(a.) Having the constituent parts so compact, or so firmly adhering, as to resist the impression or penetration of other bodies; having a fixed form; hard; firm; compact; -- opposed to fluid and liquid or to plastic, like clay, or to incompact, like sand.
(a.) Not hollow; full of matter; as, a solid globe or cone, as distinguished from a hollow one; not spongy; dense; hence, sometimes, heavy.
(a.) Having all the geometrical dimensions; cubic; as, a solid foot contains 1,728 solid inches.
(a.) Firm; compact; strong; stable; unyielding; as, a solid pier; a solid pile; a solid wall.
(a.) Applied to a compound word whose parts are closely united and form an unbroken word; -- opposed to hyphened.
(a.) Fig.: Worthy of credit, trust, or esteem; substantial, as opposed to frivolous or fallacious; weighty; firm; strong; valid; just; genuine.
(a.) Sound; not weakly; as, a solid constitution of body.
(a.) Of a fleshy, uniform, undivided substance, as a bulb or root; not spongy or hollow within, as a stem.
(a.) Impenetrable; resisting or excluding any other material particle or atom from any given portion of space; -- applied to the supposed ultimate particles of matter.
(a.) Not having the lines separated by leads; not open.
(a.) United; without division; unanimous; as, the delegation is solid for a candidate.
(n.) A substance that is held in a fixed form by cohesion among its particles; a substance not fluid.
(n.) A magnitude which has length, breadth, and thickness; a part of space bounded on all sides.
Example Sentences:
(1) An association of cyclophosphamide, fluorouracil and methotrexate already employed with success against solid tumours in other sites was used in the treatment of 62 patients with advanced tumours of the head and neck.
(2) The sensitivity of 75 non-CNS solid tumors to mismatched dsRNA was compared to the high-grade astrocytomas in the HTCA.
(3) (2) The treated animals ingested less liquid and solid food than controls.
(4) The peptides, which were synthesized using a FMOC solid phase procedure and purified by HPLC, consisted of residues 6-25 from the putative aqueous domain, residues 22-35, which overlaps the putative aqueous and transmembrane domains, and residues 1-38 and 1-40 representing nearly the full length of beta-AP.
(5) We describe an enzymatic fluorometric method for determining glucose concentrations in blood samples by analysis on a semi-solid surface (silicone-rubber pads).
(6) Of all solid tumors only nine occurred in relapse-free patients.
(7) It also showed weak inhibition of the solid type of Ehrlich carcinoma and prolonged the survival period of mice inoculated with L-1210 cells.
(8) Hybridomas were selected on the basis of solid-phase reactivity with the purified native A transferase, cell immunofluorescence and immunoprecipitation of transferase activity, and absence of reactivity with blood group ABH carbohydrate determinants.
(9) The principle of the liquid and solid two-phase radioimmunoassay and its application to measuring the concentrations of triiodothyronine and thyroxine of human serum in a single sample at the same time are described in this paper.
(10) Recently the presence of a coating inhibitory factor was described in human tears which can prevent the binding of proteins to a solid phase.
(11) We therefore conclude that the protective effect displayed by solid grafts might be a local process dependent on the release of diffusible trophic agents.
(12) As a strategy to reach hungry schoolchildren, and increase domestic food production, household incomes and food security in deprived communities, the GSFP has become a very popular programme with the Ghanaian public, and enjoys solid commitment from the government.
(13) The 68-kDa protein of B. bronchiseptica appeared to be the major protective antigen in B. bronchiseptica infection; however, isolated protein alone did not induce such a solid protection, as observed in a previous study after the application of an effective whole cell vaccine.
(14) The median age of patients with bacteremia of unknown origin was 65 years, and their most common underlying disorders were solid malignancy (28% of patients) and diabetes mellitus (18%).
(15) The free energy of activation showed a high negative correlation (r = -0.904, r2 = 0.817) with the percentage of virus adsorption to the solids tested.
(16) It was found that the use of a pH 9.6 buffer during the coating of ELISA plates led to the dissociation of virions into subunits which bound preferentially to the solid phase.
(17) You can tell them that Deutsche Bank remains absolutely rock solid, given our strong capital and risk position.
(18) A solid-phase microtiter assay was developed to investigate the binding properties of the vitronectin receptor.
(20) We conclude that, despite its rarity, adenocarcinomas must be included in the differential diagnosis of solid renal masses in early life.
Topology
Definition:
(n.) The art of, or method for, assisting the memory by associating the thing or subject to be remembered with some place.
Example Sentences:
(1) The scheme is based on topological information, i.e.
(2) These results provide knowledge of the interrelationships between antibiotic and substrate ribosome binding sites which should eventually contribute to a map of ribosomal topology.
(3) The conformational properties of these new TASPs are now under investigation, with special emphasis on the relationship between overall conformation and the nature of the topological template.
(4) In the context of a simplified diamond lattice model of a six-member, Greek key beta-barrel protein that is closely related in topology to plastocyanin, the nature of the folding and unfolding pathways have been investigated using dynamic Monte Carlo techniques.
(5) At the Second Scandinavian Congress on Image Analysis in 1981 Kohonen provided evidence that the map of signals has the same topological order as the map of reactions.
(6) Phylogenetic analysis of the aligned sequences by both phenetic and cladistic methods with H. perryi as an outgroup generated one best topology which pairs S. alpinus with S. malma as the most recently derived species, and pairs S. confluentus with S. leucomaenis.
(7) Then, a 'hyperstructure matrix' is generated, containing the unique topological relationship between every pair of regions.
(8) Linear DNA substrates in which pairing is topologically restricted to a paranemic joint also follow this relationship.
(9) The subgroups of carcinoma of the bladder, determined by topology, have markedly different long-term prognoses.
(10) The fluorescence properties of Hoechst 33342 (HO 33342) were examined with plasmid pBR322 in the supercoiled (Form I) or relaxed covalently closed circular (Form Io) conformation in order to determine whether qualitative or quantitative differences in fluorescence properties might provide an assay for topological states of DNA.
(11) An exhaustive search of all possible trees also supported this topology, although one haplotype had to be eliminated from this analysis to save computer time.
(12) This superfamily of proteins is predicted to share the topology of the seven transmembrane helices of bacteriorhodopsin (BR), even though no significant sequence homology had been identified.
(13) These data demonstrate the utility of this approach for determining membrane protein topology and extend potential applications to include at least some proteins not normally expressed in E. coli.
(14) The unique topology of the products indicates that resolvase fixes the sum of the number of supercoils between recombination sites at synapsis and the number of such supercoils lost or gained during strand exchange.
(15) Such explanations are possible because the relatively few structural proteins of the erythrocyte are regularly distributed over the entire cytoplasmic surface of the cell membrane and because the well-understood topological associations of these proteins seem to be stable in comparison with the time required for the cell to change shape.
(16) The objectives of the present investigations were to document a composite, new approach for the evaluation of the structure-function dependencies of proteins based on the analysis of the informational content of the primary amino acid sequence as well as the topological and functional regions of a protein.
(17) When the input topology is supercoiled, high levels of transcription are observed, whereas input relaxed DNA is transcribed to a much lower extent.
(18) It is believed that one or more basic residues at the extreme amino terminus of precursor proteins and the lack of a net positive charge immediately following the signal peptide act as topological determinants that promote the insertion of the signal peptide hydrophobic core into the cytoplasmic membrane of Escherichia coli cells with the correct orientation required to initiate the protein export process.
(19) We observe that the effect of osmotic shock is an elevation of superhelical tension; quantitative comparison with changes in plasmid linking number indicates that the alteration in DNA topology is all unconstrained.
(20) Anomalous correspondence most probably has its seat where the retinal topology is not exact, i.e., where the binocular receptive fields are very large and encompass the corpus callosum, such as in area 20 or 21.