(a.) Grave in manner or disposition; earnest; thoughtful; solemn; not light, gay, or volatile.
(a.) Really intending what is said; being in earnest; not jesting or deceiving.
(a.) Important; weighty; not trifling; grave.
(a.) Hence, giving rise to apprehension; attended with danger; as, a serious injury.
Example Sentences:
(1) This should not be a serious limitation to the application of the RIA in the detection of venous thrombosis.
(2) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(3) "There is a serious risk that a deal will be agreed between rich countries and tax havens that would leave poor countries out in the cold.
(4) Confidence is the major prerequisite for a doctor to be able to help his seriously ill patient.
(5) No report can be taken seriously if its authors weren’t even in Yemen to conduct investigations.” The UN team was not given permission to enter the country.
(6) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
(7) Vancomycin is the antibiotic of choice for serious MRSA infections; PRPs and cephalosporins generally are not effective.
(8) An age- and education-matched group of women with no family history of FXS was asked to predict the seriousness of problems they might encounter were they to bear a child with a handicapping condition.
(9) The most serious complications following operative treatment are retained bile duct calculi (2.8%), wound infection and biliary fistulae.
(10) Guardian Australia reported last week that morale at the national laboratory had fallen dramatically, with one in three staff “seriously considering” leaving their jobs in the wake of the cuts.
(11) In case of biliary and pancreatic duct obstruction with pure pancreatic reflux, both oedema and inflammatory infiltrations were evident, whereas, in the presence of biliary reflux too, more serious histological features were detected.
(12) Autopsy revealed serious somatic diseases (stenosis of the ileum in two cases and brain tumor in one); their symptoms had been largely overlapped by those of anorexia nervosa.
(13) The above treatment is tolerated well and no serious side effects have been observed.
(14) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(15) Earlier recognition of foul-smelling mucoid discharge on the IUD tail, or abnormal bleeding, or both, as a sign of early pelvic infection, followed by removal of the IUD and institution of appropriate antibiotic therapy, might prevent the more serious sequelae of pelvic inflammation.
(16) Left ventricular rupture is a serious complication of mitral valve replacement.
(17) Other serious complications were reservoir perforation during catheterisation in 3 and development of stones in the reservoir in 2 patients.
(18) For application to mammalian cells, however, two serious problems require resolution: (1), correction of TPP+ binding to intracellular constituents and (2), estimation of the considerable TPP+ accumulation in mitochondria.
(19) At least 1 episode of serious infection occurred in 34 of the 60 adult patients and 25 of the 30 children.
(20) These high Danish rates seem to reflect the true prevalence and incidence in the less serious types of progressive muscular dystrophy, probably because the Danish health system with free medical care and easy access to specialized hospital departments makes it possible to identify all cases of progressive muscular dystrophy.
Weighty
Definition:
(superl.) Having weight; heavy; ponderous; as, a weighty body.
(superl.) Adapted to turn the balance in the mind, or to convince; important; forcible; serious; momentous.
(superl.) Rigorous; severe; afflictive.
Example Sentences:
(1) It is appropriate that AIDS be responded to as a crisis, but we also have a weighty, preexisting set of long-standing and equally lethal health and social ills.
(2) Weighty stuff, but critics hailed the show as the neurotic standup’s best in years.
(3) They imply that it is a matter of weighty regret that things have now reached a pass where their only conscionable option is to declare "thus far and no further".
(4) 4S, 5S, AND 18S + 28S RNA from the newt Taricha granulosa granulosa were iodinated in vitro with carrier-free 125I and hybridized to the denatured chromosomes of Taricha granulosa and Batrachoseps weighti.
(5) We'll be here until then and beyond, sharing every rumour nugget, insightful news line and weighty analysis we can muster.
(6) Little ones might freak out a bit at the wax characters and the gloomy dark but this is a fun way to bring a fairly weighty school text to life.
(7) In contrast, D changed from left weightiness to symmetry, coinciding with improvement but not with deterioration, With reference to the latter findings we discuss the possibility of a particular mode of cerebral lateralization predisposing to endogenous depression.
(8) The DPA is a weighty US drug policy reform NGO that can boast tycoons such as George Soros and Richard Branson and celebrities including Sting on its board of directors.
(9) Then there were the imported dramas broadcast because they were weighty, such as 1984's Heimat , an enthralling dramatisation of ordinary lives in 20th-century Germany.
(10) At the time of his resignation he had far more weighty matters filling his in-tray than the NRB case, not least a probe into alleged corruption among some of Boris Yeltsin's close relatives.
(11) Brennan bridles at that, saying it would be "a very weighty decision in terms of declassifying that report."
(12) In the Nederlandsch Tijdschrift voor Geneeskunde the last-mentioned aspect appears to have been very weighty, especially in the beginning.
(13) Weighty, expensive impact reports sit hidden deep within websites (or worse, annual reports), while the public remains oblivious to what happens to donations.
(14) They're running almost entirely on biscuits and cans of Red Bull, kept awake by a mix of jokes, weighty debate, and general good humour.
(15) It's an extra nerdy and intelligent version too, with tactical jedi Jonathan Wilson and his young apprentic Zonal Marking's Michael Cox there to provide the yuks and giggles as myself and James Richardson analyse the weighty football issues of the day to within an inch of their lives.
(16) The world will long remember their son Edward as the heir to a weighty legacy; a champion for those who had none; the soul of the Democratic party; and the lion of the US Senate – a man whose name graces nearly one thousand laws, and who penned more than 300 himself.
(17) It was the world of John Smith, razor-sharp debating, forensic examination of weighty issues and Gaitskellite intrigues.
(18) A comparison between the activity of the two hands yielded a pronounced left-weightiness of object-focused, continuous body-focused and discrete body-focused movements in contrast to findings on normal persons.
(19) The chancellor demanded that officials develop weighty evidence about whether or not the new 50p rate was working.
(20) The science report is the first of three major IPCC reports this year; similarly weighty analysis of the impact and possible solutions will follow in April and May respectively.