(a.) Of or pertaining to old age; proceeding from, or characteristic of, old age; affected with the infirmities of old age; as, senile weakness.
Example Sentences:
(1) Hyperopia was more common in younger persons, but senile cataract, macular degeneration and palpebral dermatochalasis or blepharochalasis were more common in older persons.
(2) Mucosal drying medications and senile salivary gland atrophy seemed to contribute to the high frequency of sicca in this population with a lesser proportion of the subjects demonstrating previously undiagnosed Sjögren's and possible Sjögren's syndrome.
(3) Key findings include a progressive degeneration of these cholinergic neurons characterized by the formation of immunoreactively atypical NFT, the loss of intraneuronal lipofuscin, a lack of senile plaque and beta-amyloid deposition within the basal forebrain, and end-stage gliosis without residual extracellular NFT.
(4) This finding is consistent with the hypothesis that the majority of deaths attributed to presenile dementia and the majority of deaths from senile dementia are the result of the same disease entity.
(5) Diagnoses like neuroses, alcoholism, and senile dementia produced many visits by few patients.
(6) Her mother had only senile pigmented modification of the fundus and her three daughters had mild macular pigmented changes, like "salt and pepper."
(7) The reduced effectiveness of protection by antibody against viruses which had caused influenza disease 20--30 years ago was conducive to the spread of influenza Al cases among middle-aged and senile population.
(8) Since the detailed molecular events leading to the formation of amyloid-containing senile plaques of the Alzheimer's disease (AD) brain are incompletely understood, the present studies were undertaken to address this issue using a combination of molecular and cytochemical approaches.
(9) Recently in senile dementia of Alzheimer type, neuronal loss of cholinergic neurons in the substantia innominata is described.
(10) Whereas markedly high values of 1, 25-(OH)2D in plasma were found in some cases of primary hyperparathyroidism with prominent bone resorption, relatively low values were seen in some patients with chronic renal failure, senile osteoporosis, osteomalacia and hypercalcemia due to bone metastasis.
(11) The ultrastructure of the water-clear cells of the parathyroid glands in the starved adult and senile animals almost resembled that of the control adult and senile animals.
(12) The study of the drugs effective in the treatment of cognitive deficits and memory loss associated with senile dementia of the Alzheimer's type--tacrine and amiridin, acetylcholinesterase inhibitor physostigmine and nootrop piracetam on uptake of 3H-serotonin (3H-5-HT), 3H-adrenaline (3H-AD), 3H-noradrenaline (3H-HA), 2H-dopamine (3H-DA), 3H-gamma-aminobutyric acid (3H-GABA), 3H-glutamic acid (3H-GLU), 3H-aspartic acid (3H-ASP) and 3H-glycine (3H-GLI) showed that tacrine and amiridin (5 x 10(-5) M) statistically significantly (P less than 0.05) inhibited the uptake of 3H-DA and 3H-5-HT.
(13) The results are as follows: The neurites of senile DRG cells appeared 7 days later than the neurites of neonatal DRG cells.
(14) Although a trend was observed for TMA-DPH mobility to parallel histopathologic severity in hippocampal specimens, the biophysical changes did not appear to reflect a loss of neuronal membranes relative to glial membranes or the presence of senile plaques or neurofibrillary tangles.
(15) Corticotropin-releasing hormone-immunoreactivity (CRH-IR) and CRH receptors (binding capacity and affinity) were measured in postmortem cortical areas from depressed subjects, two groups of senile dementia of the Alzheimer type (SDAT), and age-, sex-, and postmortem-delay-matched controls.
(16) Anti-beta-peptide stained cerebrovascular and plaque core amyloid in all AD cases as well as cerebrovascular amyloid and senile plaque core amyloid in five elderly CJD cases.
(17) Senile dementia and admission other than from the patient's own home, were factors associated with a poorer long term outcome.
(18) In this study 40 fragments of human skin from 4 groups were included: children, adults, aged people with lesions of senile keratosis and without lesions of senile keratosis.
(19) To examine the efficacy of cholinergic enhancement in senile dementia of the Alzheimer type (SDAT), oral physostigmine was given to eight patients in a cross-over trial of three dose levels and a matching placebo.
(20) Here the presence and distribution within senile plaques of various epitopes of the beta-amyloid precursor protein (APP) are compared with the distribution of A beta P itself and markers for plaque neurites.
Senior
Definition:
(a.) More advanced than another in age; prior in age; elder; hence, more advanced in dignity, rank, or office; superior; as, senior member; senior counsel.
(a.) Belonging to the final year of the regular course in American colleges, or in professional schools.
(n.) A person who is older than another; one more advanced in life.
(n.) One older in office, or whose entrance upon office was anterior to that of another; one prior in grade.
(n.) An aged person; an older.
(n.) One in the fourth or final year of his collegiate course at an American college; -- originally called senior sophister; also, one in the last year of the course at a professional schools or at a seminary.
Example Sentences:
(1) Brown's model, which goes far further than those from any other senior Labour figure, and the modest new income tax powers for Holyrood devised when he was prime minister, edge the party much closer to the quasi-federal plans championed by the Liberal Democrats.
(2) Faisal Abu Shahla, a senior official in Fatah, an organisation responsible for a good deal of repression of its own when it was in power, accuses Hamas of holding 700 political prisoners in Gaza as part of a broad campaign to suppress dissent.
(3) Mike Enzi of Wyoming A senior senator from Wyoming, Enzi worked for the Department of Interior and the private Black Hills Corporation before being elected to Congress.
(4) "Especially at a time when they are turning down voluntary requests and securing the positions of senior managers."
(5) A Palestinian delegation was to hold truce talks on Sunday in Cairo with senior US and Egyptian officials, but Israel has said it sees no point in sending its negotiators to the meeting, citing what it says are Hamas breaches of previous agreed truces.
(6) Also, it is often the case that trustees or senior leadership are in said positions because they have personal relationships with the founder.
(7) His senior role in the Popalzai tribe and his chairmanship since 2005 of Kandahar provincial council bolstered his reputation as an Asian version of a mafia don.
(8) It is understood that Cooper rejected pressure from senior Labour figures last week for both her and Liz Kendall to drop out and leave the way clear for Burnham to contest Corbyn alone.
(9) They are saying they have paid with their blood and they do not want to retreat," said Saad el-Hosseini, a senior Brotherhood politician.
(10) "We won't cancel any of our agreements," a senior Israeli diplomatic official told reporters.
(11) A senior shadow minister, who has not been named by the Telegraph in its exposé of MPs' expenses , was yesterday asked by county councillors not to campaign for next month's local elections.
(12) Sir James Crosby, the ITV senior independent non-executive director, explained why the board had opted to retain Grade's services for an extra year: "It was the unanimous view of ITV's independent non-executive directors that it would be in the best interests of the company and its shareholders to ask Michael to extend his time as executive chairman.
(13) Lisette van Vliet, a senior policy adviser to the Health and Environment Alliance, blamed pressure from the UK and German ministries and industry for delaying public protection from chronic diseases and environmental damage.
(14) "Android’s gain came mainly at the expense of BlackBerry, which saw its global smartphone share dip from 4 percent to 1 percent in the past year due to a weak line-up of BB10 devices," said Strategy Analytics' senior analyst Scott Bicheno.
(15) Sajeda Amin is a senior associate at the Population Council .
(16) Tim Moore, senior economist at Markit, said: "Construction is no longer the weakest link in the UK economy.
(17) One hundred cases of histologically proven corneal and conjunctival tumours were extracted from the records at the Princess Alexandra Hospital and from the senior author's private practice in the last ten years.
(18) The Dacre review panel, which included Sir Joseph Pilling, a retired senior civil servant, and the historian Prof Sir David Cannadine, said Britain now had one of the "less liberal" regimes in Europe for access to confidential government papers and that reform was needed to restore some trust between politicians and people.
(19) Senior sources said on Monday that the vacancies had left it in effect rudderless, and unable to introduce any significant reforms.
(20) Top 10 Arpad Cseh Senior investment director, UBS Alice La Trobe Weston Executive director, head of European credit research, MSIM Morgan Stanley Katie Garrett Executive director, senior engineer, Goldman Sachs Alix Ainsley, Charlotte Cherry H R director, group operations (job share), Lloyds Banking Group Matt Dawson Director for business development, The Instant Group Angela Kitching, Hannah Pearce Head of external affairs (job share), Age UK Morwen Williams Head of newsgathering operations, BBC Georgina Faulkner Head of Sky multisports, Sky Maggie Stilwell Managing partner for talent, UK & Ireland, EY Sarah Moore Partner, PwC