(n.) A contagious, constitutional, febrile disease characterized by a peculiar eruption; variola. The cutaneous eruption is at first a collection of papules which become vesicles (first flat, subsequently umbilicated) and then pustules, and finally thick crusts which slough after a certain time, often leaving a pit, or scar.
Example Sentences:
(1) A direct fluorescent-antibody test for smallpox is described which utilizes a conjugated antivaccinia serum that was purified by diethylaminoethyl fractionation.
(2) A notable example is percutaneous smallpox vaccination together with the intradermal injection of BCG.
(3) A young girl, vaccinated against smallpox 6 years before suffered from a persistent vaccinia virus infection and a congenital skin disease, i.e.
(4) This would prove the early reactions to be allergic responses of organisms sensitized against smallpox vaccine, capable of stimulating antibody formation.
(5) On the basis of the data obtained PHAT could be recommended as a test for the assessment of the immunological efficacy of the smallpox vaccinations.
(6) Vaccinia-specific antibodies were found in 4 human sera collected 6 weeks after smallpox vaccination.The serological results provide the first laboratory evidence of a monkeypox reservoir in wild monkeys.
(7) The last case of virulent smallpox occurred in Bangladesh in October 1975, and of mild smallpox in Ethiopia in August 1976.
(8) Since May 1980 when the 33rd World Health Assembly declared the global eradication of smallpox, WHO has been developing a comprehensive system of surveillance aimed at maintaining the world permanently free from this disease.
(9) Smallpox victims were estimated at 10-15 million each year, of whom 1.5-2.0 million died.
(10) Five instances of side-effects after oral smallpox immunisation (out of 2568 persons orally immunised) are reported.
(11) In 1796, Edward Jenner developed the first effective vaccine against an infectious disease by using cowpox virus to prevent subsequent infection with smallpox.
(12) Subcutaneous sensitization of guinea pigs with -vaccine, and also an intracardiac injection of smallpox or measles vaccine induced production of brain autoantibodies, whereas subcutaneous or intradermal immunization of the animals with liver viral vaccines was not accompanied by the formation of autoantibodies and development of the pathological processes in the nervous system tissue.
(13) If this is verified, we may say farewell to routine smallpox vaccination.
(14) Useful lessons may be drawn from the successful global Smallpox Eradication Program and applied to the current campaign in the areas of surveillance, strategy, operations, and evaluation.
(15) With this immunization schedule it was possible to obtain smallpox antisera containing precipitins (in a titer of 1:32), hemagglutinins (1:1280), and antibody detectable by the indirect immunofluorescence technique (1:2560).
(16) In sequential serum specimens, the radioimmunoassay test indicated fourfold or greater increases in all of the smallpox patients and in six of eight vaccinated persons.
(17) The obstetric outcome (abortions, stillbirths, prematurity, mature births, and congenital abnormalities) in a group of 1522 consecutive pregnant patients who had smallpox vaccinations during recent pregnancies was compared to that in a similar control group of 2024 consecutive pregnant patients who did not receive any antenatal vaccination.
(18) In this pilot study clinical, electrocardiographic, chemical and immunological findings have been studied during a six weeks' follow-up after routine immunisation (mumps, polio, tetanus, smallpox, diphtheria and type A meningococcal disease) among 234 Finnish conscripts at the beginning of their military service.
(19) The history of smallpox is recounted through the eyes of those who bore witness to its terrors.
(20) All were tuberculin-tested and all had received primary smallpox vaccination but had not been vaccinated with BCG.
Syphilis
Definition:
(n.) The pox, or venereal disease; a chronic, specific, infectious disease, usually communicated by sexual intercourse or by hereditary transmission, and occurring in three stages known as primary, secondary, and tertiary syphilis. See under Primary, Secondary, and Tertiary.
Example Sentences:
(1) Sera of 375 blood donors which were seropositive for syphilis were examined for antibodies against Entamoeba histolytica.
(2) The dramatic nationwide increase of primary and secondary syphilis in women has precipitated a dramatic rise in congenital syphilis.
(3) These structures were also found in the blood or spinal fluid (SF) of asymptomatic patients with both positive and negative serological tests for syphilis.
(4) These findings provide a framework for future investigations of our congenital syphilis model.
(5) Several months later, as the patient experienced relapses with cerebellar and spinal cord involvement, falsely positive tests for syphilis were found and an antibiotic treatment was given.
(6) The expression of such secondary and tertiary syphilis is commonly masked and distorted by the long-term effects of subcurative doses of antibiotics; in fact, late latent and tertiary syphilis produce symptoms and immunosuppression similar to the profile of AIDS.
(7) The CSF-TPHA test was positive in four out of 12 children, and the CSF-VDRL test was negative in all the children with active congenital syphilis.
(8) Binding of aCL in syphilis to solid phase CL was competitively inhibited by either addition of the cofactor or fluid phase CL.
(9) Serological tests for hepatitis A (HA) and B (HB), syphilis and HIV were performed on blood samples from 3 groups of homosexual men: 220 and 124 asymptomatic men being investigated in 1978 and 1980 respectively and another 98 men suffering from HA during the winter 1979-80.
(10) To evaluate the effect of ceftriaxone in treating latent syphilis or asymptomatic neurosyphilis in patients infected with the human immunodeficiency virus (HIV).
(11) Lyme borreliosis has in common features with another spirochetosis, syphilis, e.g.
(12) Compared to cases in the previous year, infectious syphilis cases among prostitutes and seasonal farm workers decreased 51.3 per cent and 26.8 per cent, respectively.
(13) A clinically manifest primary or secondary syphilis that develops during pregnancy has become an extremely rare occurrence.
(14) Beside being responsible for positivity of the VDRL test in the context of syphilis, APAB (false serological reactions for syphilis, LA, anticardiolipin antibodies) have also been detected in systemic lupus erythematosus (SLE) and lupus-like syndromes, after intake of certain drugs, and, more rarely, in a number of diseases (table I).
(15) A protocol outline for diagnosis and therapy of syphilis is included in the discussion.
(16) Cryptococcosis occurred in association with toxoplasmosis in one patient who developed syphilis in the follow-up; oligoclonal distribution of gamma globulins occurred in this case.
(17) However, the treatment failed to prevent infection in the infant, and the baby had developed signs of congenital syphilis at 10 weeks of age.
(18) The protocol was devised by first evaluating a range of kits in London using a battery of African and non-African sera and then field testing 1455 sera in Malaŵi, which included 184 sera from leprosy patients and 60 sera from syphilis patients to check for cross-reactivity.
(19) Individual sequelae are most significnat when congenital syphilis is allowed to develop due to delays in treating the pregnant woman or newborn child.
(20) There is a suggestion of a plateau having occurred in adult and congenital syphilis, possibly caused by saturation effect on the high-risk population.