(n.) A reaping instrument consisting of a steel blade curved into the form of a hook, and having a handle fitted on a tang. The sickle has one side of the blade notched, so as always to sharpen with a serrated edge. Cf. Reaping hook, under Reap.
(n.) A group of stars in the constellation Leo. See Illust. of Leo.
Example Sentences:
(1) In addition, congenital anemias such as sickle cell disease can impact on the health of the mother and fetus.
(2) Sickle and normal discocytes both showed membrane elasticity with reversion to original cell shape following release of the cell from its aspirated position at the pipette tip.
(3) Fourier transform infrared (FTIR) spectroscopy was used to examine the effect of oxysterol insertion into normal and sickle RBC membranes and the total lipid extracts of the membranes.
(4) The initial screening failed to detect sickle cell anemia in 4 infants, but the hemoglobinopathy in 3 of these infants was diagnosed correctly by routine retesting of those with suspected sickle cell trait.
(5) The sources were two adolescent patients with sickle cell disease and aplastic crisis who had unsuspected parvovirus infection.
(6) Thus, an abnormality of neutrophil oxidative metabolism cannot explain the propensity to bacterial infections in sickle cell disease.
(7) In order to examine sickle cell blood flow during MR imaging in vivo, laser-Doppler velocimetry was performed in normal control subjects and in sickle cell subjects before, during, and after MR imaging at 0.35 and 1.5 T. Mean blood flow and patterns of blood-flow variability were compared by two hematologists.
(8) Calcium-dependent ATPase, adenylate cyclase and phosphorylation of erythrocyte membrane proteins have been found abnormal in various conditions: hereditary spherocytosis, sickle-cell anemia, progressive muscular dystrophies, all of these disorders being associated with a decreased deformability of the erythrocyte.
(9) Sickle cell anemia and other hemoglobinopathies represent a major health problem in the United States.
(10) This suggests that there is little survival advantage or disadvantage in the combination of glucose-6-phosphate dehydrogenase deficiency and sickle cell anaemia.
(11) We present a boy with sickle cell glomerulopathy and FSGS who is younger than patients with similar findings reported previously.
(12) Disruption of normal blood flow patterns in the medulla with impairment of function of the loop of Henle (functional papillectomy), presumably because of sickling in the hyperosmolar and anoxic environment of the renal medulla, may mediate these abnormalities.
(13) A study was conducted in a sample of 140 children with sickle cell anemia to evaluate the relationship between hematological variables (%HbF, %HbA2, %Hb, and mean cell volume) and disease severity.
(14) These include diseases diagnosed by restriction-site variation, such as Duchenne's muscular dystrophy and sickle cell anemia, those due to a collection of known mutations, such as beta-thalassemia, and those due to gene deletion, such as alpha-thalassemia.
(15) You’d think Michael Foot himself was running, attending debates in a hammer and sickle-print donkey jacket, from the amount we’ve been talking about him.
(16) Although these diseases are routinely screened for at birth, there is no general strategy among district health authorities for sickle cell screening.
(17) When red cells were loaded with Ca2+ using Ionophore A23187, both normal and sickle red cells enhanced their phosphorylation and sickle red cells to a greater extent than normal red cells.
(18) Nearly all sickle cell anemia patients carried the beta S mutation on a chromosome with haplotype 19 (or Benin) and all had severe anemia with sickling complications.
(19) The agent 12C79 which increases the oxygen affinity of sickle cells in vivo and prevent HbS polymerization is in clinical development.
(20) The results indicated that sickle cell patients have significant psychosocial distress in the areas of employment and finances, sleeping and eating, and performance of normal daily activities.
Tickle
Definition:
(v. t.) To touch lightly, so as to produce a peculiar thrilling sensation, which commonly causes laughter, and a kind of spasm which become dengerous if too long protracted.
(v. t.) To please; to gratify; to make joyous.
(v. i.) To feel titillation.
(v. i.) To excite the sensation of titillation.
(a.) Ticklish; easily tickled.
(a.) Liable to change; uncertain; inconstant.
(a.) Wavering, or liable to waver and fall at the slightest touch; unstable; easily overthrown.
Example Sentences:
(1) The current script is still being tickled every day.
(2) However, nurturers of Britain’s nascent wine industry with an eye on an emerging market, where appreciation of wine is a status symbol, might hope that senior communist party palettes will have been tickled by the Ridgeview Grosvenor 2009, a sparking English wine originating in West Sussex.
(3) In man, lesions of the posterior columns cause an increase in pain, tickle, warmth and cold.
(4) "I'd be tickled to death if it would make 50 bushels (1.5 tonnes), if we don't have rain," he said.
(5) They remember his louche looseness with the facts , his willingness to invent stories of EU straight-banana absurdity to tickle the prejudices of his readers back home.
(6) "We got together in LA without her, just to see what we got, like we could seduce her in the process, come up with something that would tickle her ears and she'd go: 'Oh wow, you guys are really up to something good here'.
(7) Four profoundly hearing-impaired adults who did not meet current selection criteria for implantation at the University of Melbourne were each fitted with a wearable multichannel electrotactile speech processor (Tickle Talker).
(8) He was tickled, once, while walking through Greenwich Village, to see "a guy came along the street wearing a muscle T-shirt, very tight.
(9) The children were able to use tactile input to achieve higher scores on three speech feature subtests of the PLOTT test when using the Tickle Talker plus hearing aids as compared to hearing aids alone.
(10) Now, I love this sort of thing – it's my job to be tickled by it – but there comes a point when you finally have to ask, where is your movie, Mr Verbinski?
(11) The recording tickled him because it sounds nothing like a car, but exactly like the sound of a cow mooing.
(12) For myself, it’s not something I’ve been accustomed to experimenting with.” Spy review – uproarious Paul Feig comedy tickles SXSW Read more Feig wrote the part especially for Statham.
(13) Although the subjects' stimulations were unaffected by looking at the gestures, the tactual stimulus elicited a tickle sensation.
(14) As part of a larger subject group, four profoundly hearing-impaired children enrolled in a total communication educational program were fitted with the University of Melbourne's multichannel electrotactile speech processor (Tickle Talker).
(15) To study these, Ss rated perceived "tickle-strength" in situations where they were tickled: (a) with their eyes closed; (b) with their eyes open; (c) with their own arm doing the tickling, but being moved by someone else; (d) by themselves.
(16) Leat was also seen lifting up and touching young girls in the playground and tickling and cuddling pupils in class.
(17) We examined separately tickle perception and pleasure and anxiety during sexual sequence of 40 dermapathic (20 men and 22 women) and 39 normal subjects (20 men and 19 women) aged between 35 and 40 yr.
(18) Pregnancy leads to modifications in sensitivity to tickle, specifically with regard to the right half of the body and to some extent in body schema.
(19) "His promised new party is far from certain to get into parliament, but depending on how well it tickles the fancies of some of the more radical, marginalised, and disillusioned voters and non-voters, the so-called Mega party could have a huge impact on who forms the next government."
(20) The biological baseline here is usually the laughter caused by tickling, which most of us assume to be some simple form of reflex action.