What's the difference between skin and xeroderma?

Skin


Definition:

  • (n.) The external membranous integument of an animal.
  • (n.) The hide of an animal, separated from the body, whether green, dry, or tanned; especially, that of a small animal, as a calf, sheep, or goat.
  • (n.) A vessel made of skin, used for holding liquids. See Bottle, 1.
  • (n.) The bark or husk of a plant or fruit; the exterior coat of fruits and plants.
  • (n.) That part of a sail, when furled, which remains on the outside and covers the whole.
  • (n.) The covering, as of planking or iron plates, outside the framing, forming the sides and bottom of a vessel; the shell; also, a lining inside the framing.
  • (v. t.) To strip off the skin or hide of; to flay; to peel; as, to skin an animal.
  • (v. t.) To cover with skin, or as with skin; hence, to cover superficially.
  • (v. t.) To strip of money or property; to cheat.
  • (v. i.) To become covered with skin; as, a wound skins over.
  • (v. i.) To produce, in recitation, examination, etc., the work of another for one's own, or to use in such exercise cribs, memeoranda, etc., which are prohibited.

Example Sentences:

  • (1) The catheter must be meticulously fixed to the skin to avoid its movement.
  • (2) Elements in the skin therefore seemed to enhance nerve regeneration and function.
  • (3) This is a fascinating possibility for solving the skin shortage problem especially in burn cases.
  • (4) Blood flow decreased immediately after skin expansion in areas over the tissue expander on days 0 and 1 and returned to baseline levels within 24 hours.
  • (5) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
  • (6) Currently, photodynamic therapy is under FDA-approved clinical investigational trials in the treatment of tumors of the skin, bronchus, esophagus, bladder, head and neck, and of gynecologic and ocular tumors.
  • (7) Immunofluorescent staining for HLA-DR showed dermal positivity in 12 of 13 involved- and 9 of 13 uninvolved-skin biopsy specimens from scleroderma patients, compared with only 1 of 10 controls.
  • (8) Blood flow was measured in leg and torso skin of conscious or anesthetized sheep by using 15-micron radioactive microspheres (Qm) and the 133Xe washout method (QXe).
  • (9) A similar interference colour appeared after incubating sections of rat skin with chymase.
  • (10) Peptides from this region bind to actin, act as mixed inhibitors of the actin-stimulated S1 Mg2(+)-ATPase, and influence the contractile force developed in skinned fibres, whereas peptides flanking this sequence are without effect in our test systems.
  • (11) This study was designed to examine the effect of the storage configuration of skin and the ratio of tissue-to-storage medium on the viability of skin stored under refrigeration.
  • (12) Somatostatin-like immunoreactivity has been found to occur in nerve terminals and fibres of the normal human skin using immunohistochemistry.
  • (13) We recommend analysing the urine for porphyrins in HIV-positive patients who have chronic photosensitivity of the skin.
  • (14) We investigated the incidence of skin cancer among patients who received high doses of PUVA to see whether such incidence increased.
  • (15) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
  • (16) In order to develop a sampling strategy and a method for analyzing the circadian body temperature pattern, we monitored estimates of the temperature in four ways using rectal, oral, axillary and deep body temperature from the skin surface every hour for 72 consecutive hours in 10 normal control subjects.
  • (17) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
  • (18) Compliance during dehydration was 7.6 and 12.5% change in IFV per millimeter Hg fall in IFP (micropipettes) in skin and muscle, respectively, whereas compliance in subcutis based on perforated capsule pressure was 2.0% change in IFV per millimeter Hg.
  • (19) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
  • (20) 14 patients with painful neuroma, skin hyperesthesia or neuralgic rest pain were followed up (mean 20 months) after excision of skin and scar, neurolysis and coverage with pedicled or free flaps.

Xeroderma


Definition:

  • (n.) Ichthyosis.
  • (n.) A skin disease characterized by the presence of numerous small pigmented spots resembling freckles, with which are subsequently mingled spots of atrophied skin.

Example Sentences:

  • (1) The SCE frequencies of xeroderma pigmentosum (XP12RO) and normal human lymphoblastoid cell lines were also found to be unaffected by Na2SeO3 concentrations that produced elevated SCE frequencies in whole blood cultures.
  • (2) Fetal autopsy case of xeroderma pigmentosum was reported.
  • (3) The cytogenetic study of a case of cutaneous squamous cell carcinoma developed in a child affected by xeroderma pigmentosum is described.
  • (4) Dysplastic naevus syndrome (DNS) is frequently observed in association with familial melanoma and xeroderma pigmentosum (XP), but the role of UV-light in the development of DNS has not been elucidated.
  • (5) The data indicate that the repair of lesions induced by these substances may have common rate-limiting steps, a conclusion previously indicated by the repair deficiency in xeroderma pigmentosum cells in which a single mutation eliminates the repair of damage caused by each of these agents.
  • (6) Skin phototesting and cellular sensitivity studies were performed in a patient with xeroderma pigmentosum (XP) complementation group E (XP80TO) at the ages of 50 and 55 years.
  • (7) Include is a discussion of xeroderma pigmentosum, ataxia-telangiectasia.
  • (8) This phenomenon is also displayed by xeroderma pigmentosum cells (complementation groups A and F), which are deficient in the excision repair of UV-induced pyrimidine dimers in the DNA.
  • (9) This syndrome is related to xeroderma pigmentosum complementation group D but differs from it in the absence of skin tumors, at least in the first two decades of life.
  • (10) Diploid xeroderma pigmentosum (XP) skin fibroblast strains from various XP-complementation groups (B, C, G, and H) were transformed with an origin-defective SV40 early region or with the pSV3 gpt plasmid.
  • (11) We studied the UV-sensitivity of cultured fibroblast cells derived from these PMD cases, as compared with UV-sensitive Cockayne syndrome (CS) and xeroderma pigmentosum (XP) cells as positive controls.
  • (12) A genetic model for some cases of excision-deficient xeroderma pigmentosum (XP) is proposed in which the trait (i.e., XP) is expressed if and only if the individual is homozygous or hemizygous for defective alleles at more than one of a specific set of loci.
  • (13) Patients suffering from the genetic disorder xeroderma pigmentosum (XP) display an extreme sensitivity of their skin to sun (UV) exposure and predisposition to skin cancer due to deficiencies in the excision DNA repair pathway.
  • (14) The xeroderma cells were competent in their ability to excise 3-methyl adenine adducts.
  • (15) An apparent linear dose response within the dose range used was observed for UV-induced mutations in both normal and xeroderma pigmentosum fibroblasts.
  • (16) A 43-year-old man with xeroderma pigmentosum, XP97TO, was allocated to complementation group D. He had had moderate photosensitivity at age 1 year and freckles by age 6 but no neurologic abnormalities.
  • (17) Extracts from xeroderma pigmentosum (XP) cells are defective in repair synthesis.
  • (18) No discernible difference could be detected between the fluence-response curves of pyrimidine dimers for untreated and MMC-treated repair-deficient xeroderma pigmentosum cells of group A.
  • (19) inactivation of transient expression of the bacterial gpt gene contained in a non-replicating expression vector plasmid, pSV2catSVgpt, was much greater in three xeroderma pigmentosum lines than in the four other human cell lines tested.
  • (20) This activity is absent in xeroderma pigmentosum group A cells.

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