What's the difference between skin and xanthoma?

Skin


Definition:

  • (n.) The external membranous integument of an animal.
  • (n.) The hide of an animal, separated from the body, whether green, dry, or tanned; especially, that of a small animal, as a calf, sheep, or goat.
  • (n.) A vessel made of skin, used for holding liquids. See Bottle, 1.
  • (n.) The bark or husk of a plant or fruit; the exterior coat of fruits and plants.
  • (n.) That part of a sail, when furled, which remains on the outside and covers the whole.
  • (n.) The covering, as of planking or iron plates, outside the framing, forming the sides and bottom of a vessel; the shell; also, a lining inside the framing.
  • (v. t.) To strip off the skin or hide of; to flay; to peel; as, to skin an animal.
  • (v. t.) To cover with skin, or as with skin; hence, to cover superficially.
  • (v. t.) To strip of money or property; to cheat.
  • (v. i.) To become covered with skin; as, a wound skins over.
  • (v. i.) To produce, in recitation, examination, etc., the work of another for one's own, or to use in such exercise cribs, memeoranda, etc., which are prohibited.

Example Sentences:

  • (1) The catheter must be meticulously fixed to the skin to avoid its movement.
  • (2) Elements in the skin therefore seemed to enhance nerve regeneration and function.
  • (3) This is a fascinating possibility for solving the skin shortage problem especially in burn cases.
  • (4) Blood flow decreased immediately after skin expansion in areas over the tissue expander on days 0 and 1 and returned to baseline levels within 24 hours.
  • (5) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
  • (6) Currently, photodynamic therapy is under FDA-approved clinical investigational trials in the treatment of tumors of the skin, bronchus, esophagus, bladder, head and neck, and of gynecologic and ocular tumors.
  • (7) Immunofluorescent staining for HLA-DR showed dermal positivity in 12 of 13 involved- and 9 of 13 uninvolved-skin biopsy specimens from scleroderma patients, compared with only 1 of 10 controls.
  • (8) Blood flow was measured in leg and torso skin of conscious or anesthetized sheep by using 15-micron radioactive microspheres (Qm) and the 133Xe washout method (QXe).
  • (9) A similar interference colour appeared after incubating sections of rat skin with chymase.
  • (10) Peptides from this region bind to actin, act as mixed inhibitors of the actin-stimulated S1 Mg2(+)-ATPase, and influence the contractile force developed in skinned fibres, whereas peptides flanking this sequence are without effect in our test systems.
  • (11) This study was designed to examine the effect of the storage configuration of skin and the ratio of tissue-to-storage medium on the viability of skin stored under refrigeration.
  • (12) Somatostatin-like immunoreactivity has been found to occur in nerve terminals and fibres of the normal human skin using immunohistochemistry.
  • (13) We recommend analysing the urine for porphyrins in HIV-positive patients who have chronic photosensitivity of the skin.
  • (14) We investigated the incidence of skin cancer among patients who received high doses of PUVA to see whether such incidence increased.
  • (15) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
  • (16) In order to develop a sampling strategy and a method for analyzing the circadian body temperature pattern, we monitored estimates of the temperature in four ways using rectal, oral, axillary and deep body temperature from the skin surface every hour for 72 consecutive hours in 10 normal control subjects.
  • (17) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
  • (18) Compliance during dehydration was 7.6 and 12.5% change in IFV per millimeter Hg fall in IFP (micropipettes) in skin and muscle, respectively, whereas compliance in subcutis based on perforated capsule pressure was 2.0% change in IFV per millimeter Hg.
  • (19) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
  • (20) 14 patients with painful neuroma, skin hyperesthesia or neuralgic rest pain were followed up (mean 20 months) after excision of skin and scar, neurolysis and coverage with pedicled or free flaps.

Xanthoma


Definition:

  • (n.) A skin disease marked by the development or irregular yellowish patches upon the skin, especially upon the eyelids; -- called also xanthelasma.

Example Sentences:

  • (1) The reason(s) for the xanthoma formation and premature atherosclerosis are not clearly understood.
  • (2) The three xanthomas from two FH homozygotes exhibited marked lipid accumulation in histiocytic foam cells but no lipid deposits in the endothelium of blood vessels in the lesions.
  • (3) This rare lesion, previously reported to occur only in the oral cavity, is characterized by a verrucous epithelial proliferation accompanied by xanthoma cells distributed exclusively in the papillary dermis.
  • (4) A skin biopsy demonstrated infiltration of xanthoma cells and foamy cells in the dermis.
  • (5) The clinical consequences of familial hypercholesterolemia (FH) result from its metabolic peculiarities that persist from very early childhood, leading to the accumulation of cholesterol in the form of xanthomas in skin and tendons and atheromatous lesions in the arterial wall, in particular, in the aorta and the stem of coronary arteries.
  • (6) Perhaps in some way plant sterols initiated the development of xanthomas with otherwise normal plasma cholesterol levels.
  • (7) In the remaining family, the proband and his sibling, both having relatively severe hypercholesterolemia and Achilles tendon xanthomas, shared an RFLP haplotype, although the proband's other sibling with moderate hypercholesterolemia but without Achilles tendon xanthomas did not.
  • (8) Xanthelasma palpebrarum is the most common xanthoma and is associated with other xanthomas or hyperlipemia syndromes in only 5 percent of the patients--even though one third of the affected patients have an elevated serum cholesterol level.
  • (9) A 47-year-old male patient with tuberous xanthomas, xanthochromia striata palmaris, hypercholesterolemia, hypertriglyceridemia, chylomicronemia and a "broad-beta" band on agarose gel electrophoresis is the subject of this report.
  • (10) To explore whether the reported xanthoma-reducing effects of probucol are related to tissue-specific mechanisms of the drug, the influence of probucol on cholesterol efflux from cultured human skin fibroblasts was investigated.
  • (11) Survivors at ages of 19 months to 16.5 years had considerable morbidity with pruritus occurring in 70%, jaundice in 48%, xanthomas in 30%, 74% having hepatomegaly and 63% splenomegaly.
  • (12) The histologic diagnosis was sclerosing (ossifying) xanthoma.
  • (13) Intracranial fibrous xanthoma is extremely rare; only 11 cases have been reported so far.
  • (14) On the other hand, severe talagia was rarely found in rheumatoid arthritis, and no case was related to the presence of tophi or xanthomas of the Achilles tendon.
  • (15) Large Achilles tendon xanthomas of the type found in severe familial hypercholesterolemia were the first manifestation of cholestanolosis (cerebrotendinous xanthomatosis) in our patient, an otherwise asymptomatic normolipidemic 21-year-old woman.
  • (16) They differed, however, from the typical presentation in lacking the Achilles tendon xanthomas characteristic of this condition.
  • (17) Cerebrotendinous xanthomatosis is a rare hereditary disease, which manifests with tendinous xanthomas, cataracts, dementia and nervous system involvement.
  • (18) Xanthoma was produced in diet-induced hypercholesterolemic rabbits by intradermal dextran sulfate injections.
  • (19) These findings support previous biopsy data indicating active uptake of LDL by macrophages within xanthoma and suggest that 99mTc-LDL imaging of xanthomas may be useful in studies of the effects of diet and drugs on the accumulation of lipoproteins by atherosclerotic plaques.
  • (20) And there was a collection of xanthoma-like foamy cells and invasive inflammatory cells.

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