(1) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(2) Renal micropuncture and microdissection techniques with ultramicro fluid analysis have been applied to evaluate single nephron function in the skate, Raja erinacea.
(3) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(4) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(5) The coefficient of variation in the integrated area of a single peak is 16%.
(6) The diffusion of Myocamicin in the prostatic tissue of patients undergoing prostatectomy after a single oral dose of 600 mg has been studied.
(7) Infection with opportunistic organisms, either singly or in combination, is known to occur in immunocompromised patients.
(8) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(9) Pituitary weight, mitotic index and chromosomes were studied in male rats following a single or repeated dose of estradiol-benzoate for a total period of 210 days.
(10) The manufacturers, British Aerospace describe it as a "single-seat, radar equipped, lightweight, multi-role combat aircraft, providing comprehensive air defence and ground attack capability".
(11) Cop rats, however, possess a single 'suppressor' gene which confers complete resistance to mammary cancer.
(12) Comparison if single injections of MSB and atropine in normal subjects also demonstrated a more reliable dose-response relationship with MSB.
(13) Since interferon alfa-2b (Intron A) is useful as a single agent, it is important to determine if interferon can be combined with standard chemotherapy to improve both response and survival in patients with cancer.
(14) This suggests that Mg2+ accelerated both reactions from a single class of site.
(15) In crosses between inverted repeats, a single intrachromatid reciprocal exchange leads to inversion of the sequence between the crossover sites and recovery of both genes involved in the event.
(16) Median effect analysis was applied for the evaluation of in vitro effect by the growth inhibition, and the in vivo effect by comparison of the increase of life span (ILS) in a combined group with the sum of ILS's in 2 single agent groups.
(17) Certainly, Saunders did not land a single blow that threatened to stop his opponent, although he took quite a few himself that threatened his titles in the final few rounds.
(18) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(19) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.
(20) Such an approach to investigations into subclinical mastitis is not feasible by means of either single- or double-parameter techniques.
Singlet
Definition:
(n.) An unlined or undyed waistcoat; a single garment; -- opposed to doublet.
Example Sentences:
(1) Quantitative singlet-singlet energy-transfer measurements were carried out to determine changes in the distance between the two Met-84 H4 sites within the same nucleosome following conformational transitions which we have reported earlier.
(2) In neutral or basic aqueous solution guanine, guanosine, deoxyguanosine, guanylic acid, deoxyguanylic acid, thymine, and uracil reacted with singlet oxygen.
(3) This broad singlet does not appear to be a tyrosyl radical.
(4) The ESR spectrum exhibited a singlet (g = 2.0021) with a 5.4-G peak-to-peak linewidth.
(5) While hydroxyl radicals produce DNA strand breaks and sites of base loss (AP sites) in high yield and react with all four bases of DNA, singlet oxygen generates predominantly modified guanine residues and few strand breaks and AP sites.
(6) These changes are detected by variations in the rate of decay of the excited singlet state of pyrene after pulsation with a 10-nsec ruby laser flash.
(7) This has been demonstrated using a separated-surface-sensitizer system for generating chemically pure singlet oxygen, eliminating most of the complications that arise with singlet oxygen generation by conventional photosensitization.
(8) Since all the sulfhydryl groups of beta-crystallin are known to be exposed on the surface of the protein (Andley et al, 1982, Biochemistry 21, 1853), these results suggest that the pronounced changes in conformation of beta-crystallin by singlet oxygen may be due to a rapid loss of the protein tertiary structure by oxidation of the sulfhydryl groups.
(9) The quantum yields for singlet oxygen formation via energy transfer from triplet alpha-terthienyl have been obtained from time-resolved measurements of its IR phosphorescence: these yields are in the 0.6-0.8 range in non-polar and polar (hydroxylic and non-hydroxylic) solvents.
(10) Attempts with various chemical sources of singlet oxygen to determine whether this species inactivates DNA did not give an unequivocal answer.
(11) The near IR emission at 1270 nm following pulsed laser excitation of methylene blue in deuterium oxide, was used to study the interaction of a singlet molecular oxygen (1O2) with (i) 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its oxidation products, and (ii) biosubstrates of relevance in Parkinson's disease.
(12) This differs from results obtained with native enzyme, where pterin acts as a sensitizer via efficient singlet-singlet energy transfer to FADH2.
(13) Chemiluminescence appears to result from a side reaction involving singlet oxygen attack on the alpha-methene bridge, yielding a dioxetane.
(14) In acetonitrile, diphenylamine was oxidized by singlet oxygen to form N-phenyl-p-benzoquinonimine.
(15) This information combined with the fluorescence quantum yield data account for the low values for singlet oxygen production.
(16) Other roles of carnosine, such as chelation of metal ions, quenching of singlet oxygen, and binding of hydroperoxides, are also discussed.
(17) Tests for the ability of singlet oxygen to induce lambda prophage in E. coli K12 also proved negative.
(18) The light-dependent reaction appears to be mediated by singlet oxygen.
(19) Superoxide anion (O-2) and singlet oxygen (1O2) were estimated but undetectable during the dopa-tyrosinase reaction.
(20) Evidence is presented for three mechanisms of inhibition by extendible nucleotides (of dhp and ara types) exhibiting frequent internalization: araATP acted as a simple pseudoterminator of alpha and beta polymerases, but was easily extended past singlet sites by Herpesviridae polymerases and only stalled at sites requiring two or more araATP insertions in a row.