(superl.) Having a very thin edge or fine point; of a nature to cut or pierce easily; not blunt or dull; keen.
(superl.) Terminating in a point or edge; not obtuse or rounded; somewhat pointed or edged; peaked or ridged; as, a sharp hill; sharp features.
(superl.) Affecting the sense as if pointed or cutting, keen, penetrating, acute: to the taste or smell, pungent, acid, sour, as ammonia has a sharp taste and odor; to the hearing, piercing, shrill, as a sharp sound or voice; to the eye, instantaneously brilliant, dazzling, as a sharp flash.
(superl.) High in pitch; acute; as, a sharp note or tone.
(superl.) Raised a semitone in pitch; as, C sharp (C/), which is a half step, or semitone, higher than C.
(superl.) So high as to be out of tune, or above true pitch; as, the tone is sharp; that instrument is sharp. Opposed in all these senses to flat.
(superl.) Very trying to the feelings; piercing; keen; severe; painful; distressing; as, sharp pain, weather; a sharp and frosty air.
(superl.) Cutting in language or import; biting; sarcastic; cruel; harsh; rigorous; severe; as, a sharp rebuke.
(superl.) Of keen perception; quick to discern or distinguish; having nice discrimination; acute; penetrating; sagacious; clever; as, a sharp eye; sharp sight, hearing, or judgment.
(superl.) Eager in pursuit; keen in quest; impatient for gratification; keen; as, a sharp appetite.
(superl.) Keenly or unduly attentive to one's own interest; close and exact in dealing; shrewd; as, a sharp dealer; a sharp customer.
(superl.) Composed of hard, angular grains; gritty; as, sharp sand.
(superl.) Steep; precipitous; abrupt; as, a sharp ascent or descent; a sharp turn or curve.
(superl.) Uttered in a whisper, or with the breath alone, without voice, as certain consonants, such as p, k, t, f; surd; nonvocal; aspirated.
(adv.) To a point or edge; piercingly; eagerly; sharply.
(adv.) Precisely; exactly; as, we shall start at ten o'clock sharp.
(n.) A sharp tool or weapon.
(n.) The character [/] used to indicate that the note before which it is placed is to be raised a half step, or semitone, in pitch.
(n.) A sharp tone or note.
(n.) A portion of a stream where the water runs very rapidly.
(n.) A sewing needle having a very slender point; a needle of the most pointed of the three grades, blunts, betweens, and sharps.
(n.) Same as Middlings, 1.
(n.) An expert.
(v. t.) To sharpen.
(v. t.) To raise above the proper pitch; to elevate the tone of; especially, to raise a half step, or semitone, above the natural tone.
(v. i.) To play tricks in bargaining; to act the sharper.
(v. i.) To sing above the proper pitch.
Example Sentences:
(1) Basal 20 alpha DHP levels remained low until a sharp rise at mid pro-oestrus.
(2) Whole-virus vaccines prepared by Merck Sharp and Dohme (West Point, Pa.) and Merrell-National Laboratories (Cincinnati, Ohio) and subunit vaccines prepared by Parke, Davis and Company (Detroit, Mich.) and Wyeth Laboratories (Philadelphia, Pa.) were given intramuscularly in concentrations of 800, 400, or 200 chick cell-agglutinating units per dose.
(3) Gonadectomy of females was accompanied by changes in the activity of individual HAS links in different direction--some reduction of ACTH in the hypophysis, a sharp and significant fall of the peripheral blood glucocorticoid level and a marked significant elevation of hydrococortisone production in the adrenal cortex in vitro.
(4) The University of the Arts London and Sunderland, Sheffield Hallam, Manchester Met and Leeds Met university have also experienced sharp declines in applications.
(5) A sharp decrease in oxygen uptake occurred in Neurospora crassa cells that were transferred from 30 degrees C to 45 degrees C, and the respiration that resumed later at 45 degrees C was cyanide-insensitive.
(6) In contrast to findings in the rat and dog, no sharp drop but a gradual fall in CLi was observed at decreasing FENa values down to 0.02%.
(7) A more specific differentiation, as indicated by the sharp increase in GAD levels which was concurrent with an increase in interneuronal contacts, lagged behind the initial growth.
(8) It appears that the decline in plasma IGF-I lags considerably behind the sharp fall in plasma GH levels and expression of hepatic IGF-I mRNA.
(9) Supplementation of Mg resulted in a sharp increase in serum PTH level with a rapid disappearance of the dissociation between the two immunoassays of PTH.
(10) A.CA animals were extremely susceptible, showing a sharp and sustained increase in parasitemia starting on day 12, followed by death no later than day 15 post-inoculation.
(11) There was a sharp transition with actin nearly saturated with S1: when the S1 to actin ratio was low, the kinetics were fast (K1 greater than 300 microM, k2 greater than 40 s-1); when it was high, they were slow (K1 = 14 microM, k2 = 2 s-1).
(12) Low calcium causes an increase in optimum frequency, a decrease in current threshold, and an increase in sharpness of tuning in both real axons and axons computed according to the Hodgkin-Huxley formulation; high calcium causes opposite effects.
(13) The Tea Party movement has turned climate denial into a litmus test of conservative credentials – and that has made climate change one of the most sharp divisions between Obama and Romney.
(14) The presence in lamprey kidney of a loop which is similar to Henle's loop in mammals and birds indicates that the development of the system of osmotic concentration conditioned by the formation in the kidney of the medulla and from a sharp increase in renal arterial blood supply.
(15) There is no longer a sharp dividing line between working and rentiering.
(16) We are going to see a sharp fall unless sellers hold the sector up by making aggressive offers.
(17) A sharp increase in the intensity of lipids biochemiluminiscence and decrease in the tissue homogenates biochemiluminiscence were observed during the period of progressive tumour growth on the 6-8 days following introduction of the virus.
(18) By no means is this a new theme, but it has taken on an added sharpness and urgency after the conferences.
(19) The blood lymphocytes were small with scanty cytoplasm, densely condensed nuclear chromatin, and deep clefts originating in sharp angles from the nuclear surface.
(20) In sharp contrast, the coverage provided by the various mainstream news channels and newspapers not only seems – with some exceptions – unresponsive and stilted, but often non-existent.
Sour
Definition:
(superl.) Having an acid or sharp, biting taste, like vinegar, and the juices of most unripe fruits; acid; tart.
(superl.) Changed, as by keeping, so as to be acid, rancid, or musty, turned.
(superl.) Disagreeable; unpleasant; hence; cross; crabbed; peevish; morose; as, a man of a sour temper; a sour reply.
(superl.) Afflictive; painful.
(superl.) Cold and unproductive; as, sour land; a sour marsh.
(n.) A sour or acid substance; whatever produces a painful effect.
(v. t.) To cause to become sour; to cause to turn from sweet to sour; as, exposure to the air sours many substances.
(v. t.) To make cold and unproductive, as soil.
(v. t.) To make unhappy, uneasy, or less agreeable.
(v. t.) To cause or permit to become harsh or unkindly.
(v. t.) To macerate, and render fit for plaster or mortar; as, to sour lime for business purposes.
(v. i.) To become sour; to turn from sweet to sour; as, milk soon sours in hot weather; a kind temper sometimes sours in adversity.
Example Sentences:
(1) The sensitivity of the taste system to the various qualities was, in decreasing order, salty, sweet, sour, and bitter.
(2) The parotid saliva of the caries-rampant group showed a significantly higher level of anodemigrating proteins, predominantly isoamylases, and a significantly lower level of cathode-migrating proteins than that of the caries-resistant group in both paraffin-stimulated and sour lemon-stimulated salivary flows.
(3) But the cocktails take centre stage and are like drinkable pieces of art – try the margarita or the pisco sour.
(4) The munching, and some data crunching, produced firm statistical findings ("The flavour cowy was correlated with age and sourness, but was not correlated to any other flavours or tastes").
(5) A shame such a landmark achievement was soured by Allam refusing to talk to the local council over a potential stadium expansion and trying to change the club’s name to Hull Tigers, which many fans vehemently oppose.
(6) Admittedly, there has been a bit of sour grapes in the English response to the success of Dempsey et al, and no doubt we will be treading those grapes into wine and drinking ourselves into oblivion if Team USA get much further – they are, as today's typically excitable NY Daily News front page informs us, now just "four wins from glory" .
(7) Kaesong, which facilitated nearly $2bn a year in cross-border trade, had been the last joint project left as relations between the two Koreas soured over the past five years.
(8) The UK remains one of the most diligent enforcers of convention rights, but it appears to have soured into one of the least appreciative national constituencies.
(9) Before the adenosine test, the perception of sourness was tested similarly with six concentrations of citric acid (1-100 mM).
(10) Sour taste stimuli (weak acids) decreased outward K+ currents and slightly reduced inward currents; bitter taste stimuli (quinine) reduced inward currents to a greater extent than outward currents.
(11) If i remember correctly, a third of the milk was turned sour, a Russian delicacy'.
(12) Instead, the different taste qualities--sweet, sour, salty, bitter--are subserved by different mechanisms.
(13) "They are taking a mixed strategy, which I would call the sweet and sour approach," Peter Beck, research fellow at Stanford University and a specialist on Korean affairs, told Reuters.
(14) On average, monosodium glutamate and seltzer, which mongrel dogs do not normally encounter in their diets, produced lower gastric acid secretion and pancreatic polypeptide release than sweet, sour, salty, bitter, and meaty tastes.
(15) Ruth Joseph and Sarah Nathan's crumbly little almond and lemon tarts are the perfect example of its charms, to my mind – not too sweet, not too sour, just intensely, deliciously zesty.
(16) Behavior of Staphylococcus aureus strains 100-A, 196-E, 254, 473, 505, and 521 in sweet (18 to 80% milk fat) and neutralized sour cream was studied.
(17) "That was for the players and their families," said Benítez, the implication being why should he risk souring the atmosphere by simply joining in?
(18) If the maximum investment choice is not taken, and NHS performance turns sour in future years, Stevens will be able to say, “I told you so”.
(19) They worked together at Porto, Chelsea and Internazionale but the relationship has soured.
(20) Suu Kyi's relationship with the generals has reportedly turned sour again In her tireless efforts to secure cooperation from the military, Suu Kyi has repeatedly expressed her appreciation, respect and “genuine” affection for the Tatmadaw (feudal military), which her father founded under Japan’s fascist patronage in December 1942, much to the dismay of many minorities who have borne the brunt of the organisation’s ruthless policies.