(a.) Grave in manner or disposition; earnest; thoughtful; solemn; not light, gay, or volatile.
(a.) Really intending what is said; being in earnest; not jesting or deceiving.
(a.) Important; weighty; not trifling; grave.
(a.) Hence, giving rise to apprehension; attended with danger; as, a serious injury.
Example Sentences:
(1) This should not be a serious limitation to the application of the RIA in the detection of venous thrombosis.
(2) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(3) "There is a serious risk that a deal will be agreed between rich countries and tax havens that would leave poor countries out in the cold.
(4) Confidence is the major prerequisite for a doctor to be able to help his seriously ill patient.
(5) No report can be taken seriously if its authors weren’t even in Yemen to conduct investigations.” The UN team was not given permission to enter the country.
(6) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
(7) Vancomycin is the antibiotic of choice for serious MRSA infections; PRPs and cephalosporins generally are not effective.
(8) An age- and education-matched group of women with no family history of FXS was asked to predict the seriousness of problems they might encounter were they to bear a child with a handicapping condition.
(9) The most serious complications following operative treatment are retained bile duct calculi (2.8%), wound infection and biliary fistulae.
(10) Guardian Australia reported last week that morale at the national laboratory had fallen dramatically, with one in three staff “seriously considering” leaving their jobs in the wake of the cuts.
(11) In case of biliary and pancreatic duct obstruction with pure pancreatic reflux, both oedema and inflammatory infiltrations were evident, whereas, in the presence of biliary reflux too, more serious histological features were detected.
(12) Autopsy revealed serious somatic diseases (stenosis of the ileum in two cases and brain tumor in one); their symptoms had been largely overlapped by those of anorexia nervosa.
(13) The above treatment is tolerated well and no serious side effects have been observed.
(14) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(15) Earlier recognition of foul-smelling mucoid discharge on the IUD tail, or abnormal bleeding, or both, as a sign of early pelvic infection, followed by removal of the IUD and institution of appropriate antibiotic therapy, might prevent the more serious sequelae of pelvic inflammation.
(16) Left ventricular rupture is a serious complication of mitral valve replacement.
(17) Other serious complications were reservoir perforation during catheterisation in 3 and development of stones in the reservoir in 2 patients.
(18) For application to mammalian cells, however, two serious problems require resolution: (1), correction of TPP+ binding to intracellular constituents and (2), estimation of the considerable TPP+ accumulation in mitochondria.
(19) At least 1 episode of serious infection occurred in 34 of the 60 adult patients and 25 of the 30 children.
(20) These high Danish rates seem to reflect the true prevalence and incidence in the less serious types of progressive muscular dystrophy, probably because the Danish health system with free medical care and easy access to specialized hospital departments makes it possible to identify all cases of progressive muscular dystrophy.
Significant
Definition:
(a.) Fitted or designed to signify or make known somethingl having a meaning; standing as a sign or token; expressive or suggestive; as, a significant word or sound; a significant look.
(a.) Deserving to be considered; important; momentous; as, a significant event.
(n.) That which has significance; a sign; a token; a symbol.
Example Sentences:
(1) Once treatment began, no significant changes occurred in Group 1, but both PRA and A2 rose significantly in Groups 2 and 3.
(2) However, patients with GGBHS were significantly older (P less than .05).
(3) In each sheep there was a significant negative correlation between the glucose and corticosteroid concentrations in both maternal and fetal plasma, and there were positive correlations between the maternal and fetal plasma concentrations of glucose, and between the glucose and fructose concentrations of fetal plasma.
(4) Such a decrease significantly biased survival (p = 0.001).
(5) This may have significant consequences for people’s health.” However, Prof Peter Weissberg, medical director of the British Heart Foundation, which funded the work, said medical journals could no longer be relied on to be unbiased.
(6) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(7) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(8) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(9) Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate.
(10) In some other countries the patient-to-nurse ratio was significantly smaller.
(11) The findings indicate that there is still a significant incongruence between the value structure of most family practice units and that of their institutions but that many family practice units are beginning to achieve parity of promotion and tenure with other departments in their institutions.
(12) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(13) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(14) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(15) During control, no significant difference between systolic fluctuation (delta Pa) and pleural swings (delta Ppl) was found.
(16) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).
(17) Both lymph flow from cannulated pancreatico-duodenal lymphatics and intralymphatic pressure in the non-transected ones increased significantly.
(18) We conclude that the priming effect is not a clinically significant phenomenon during natural pollen exposure in allergic rhinitis patients.
(19) This study examined the [3H]5-HT-releasing properties of 3,4-methylenedioxymethamphetamine (MDMA) and related agents, all of which cause significant release of [3H]5-HT from rat brain synaptosomes.
(20) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).