(a.) Single; not complex; not infolded or entangled; uncombined; not compounded; not blended with something else; not complicated; as, a simple substance; a simple idea; a simple sound; a simple machine; a simple problem; simple tasks.
(a.) Plain; unadorned; as, simple dress.
(a.) Mere; not other than; being only.
(a.) Not given to artifice, stratagem, or duplicity; undesigning; sincere; true.
(a.) Artless in manner; unaffected; unconstrained; natural; inartificial;; straightforward.
(a.) Direct; clear; intelligible; not abstruse or enigmatical; as, a simple statement; simple language.
(a.) Weak in intellect; not wise or sagacious; of but moderate understanding or attainments; hence, foolish; silly.
(a.) Not luxurious; without much variety; plain; as, a simple diet; a simple way of living.
(a.) Humble; lowly; undistinguished.
(a.) Without subdivisions; entire; as, a simple stem; a simple leaf.
(a.) Not capable of being decomposed into anything more simple or ultimate by any means at present known; elementary; thus, atoms are regarded as simple bodies. Cf. Ultimate, a.
(a.) Homogenous.
(a.) Consisting of a single individual or zooid; as, a simple ascidian; -- opposed to compound.
(a.) Something not mixed or compounded.
(a.) A medicinal plant; -- so called because each vegetable was supposed to possess its particular virtue, and therefore to constitute a simple remedy.
(a.) A drawloom.
(a.) A part of the apparatus for raising the heddles of a drawloom.
(a.) A feast which is not a double or a semidouble.
(v. i.) To gather simples, or medicinal plants.
Example Sentences:
(1) The accumulation of lipids and enzymes such as simple estarase, lipase, beta-HDH, alpha-GDH and NADPH-reductase in those areas, suggests that lipids are not a simple excretory product.
(2) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(3) A new and simple method of serotyping campylobacters has been developed which utilises co-agglutination to detect the presence of heat-stable antigens.
(4) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(5) Blatter requires a two-thirds majority of the 209 voters to triumph in the opening round, with a simple majority required if it goes to a second round.
(6) Each profile is described by a simple sequence of band transitions (BT-sequence).
(7) A simple method for ultrarapid freezing of cell cultures in monolayers was developed.
(8) A simple method of selective catheterization of the superficial femoral artery (SFA) following antegrade puncture of the common femoral artery is described.
(9) Although the relative contributions of different fuels varies greatly in different organisms, in none is there a simple reliance on stored ATP.
(10) Even if it were not the case that police use a variety of tricks to keep recorded crime figures low, this data would still represent an almost meaningless measure of the extent of crime in society, for the simple reason that a huge proportion of crimes (of almost all sorts) have always gone unreported.
(11) The method of sonicating L3 and Mf fragment antigens used in this study is simple, and its results are easy to observe.
(12) Simple cells that are nearly equally dominated by each eye always exhibit strong phase-specific interaction.
(13) More evil than Clocky , the alarm clock that rolls away when you reach out to silence it, or the Puzzle Alarm , which makes you complete a simple puzzle before it'll go quiet, the Money Shredding Alarm Clock methodically destroys your cash unless you rouse yourself.
(14) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(15) Treatment was monitored by simple measurements, and it's toxicity proved to be scanty.
(16) The presence of a previously unreported dipeptide transport mechanism within blood leukocytes and the selective enrichment of the granule enzyme, DPPI, within cytotoxic effector cells of lymphoid or myeloid lineage appear to afford a unique mechanism for the targeting of immunotherapeutic reagents composed of simple dipeptide esters or amides.
(17) The design of a simple dynamic knee simulator is described.
(18) Simple interconversion cannot account for the changes in binding that occur upon adding GMP-PNP or removing magnesium, since the increase in [R2]t exceeds the decrease in [R1]t. Moreover, the apparent amount of high-affinity complex exhibits a biphasic dependence on the concentration of [3H]histamine; an increase at low concentrations is offset by a decrease that occurs at higher concentrations.
(19) A rapid and simple method has been developed for the nondestructive distinction between aflatoxin B1 and the feed antioxidant, ethoxyquin.
(20) The stimuli were two simple tones in experiment 1 and two tonal complexes in both experiments 2 and 3.
Sipple
Definition:
(v. i.) To sip often.
Example Sentences:
(1) These factors are also associated with multiple endocrinological neoplasms type II of Sipple's syndrome.
(2) In a case of familial Sipple disease, follicular lining cells were replaced in areas with ACTH-containing cells.
(3) We recommend the calcium infusion test for: (a) screening for MCT in all Sipple relatives with normal or only slightly elevated basal S-CT, (b) postoperative control in both sporadic and hereditary MCT, (c) investigation of supposed non-MCT tumours with calcitonin production.
(4) Particular attention is drawn to two cases with bilateral sites (one male child, one woman with Sipple's syndrome) and the detection of possible local and distant malignancy.
(5) One hundred and fourteen cases of Sipple's syndrome have been reported in Japan.
(6) MCT would thus appear to be more frequently visualized by MIBG in cases of Sipple's syndrome than in sporadic cases.
(7) Sipple's syndrome (bilateral phaeochromocytoma and medullary thyroid carcinoma) is a multiple endocrinopathy with a familial occurrence.
(8) Approximately twice as often an isolated variant of the familial type of medullary carcinoma is involved, as compared with association with another endocrine affection, in particular pheochromocytoma (Sipple's syndrome), but associated forms will increase in number perspectively (multiple endocrine neoplasia 2A).
(9) Whether this is due to a real geographical variation of incidence, to a larger number of unreported cases in the Northern parts, or to presence of families with Sipple's syndrome in the South is unclear.
(10) Extensive studies revealed that the patient was suffering from a multiple endocrine neoplasia syndrome (type 2A or Sipple's syndrome) with bilateral pheochromocytomas and a medullary thyroid carcinoma.
(11) Of the multiple endocrine syndromes, the association between pheocromochytoma, medullary thyroid carcinoma (MTC) and parathyroid-hyperplasia (Sipple's syndrome, MEN IIa), and the association of MTC, with multiple monocutaneous neuromas and with a characteristic facial appearance (MEN IIb syndrome) are well known.
(12) In our opinion MR may replace both CT and nuclear scans in the work up of Sipple disease.
(13) Twenty-nine patients had the familial form of MTC; they were subclassified, on the basis of the phenotype, into a group of 15 patients with Sipple syndrome (or multiple endocrine neoplasia (MEN) Type 2A) and a group of 14 patients with mucosal-neuroma phenotype (or MEN type 2B).
(14) Although an exact reason for this remained unknown, our data could suggest that the adrenal tumors in Sipple's syndrome are primarily different from other types of pheochromocytoma, and thorough examinations for detecting the thyroid carcinoma should be necessary when the adrenal tumor is rich in epinephrine.
(15) This calcium infusion test was used in a prospective screening for medullary carcinoma of the thyroid (MCT) in 4 families with Sipple's syndrome as well as in 3 sporadic cases of MCT.
(16) Our patient had a strong family history for Sipple syndrome, which is considered to be transmitted as an autosomal dominant.
(17) However, such other symptoms of Sipple syndrome as presence of endocrine tumors are absent.
(18) This case report describes the localization and categorization of tumors using 99mTc(V)-dimercaptosuccinic acid and [131I]metaiodobenzylguanidine scans in a very uncommon case of medullary thyroid carcinoma associated with pheochromocytoma (Sipple's syndrome) and hepatocellular carcinoma.
(19) This study deals with 11 cases of thyroid medullary carcinoma of which 7 were familial cases including 3 cases of Sipple's syndrome and 4 cases of sporadic cases.
(20) A parallel between this situation and Sipple's disease in humans has previously been suggested.