(a.) Tainted with, or full of, sin; wicked; iniquitous; criminal; unholy; as, sinful men; sinful thoughts.
Example Sentences:
(1) Molsidomine and SIN-1 were tested in a thrombosis model in which thrombi are produced in small mesenteric vessels.
(2) These results support a hypothesis which proposes that ancestral SIN virus diverged into two distinct groups.
(3) Our studies show that SIN-1 and C87-3754 exert beneficial effects in a 6-h model of myocardial ischemia-reperfusion.
(4) Antibodies to all viruses were detected, and namely in these frequencies: SIN 0.9%, WN 16.9%, TAH 41.5%, CVO 23.1% and TBE 8.5%.
(5) As the later Spark might have said, a mortal sin against the commandment to love beauty wherever one may find it.
(6) The direct acting stimulants of soluble guanylate cyclase, sodium nitroprusside and SIN-1 (3-morpholino-sydnonimine), also increased the cGMP content of endothelial cells by 9.4 and 7.2 times, respectively.
(7) In superfused precontracted strips of rabbit aorta, methylene blue (MeB) or pyocyanin (Pyo, 1-hydroxy-5-methyl phenazinum betaine) at concentrations of 1-10 microM inhibited relaxations induced by endothelium-derived relaxing factor (EDRF), glyceryl trinitrate (GTN), S-nitroso-N-acetyl-penicillamine (SNAP) or 3-morpholino-sydnonimine (SIN-1).
(8) The likes of almond, blackberry and crocus first made way for analogue, block graph and celebrity in the Oxford Junior Dictionary in 2007, with protests at the time around the loss of a host of religious words such as bishop, saint and sin.
(9) These prostanoids were measured in platelets and endothelial cells alone or during their interaction, in the absence or presence of SIN-1.
(10) The haemodynamic effects of N-carboxy-3-morpholino-sydronimine-ethylester (molsidomine, SIN 10, Corvaton) were studied in anaesthetized mongrel dogs.
(11) The results indicated that both Sin B and Sal have inductive actions on drug metabolizing-phase I and phase II enzymes in mice and rats.
(12) Ten women with SIN were bilaterally salpingectomized.
(13) Analysis of the relationship between the pharmacodynamics and pharmacokinetics of SIN-1 suggests that an active metabolites is involved.
(14) The guanidine 3', 5'-cyclic monophosphate (cGMP) content (an index of EDRF production) was determined by radioimmunoassay under basal conditions and after acetylcholine (10(-5) M), bradykinin (10(-5) M) and SIN-1 (10(-4) M) stimulation.
(15) sin- mutants (defining six genes) were identified because they express HO in the absence of particular SWI products.
(16) We studied the effects of intracoronary injections of SIN-1 (0.8 mg), the active metabolite of molsidomine, on coronary artery diameters and coronary stenoses.
(17) Sessions included "naming the sin, lifting the shame" and "normal sinfulness or a sickness".
(18) The nitric oxide donor compound, 3-morpholinosydnonimine (SIN-1), was equipotent at relaxing the central and peripheral airways.
(19) Oxyhaemoglobin used for the assay of NO, inhibited the relaxation by SIN-1, but did not reduce vessel relaxations induced by GTN or iloprost, a stable prostacyclin analogue.
(20) A degraded SIN-1 solution that did not release NO was unable to block NMDA receptors.
Wicked
Definition:
(a.) Having a wick; -- used chiefly in composition; as, a two-wicked lamp.
(a.) Evil in principle or practice; deviating from morality; contrary to the moral or divine law; addicted to vice or sin; sinful; immoral; profligate; -- said of persons and things; as, a wicked king; a wicked woman; a wicked deed; wicked designs.
(a.) Ludicrously or sportively mischievous; disposed to mischief; roguish.
Example Sentences:
(1) "I had a not altogether satisfactory talk with Mark this morning" begins a typical confidential memo from Nigel Wicks, Mrs Thatcher's principal private secretary, to the British ambassador in Washington.
(2) It’s a wicked thing to do.” Thomson said the federal government had not notified him about approaching boats since 2009.
(3) It blamed "confrontation maniacs" for "[making their] servants of conservative media let loose a whole string of sophism intended to hatch all sorts of dastardly wicked plots and float misinformation".
(4) Fluid pressure changes and digital load measurements were simultaneously detected and recorded by use of, respectively, modified wick-in-needle and force plate transducers coupled to a microcomputer.
(5) In cats, brain tissue pressure (BTP) was measured by the wick-catheter method.
(6) The lack of knowledge about proper feeding and the use of bottles, fingers, and cotton wicks, which contribute to infection, diarrhea, and malnutrition, indicates a need for better health education.
(7) The light stimuli are provided by a Ganzfeld stimulator and the potentials are recorded with a disposable corneal wick electrode.
(8) IFP was measured in squamous cell carcinomas of the head and neck region in humans using the wick-in-needle technique.
(9) Our results on Ap4A are in contrast with those reported previously (C. Weinmann-Dorsch, G. Pierron, R. Wick, H. Sauer, and F. Grummt, Exp.
(10) Resembling a billhook, with Foule Crag its wickedly curved tip, this final flourish looks daunting but can be skirted to one side, up awkward slabs.
(11) titration with wicks pre-loaded with serial dilutions of rat plasma implanted post mortem for 15-20 min.
(12) Dance, perform, party in Hackney Wick One of my favourite venues in London is The Yard Theatre.
(13) Less conventional still is Muff Cafe, a custom-motorbike-workshop-cum-really-rather-good-organic-restaurant in Hackney Wick that a friend recommends on condition that "you don't fill it with Guardian readers".
(14) The wick catheter technique was developed in 1968 for measurement of subcutaneous pressure and has been modified for easy intramuscular insertion and continuous recording of interstitial fluid pressure in animals and humans.
(15) The corneal wick electrode is employed for bright flash electroretinogram (ERG) recordings and for research measurements of the early receptor potential.
(16) In the longer term, there is a risk that local government will be seen as being wicked or incompetent as it struggles to meet George Osborne's new spending figures.
(17) His next book was The Great Crash 1929 (1955), a wickedly entertaining account of what happened on Wall Street in that year.
(18) The mistake in most international crises is to over-personalise the issue by making a pariah of the wicked man and his corrupt family at the top and thinking that, once they go, all problems will easily be solved.
(19) Come the bell, the upstart nervelessly played it cool, almost a laughingly gay matador, his speed of hand and foot totally nullifying Liston’s wicked jab, the key to his armoury.
(20) Tissue pressures were recorded using saline-filled cotton-wool wicks.