(a.) Having the constituent parts so compact, or so firmly adhering, as to resist the impression or penetration of other bodies; having a fixed form; hard; firm; compact; -- opposed to fluid and liquid or to plastic, like clay, or to incompact, like sand.
(a.) Not hollow; full of matter; as, a solid globe or cone, as distinguished from a hollow one; not spongy; dense; hence, sometimes, heavy.
(a.) Having all the geometrical dimensions; cubic; as, a solid foot contains 1,728 solid inches.
(a.) Firm; compact; strong; stable; unyielding; as, a solid pier; a solid pile; a solid wall.
(a.) Applied to a compound word whose parts are closely united and form an unbroken word; -- opposed to hyphened.
(a.) Fig.: Worthy of credit, trust, or esteem; substantial, as opposed to frivolous or fallacious; weighty; firm; strong; valid; just; genuine.
(a.) Sound; not weakly; as, a solid constitution of body.
(a.) Of a fleshy, uniform, undivided substance, as a bulb or root; not spongy or hollow within, as a stem.
(a.) Impenetrable; resisting or excluding any other material particle or atom from any given portion of space; -- applied to the supposed ultimate particles of matter.
(a.) Not having the lines separated by leads; not open.
(a.) United; without division; unanimous; as, the delegation is solid for a candidate.
(n.) A substance that is held in a fixed form by cohesion among its particles; a substance not fluid.
(n.) A magnitude which has length, breadth, and thickness; a part of space bounded on all sides.
Example Sentences:
(1) An association of cyclophosphamide, fluorouracil and methotrexate already employed with success against solid tumours in other sites was used in the treatment of 62 patients with advanced tumours of the head and neck.
(2) The sensitivity of 75 non-CNS solid tumors to mismatched dsRNA was compared to the high-grade astrocytomas in the HTCA.
(3) (2) The treated animals ingested less liquid and solid food than controls.
(4) The peptides, which were synthesized using a FMOC solid phase procedure and purified by HPLC, consisted of residues 6-25 from the putative aqueous domain, residues 22-35, which overlaps the putative aqueous and transmembrane domains, and residues 1-38 and 1-40 representing nearly the full length of beta-AP.
(5) We describe an enzymatic fluorometric method for determining glucose concentrations in blood samples by analysis on a semi-solid surface (silicone-rubber pads).
(6) Of all solid tumors only nine occurred in relapse-free patients.
(7) It also showed weak inhibition of the solid type of Ehrlich carcinoma and prolonged the survival period of mice inoculated with L-1210 cells.
(8) Hybridomas were selected on the basis of solid-phase reactivity with the purified native A transferase, cell immunofluorescence and immunoprecipitation of transferase activity, and absence of reactivity with blood group ABH carbohydrate determinants.
(9) The principle of the liquid and solid two-phase radioimmunoassay and its application to measuring the concentrations of triiodothyronine and thyroxine of human serum in a single sample at the same time are described in this paper.
(10) Recently the presence of a coating inhibitory factor was described in human tears which can prevent the binding of proteins to a solid phase.
(11) We therefore conclude that the protective effect displayed by solid grafts might be a local process dependent on the release of diffusible trophic agents.
(12) As a strategy to reach hungry schoolchildren, and increase domestic food production, household incomes and food security in deprived communities, the GSFP has become a very popular programme with the Ghanaian public, and enjoys solid commitment from the government.
(13) The 68-kDa protein of B. bronchiseptica appeared to be the major protective antigen in B. bronchiseptica infection; however, isolated protein alone did not induce such a solid protection, as observed in a previous study after the application of an effective whole cell vaccine.
(14) The median age of patients with bacteremia of unknown origin was 65 years, and their most common underlying disorders were solid malignancy (28% of patients) and diabetes mellitus (18%).
(15) The free energy of activation showed a high negative correlation (r = -0.904, r2 = 0.817) with the percentage of virus adsorption to the solids tested.
(16) It was found that the use of a pH 9.6 buffer during the coating of ELISA plates led to the dissociation of virions into subunits which bound preferentially to the solid phase.
(17) You can tell them that Deutsche Bank remains absolutely rock solid, given our strong capital and risk position.
(18) A solid-phase microtiter assay was developed to investigate the binding properties of the vitronectin receptor.
(20) We conclude that, despite its rarity, adenocarcinomas must be included in the differential diagnosis of solid renal masses in early life.
Substantial
Definition:
(a.) Belonging to substance; actually existing; real; as, substantial life.
(a.) Not seeming or imaginary; not illusive; real; solid; true; veritable.
(a.) Corporeal; material; firm.
(a.) Having good substance; strong; stout; solid; firm; as, substantial cloth; a substantial fence or wall.
(a.) Possessed of goods or an estate; moderately wealthy; responsible; as, a substantial freeholder.
Example Sentences:
(1) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(2) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(3) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(4) Previous studies in this laboratory with particulate Mn3O4 have shown that preweanling rats have substantially higher tissue Mn concentrations than similarly treated adults, indicating possible differences in uptake or elimination or both.
(5) A more substantial decrease was found in Aberdeen and the larger towns near to Aberdeen than in the smaller towns further from the city.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(8) But the amount of time spent above SPA has differed substantially between men and women due to women both living longer, and reaching state pension age earlier.
(9) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(10) Cholestyramine resin was beneficial in reducing stool bulk but had no substantial effect on fat absorption.
(11) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(12) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(13) Mitogen-stimulated cells always contain substantially higher levels of LDL receptor messenger RNA than corresponding resting cells.
(14) Considerable glucose 6-phosphatase activity survived 240min of treatment with phospholipase C at 5 degrees C, but in the absence of substrate or at physiological glucose 6-phosphate concentrations the delipidated enzyme was completely inactivated within 10min at 37 degrees C. However, 80mM-glucose 6-phosphate stabilized it and phospholipid dispersions substantially restored thermal stability.
(15) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(16) The department of dietetics at a large teaching hospital has substantially reduced its food and labor costs through use of computerized systems that ensure efficient inventory management, recipe standardization, ingredient control, quantity and quality control, and identification of productive man-hours and appropriate staffing levels.
(17) Substantial percentages of both physicians and medical students reported access to drugs, family histories of substance abuse, stress at work and home, emotional problems, and sensation seeking.
(18) For further education, this would be my priority: a substantial increase in funding and an end to tinkering with the form of qualifications and bland repetition of the “parity of esteem” trope.
(19) The family members of depressed patients with six or more groups of DSM-III symptoms of major depression exhibited substantially higher rates of mood disorders than the family members of depressed patients with fewer than six groups of symptoms and the family members of patients with nonaffective disorders.
(20) The results presented here substantiate the hypothesis that in S. cerevisiae trehalose supplies energy during dormancy of the spores and not during the germination process.