(1) And we welcome the new minister of women's affairs, Doctor Sima Samar.
(2) A mucin preparation from a colonic adenocarcinoma was used to prepare monoclonal antibodies (MAbs) that reacted specifically either with normal adult small-intestine mucin antigen(s) (SIMA), or normal adult large-intestine mucin antigen(s) (LIMA).
(3) Only the SIMA epitope was sensitive to neuraminidase.
(4) In the BIMA group two pleural cavities, the SIMA group one pleural sac and the VS group none of the pleural cavities was entered.
(5) At the subcellular level, both anti-SIMA MAb showed reactivity typical of normal mucin, i.e., goblet cell and extracellular mucin.
(6) SIMA epitopes are thus markers of very early neoplastic change, whose expression correlates with malignant potential and may contribute to the accumulation of changes necessary for tumourigenesis.
(7) Inappropriate SIMA production was detected by either anti-SIMA MAb 4D3 or 4A1, even in 85% of early stage cancers.
(8) Inappropriate expression of SIMA epitopes was first detected in mucosa adjacent to minute microadenomas larger than three glands, and with increase in size, in increasing amounts within adenomas themselves, but not with microadenomas smaller than three glands or regions of flat mucosa free of adenomas.
(9) Comparison of the pre-operative data showed that patients who had a SIMA were similar to those who had a SVG except that they were older, had a more stable presentation and they had a higher incidence of myocardial infarction.
(10) We describe the production, immunochemical and immunohistochemical characterization of monoclonal antibodies (MAbs) raised against the oncofetal small intestinal mucin antigen (SIMA).
(11) A high rate of inappropriate SIMA expression was also detected in the perineoplastic transitional mucosa (88%, c.f.
(12) The previously reported hierarchy of four SIMA epitopes (5C5, 3D4, 4D3, 6C5) was also consistently observed in the adenoma-carcinoma sequence, and applied to (i) the order of epitope detection, (ii) the number of positive adenomas and (iii) extent of staining; (iv) the height in the crypt and (v) distance from the adenoma to which epitopes were expressed in perineoplastic mucosa.
(13) The colorectal adenoma-carcinoma sequence was examined in relation to the ectopic expression of the oncofoetal Small Intestinal Mucin Antigen (SIMA), to the development of morphologic changes in the adenoma and perineoplastic mucosa and to indices of malignant potential.
(14) The percentage of positive adenomas and reactivity scores for each anti-SIMA MAb correlated with increasing adenoma size, degree of dysplasia and growth pattern.
(15) Photograph: Sima Diab for the Guardian This article was amended on 22 June 2015 to change the description of Hungary’s government to “illiberal” to better reflect the regime in place.
(16) Photograph: Sima Diab for the Guardian While they wait for his call, everyone fears an attack from the police.
(17) Photograph: Sima Diab for the Guardian As the sun sets, huddle after huddle of Syrian refugees, travelling together for protection, edge north along the bends of the river.
(18) Small intestine mucin antigen (SIMA) is an oncofoetal antigen for the colon and is distinct from the normal large intestinal mucin antigen (LIMA).
(19) SIMA epitope expressed in mucosa adjacent to adenomas preceded changes in perineoplastic morphology, which progressed with adenoma growth to resemble transitional mucosa (TM) adjacent to cancers.
(20) In the control and gastric carcinoma groups, neither large intestinal mucin antigen (LIMA) nor small intestinal mucin antigen (SIMA) could be detected in the normal epithelium of gastric mucosa.
Soma
Definition:
(n.) The whole axial portion of an animal, including the head, neck, trunk, and tail.
Example Sentences:
(1) An initial complex-soma inflection was observed on the rising phase of the action potential of some cells.
(2) Axons emerge from proximal dendrites within 50 microns of the soma, and more rarely from the soma, in a tapering initial segment, commonly interrupted by one or two large swellings.
(3) In cat, DARPP-32-immunoreactive cell bodies identified as Müller cells were demonstrated in the inner nuclear layer (INL) with processes closely surrounding the cell soma of photoreceptors in the outer nuclear layer.
(4) Today the physician who treats women with emotional problems during menopause cannot function solely as a psychotherapist; he must deal with both their soma and psyche.
(5) For those synapses that were close to the soma the time constant for decay for the non-NMDA component, which was voltage insensitive, ranged from 4-8 ms. 7.
(6) We find that the labelled cell has a myelinated axon, but that the axon loses its myelin within 50 microns of the soma and has not yet been traced further.
(7) The soma of the injured neutron has a dense perinuclear ring of RNA.
(8) The effective electrical geometry under the conditions of control and 0.5 mM PNB sufficient to completely abolish the postsynaptic potential were determined from analyses of the membrane charging curves assuming the lumped-soma-short-cable model.
(9) Sequential recordings of spike amplitudes from the axon hillock, soma, and lateral dendrite suggest that the generator of the axotomy-induced component is localized to the normally passive soma and proximal dendrite.
(10) In order to determine whether there is a relationship between soma diameter and oxidative enzyme activity of alpha-motoneurons, we investigated the alpha-motoneurons innervating the different portions within a rat gluteus medius muscle.
(11) In oestrogen-treated preparations, tuberoinfundibular arcuate neurons responsive and unresponsive to accessory bulb stimulation could be distinguished by the frequency of successful antidromic propagation into the soma.
(12) These cells were also NSE positive and were characterized by the presence of soma action potentials.
(13) It is concluded that barium ions have at least 2 points of attack in the ganglion: 1, on the soma membrane of the neurones, and 2, on the presynaptic terminals controlling them.
(14) By the end of this period the neuronal soma and the proximal dendrites appeared mature in terms of both morphology and synaptic input.
(15) Although the globular bushy cell axons were not completely filled from the soma of origin to terminal fields in the contralateral brainstem, a number of consistent anatomical features were distinguished in the population.
(16) Approximately 85% of Na channels in the soma are essentially indistinguishable from those in the giant axon with regard to gating properties and sensitivity to tetrodotoxin or saxitoxin.
(17) In slices cut parallel to the pyramidal neurons (perpendicular to the brain surface) one can study chemosensitivity of the various parts of the dendritic tree and the soma.
(18) It has not been possible to connect the efferent somas with the fibers.
(19) Interestingly, the M-cell soma which stains positive for AChE was ChAT negative.
(20) However, the distribution of the enzymes is indirectly correlated as high levels of particulate cyclic AMP-dependent protein kinase are present in the soma of neurons with high concentrations of adenylate cyclase in their terminals.