(n.) A place of deep mud or mire; a hole full of mire.
(n.) A wet place; a swale; a side channel or inlet from a river.
() imp. of Slee, to slay. Slew.
(n.) The skin, commonly the cast-off skin, of a serpent or of some similar animal.
(n.) The dead mass separating from a foul sore; the dead part which separates from the living tissue in mortification.
(v. i.) To form a slough; to separate in the form of dead matter from the living tissues; -- often used with off, or away; as, a sloughing ulcer; the dead tissues slough off slowly.
(v. t.) To cast off; to discard as refuse.
Example Sentences:
(1) Mucosal sloughing with hemorrhage and infarction were observed at 3 hours.
(2) More suppliers have told the Guardian of extensive negotiations with Amazon staff in Slough, adding to the impression that the company carries out important trading activities in the UK and so could be liable for tax.
(3) In mammalian small intestine absorptive cells are known to migrate from the villus base to the villus tip from which they slough.
(4) The most marked effect of the ZnSO4 took the form of necrosis and sloughing of surface cells in both strains one-half day after ZnSO4 irrigation.
(5) Cameron’s call for the Malaysian political class to fight corruption came as he pitched the country’s financiers the chance to invest in £17bn worth of UK infrastructure projects ranging from a Leeds orbital road route, Slough town centre and prime residential properties along the Thames.
(6) The histopathologic features include peritubular sclerosis, small vessel sclerosis, premature germ cell sloughing, and variable degrees of hypospermatogenesis.
(7) Changes in sperm head morphology are caused by (1) a dramatic reshaping and consolidation of the acrosome in which excess plasma membrane overlying it is sloughed as a cluster of vesicles, (2) a reorientation of the nucleus almost parallel to the axis of the tail and (3) distal movement of the droplet from its initial envelopment of the nucleus to an eccentric position on the anterior segment of the midpiece.
(8) Acute hypothermia induced a sloughing of cells from the villi into the lumen of the gut, as indicated by an increased DNA in luminal washings.
(9) Toxic epidermal necrolysis results in skin sloughing that resembles a partial-thickness thermal injury.
(10) Scanning electron microscopy revealed that in diabetic BB rats there was consistent evidence of swollen cells, raised nuclei, and sloughing of nuclei in endothelial cells of the aorta.
(11) However, after sloughing of labelled cells in the intestinal lumen, Pu was reabsorbed by the distal epithelial cells.
(12) It places the implant deep to prevent skin slough and irregularities in skin surface contour.
(13) Newer communities have settled in towns and cities such as Milton Keynes, Slough, Northampton, Southampton, and in London, notably Ealing, Tower Hamlets and Newham.
(14) Sloughing vesiculobullous oral lesions are a frequent component.
(15) Within 1 day of injury, columnar epithelium sloughed intact from the trachea with a concomitant reduction of nearly 35% in the basal cell population.
(16) Early changes (0-2 hours) included focal tumor and endothelial cell vacuolation and swelling as well as sloughing of tumor cells into papillary spaces.
(17) Histologically, the 4.0 ppm animals demonstrated bronchiolar epithelial necrosis and sloughing, bronchiolar edema with macrophages, and focal pulmonary edema.
(18) Ciliated cells had a slightly vesiculated cytoplasm, and many were in the process of being sloughed from the epithelial surface.
(19) Preliminary histochemical studies show that terminin is also found in the superficial epithelial layer of the esophagus, where terminal differentiation is followed by apoptosis and sloughing off into the lumen.
(20) In both the mouse and the rat, some of the superficial cells sloughed between fetal day 18 or 19 and the day of birth.
Ulcer
Definition:
(n.) A solution of continuity in any of the soft parts of the body, discharging purulent matter, found on a surface, especially one of the natural surfaces of the body, and originating generally in a constitutional disorder; a sore discharging pus. It is distinguished from an abscess, which has its beginning, at least, in the depth of the tissues.
(n.) Fig.: Anything that festers and corrupts like an open sore; a vice in character.
(v. t.) To ulcerate.
Example Sentences:
(1) Calcium alginate dressings have been used in the treatment of pressure ulcers and leg ulcers.
(2) We evaluated the circadian pattern of gastric acidity by prolonged intraluminal pHmetry in 15 "responder" and 10 "nonresponder" duodenal ulcer patients after nocturnal administration of placebo, ranitidine, and famotidine.
(3) Exudative inflammatory processes predominate in the ulcer floor.
(4) In the past 6 years 26 patients underwent operation for recurrent duodenal ulcer after what was considered to be an "adequate" initial operation.
(5) Systemic corticosteroids (i.e., prednisone, prednisolone or methylprednisolone) have improved the survival rate of patients with moderate and severe ulcerative colitis.
(6) A leg ulcer in a 52-year-old renal transplant patient yielded foamy histiocytes containing acid-fast bacilli subsequently identified as a Runyon group III Mycobacterium.
(7) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(8) Serum pepsinogen 1, serum gastrin, ABO blood groups, secretor status of ABH blood group substances and behavioral factors were studied in 15 patients with duodenal ulcer and 61 their relatives affected and unaffected to duodenal ulcer.
(9) Local injections of contrykal into the ulcer had inhibited proteinase activity and had a positive therapeutic effect.
(10) For that reason we determine basal serum pepsinogen I (PG I) levels in 25 ulcerous patients and 75% of their offspring and to a control group matched by age and sex.
(11) Useful studies on the relationship between these acute lesions and peptic ulceration are rare.
(12) A neodymium YAG (Nd:YAG) laser was evaluated in a dog ulcer model used in the same manner as is recommended for bleeding patients (power 55 W, divergence angle 4 degrees, with CO2 gas-jet assistance).
(13) The ulcers on seven of ten legs (70%) treated with Unna's boots and on 10 of 14 legs (71%) treated with elastic support stocking healed.
(14) In the controlled wound care group, only three ulcers in three patients achieved complete healing; the remaining 24 ulcers in 20 patients failed to achieve even 50% healing in the stipulated 3-month period.
(15) To investigate the possibility that an abnormality of gastric emptying exists in duodenal ulcer and to determine if such an abnormality persists after ulcer healing, scintigraphic gastric emptying measurements were undertaken in 16 duodenal ulcer patients before, during, and after therapy with cimetidine; in 12 patients with pernicious anemia, and in 12 control subjects.
(16) The pathomechanism, how C. pylori facilitates the development of peptic ulcer is since hypothetical.
(17) Three types of responses were observed: group A, no inhibition of gastric acid secretion occurred in 17 (40%) ulcer patients and in three (18%) controls (p less than 0.05); group B, inhibition of gastric acidity occurred in seven (16%) ulcer patients and in 12 (71%) controls (p less than 0.05), and group C, retarded gastric acid inhibition occurred in 19 (44%) duodenal ulcer patients and in 2 (12%) controls (p less than 0.05).
(18) Nine patients with duodenal ulcer were studied before and 2--3 months after proximal gastric vagotomy (PGV).
(19) In group III, multiple confluent ulcers were produced in the cheek pouch on one side, with a single ulcer in the contralateral cheek pouch; no drug was applied, and the tissues were prepared for histology.
(20) Gastric metaplasia was present in only 8% of 48 bulbar ulcer cases.