.
(a.) Applied to a compound word whose parts are closely united and form an unbroken word; -- opposed to hyphened.
(a.) Fig.: Worthy of credit, trust, or esteem; substantial, as opposed to frivolous or fallacious; weighty; firm; strong; valid; just; genuine.
(a.) Sound; not weakly; as, a solid constitution of body.
(a.) Of a fleshy, uniform, undivided substance, as a bulb or root; not spongy or hollow within, as a stem.
(a.) Impenetrable; resisting or excluding any other material particle or atom from any given portion of space; -- applied to the supposed ultimate particles of matter.
(a.) Not having the lines separated by leads; not open.
(a.) United; without division; unanimous; as, the delegation is solid for a candidate.
(n.) A substance that is held in a fixed form by cohesion among its particles; a substance not fluid.
(n.) A magnitude which has length, breadth, and thickness; a part of space bounded on all sides.
Example Sentences:
(1) An association of cyclophosphamide, fluorouracil and methotrexate already employed with success against solid tumours in other sites was used in the treatment of 62 patients with advanced tumours of the head and neck.
(2) The sensitivity of 75 non-CNS solid tumors to mismatched dsRNA was compared to the high-grade astrocytomas in the HTCA.
(3) (2) The treated animals ingested less liquid and solid food than controls.
(4) The peptides, which were synthesized using a FMOC solid phase procedure and purified by HPLC, consisted of residues 6-25 from the putative aqueous domain, residues 22-35, which overlaps the putative aqueous and transmembrane domains, and residues 1-38 and 1-40 representing nearly the full length of beta-AP.
(5) We describe an enzymatic fluorometric method for determining glucose concentrations in blood samples by analysis on a semi-solid surface (silicone-rubber pads).
(6) Of all solid tumors only nine occurred in relapse-free patients.
(7) It also showed weak inhibition of the solid type of Ehrlich carcinoma and prolonged the survival period of mice inoculated with L-1210 cells.
(8) Hybridomas were selected on the basis of solid-phase reactivity with the purified native A transferase, cell immunofluorescence and immunoprecipitation of transferase activity, and absence of reactivity with blood group ABH carbohydrate determinants.
(9) The principle of the liquid and solid two-phase radioimmunoassay and its application to measuring the concentrations of triiodothyronine and thyroxine of human serum in a single sample at the same time are described in this paper.
(10) Recently the presence of a coating inhibitory factor was described in human tears which can prevent the binding of proteins to a solid phase.
(11) We therefore conclude that the protective effect displayed by solid grafts might be a local process dependent on the release of diffusible trophic agents.
(12) As a strategy to reach hungry schoolchildren, and increase domestic food production, household incomes and food security in deprived communities, the GSFP has become a very popular programme with the Ghanaian public, and enjoys solid commitment from the government.
(13) The 68-kDa protein of B. bronchiseptica appeared to be the major protective antigen in B. bronchiseptica infection; however, isolated protein alone did not induce such a solid protection, as observed in a previous study after the application of an effective whole cell vaccine.
(14) The median age of patients with bacteremia of unknown origin was 65 years, and their most common underlying disorders were solid malignancy (28% of patients) and diabetes mellitus (18%).
(15) The free energy of activation showed a high negative correlation (r = -0.904, r2 = 0.817) with the percentage of virus adsorption to the solids tested.
(16) It was found that the use of a pH 9.6 buffer during the coating of ELISA plates led to the dissociation of virions into subunits which bound preferentially to the solid phase.
(17) You can tell them that Deutsche Bank remains absolutely rock solid, given our strong capital and risk position.
(18) A solid-phase microtiter assay was developed to investigate the binding properties of the vitronectin receptor.