(1) Skene and Virag recently found that the cysteines in the N-terminus are fatty-acylated and that this post-translational modification correlates with membrane-binding ability.
(2) The diagnosis of a rare Skene's duct cyst in a newborn was made based on its location in relation to the urethra and the demonstration of transitional epithelium in the cyst wall.
(3) We report a case of calculi in a Skene's gland abscess produced by Ureaplasma urealyticum.
(4) Among the hypotheses to account for this failure is the proposition that certain axonal proteins necessary for axon growth are expressed in much greater abundance in developing than in mature neurons, and that these proteins are not reinduced after injury to mature axons (Skene and Willard, 1981b).
(5) A biphasic curve was also noted in one woman with a Skene duct cyst and in the one who had genuine stress incontinence only.
(6) The largest increase, to nearly 200 X normal with 6 hr labeling, was seen in a protein with a molecular weight of 45 kDa and a pl of about 4.5, resembling a protein that has previously been designated a "growth-associated protein" (GAP-43; Skene and Willard, 1981a).
(7) Nine of 12 patients had urethral diverticula, two had Skene duct cysts, and one had genuine stress incontinence.
(8) A provisional diagnosis of carcinoma of skene's duct or vaginal leiomyoma was entertained and an excisional biopsy performed.
(9) The cyst was thought to have derived from left Skene's duct and marsupialized.
(10) Previous studies have shown that increased amounts of pulse-labeled GAP-43 undergo fast axonal transport in regenerating neurons (Benowitz et al., 1981; Skene and Willard, 1981 a, b).
(11) The Skene's duct cyst, which presents as a cystic mass just around the urethral meatus, is a rare congenital abnormality in the female newborn.
(12) Therapy involves the submucosal injection of triamcinolone acetonide around Skene's glands to decrease inflammation and scarring.
(13) The histologic and immunohistological differences between adult prostate as seen in our cases and female paraurethral (Skene's) glands are discussed.
(14) Before axonal outgrowth, the growth-associated protein GAP-43 is distributed equally among the growth cones of the minor processes; it is preferentially concentrated in the axonal growth cone once polarity has been established (Goslin, K., D. Schreyer, J. Skene, and G. Banker.
(15) The morphological and embryological significance of the Skene's duct and related cysts are discussed.
(16) We describe such a lesion that arose secondary to an abscess of Skene's glands in a 14-year-old sexually active adolescent.
(17) Hopefully we’re moving to a place where it’s no big deal to be gay, on the sporting field or in any other part of life.” The courageous journey of Ian Roberts, rugby league's first openly gay player | Patrick Skene Read more One of the most respected names in international netball, former Australian captain turned commentator Liz Ellis, says Brazill’s unquestioned acceptance makes her proud of her sport.
(18) Development or regeneration of axons in several systems is accompanied by 20-100-fold increases in the synthesis of an acidic, axonally transported membrane protein with an apparent molecular weight of 43-50,000 (Benowitz and Lewis, 1983; Skene and Willard, 1981a, b), which we designate GAP-43.
(19) Following a search of available literature we have been able to find Skene's duct cyst reported in only 10 newborns.
(20) This case and previously published laboratory data suggest that intravaginal nonoxynol-9 deserves further study as a treatment for resistant trichomoniasis, though trichomonal coinfection of the patient's urethra, Skene glands, and sexual partner would not likely be resolved by such therapy.