(a.) Filled with, or showing, spite; having a desire to vex, annoy, or injure; malignant; malicious; as, a spiteful person or act.
Example Sentences:
(1) In spite of dense lymphocytic infiltration only 3% of the tumor infiltrating lymphocytes exhibit the activation marker CD 25.
(2) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
(3) In spite of important differences in size, chemical composition, polymer density, and configuration, biological macromolecules indeed manifest some of the essential physical-chemical properties of gels.
(4) Mastitis in its complexity has managed to forestall all efforts of eradication in spite of years of research, antibiotics and practical control measures.
(5) In spite of antimalaria treatment, with cortisone and then with immuno-depressants, the outcome was fatal with a picture of acute reticulosis and neurological disorders.
(6) In spite of the presence of scar tissue following rhytidectomy, this procedure has been quite successful because of the rich blood supply in that area.
(7) By the GN of non-streptococcal etiology, AA's to the BLSE apparently of other specificity are obtained in some cases, in spite of the absence of antibodies to A-PS.
(8) In spite of the formation of the epoxide intermediate, no binding of [14C]d-limonene equivalents to mouse kidney proteins was observed.
(9) No cases of rheumatic fever and no acute nephritis appeared in spite of the vigorous immune response to both cellular and extracellular antigens of group A streptococci documented in 50% to 80% of patients, suggesting that strain variation may be a feature of rheumatogenicity as well as nephritogenicity of group A streptococcal pharyngitis.
(10) Clinical and inflammatory activity improved in both groups, but consistently more so in the auranofin group, in spite of the greater consumption of local steroids and NSAIDs in the placebo group.
(11) The reported case of fetal infection in spite of previous rubella vaccination of the mother does not discourage the use of rubella vaccine.
(12) Although operative mortality was significantly greater for women during most of this review period, mortality was similar during 1983 (2.6% for men versus 2.4% for women), in spite of a significantly higher incidence of unstable angina in the female group (54% for women versus 35% for men).
(13) The shapes of the curves for soleus and tibialis anterior are similar in spite of the different mechanical conditions of the two muscles.
(14) In spite of the limitations arising from the complex geometry of the right ventricule, echocardiography may be the most important non-invasive technique in the evaluation of the structural and functional repercussion of hypertension on the right ventricle.
(15) Thus, in spite of its excellent activity and unquestionable effectiveness, rifampicin should be used with caution in severe staphylococcal infections.
(16) My son was born healthy, strong and very handsome, in spite of his dangerous start.
(17) The great clinical value of the procedure is shown by the following findings:X-ray-negative lesions--including 2 cases of carcinoma--were found in 35 percent of the cases, radiologically demonstrated lesions could be defined more precisely in 18 percent, and the presence of colonic lesions could be ruled out in 11 percent in spite of equivocal X-ray findings.
(18) In spite of low fluoride content in their water supply, the findings revealed a generally low prevalence of caries experience (DMFT 1.26).
(19) In anesthetized cats, the enhancement of sympathetic activity and increase of the blood pressure in exclusion of afferents (section of vagosympathetic trunks and clamping of common carotid arteries) as well as the disappearance of the activity in enhanced afferentation, were shown to be transient and to disappear within a few minutes-scores of minutes in spite of the going on deafferentation or enhancement of afferentation.
(20) By modifying the spatial distribution of afferents to the network, we demonstrate that the same basic model functions properly in spite of afferents with nonuniform background firing rates.
Willful
Definition:
(a.) Of set purpose; self-determined; voluntary; as, willful murder.
(a.) Governed by the will without yielding to reason; obstinate; perverse; inflexible; stubborn; refractory; as, a willful man or horse.
Example Sentences:
(1) And would all Labour cabinet ministers be as willing to work closely with Lib Dem ministers of state, as happens now, though with some spiky exceptions?
(2) Ender nails as well as three forms of interlocking nails, Brooker-Wills (B-W), Klenm-Schellman (K-S), and Grosse-Kempf (G-K), were implanted in cadaver femora.
(3) Other critics, even if they were unsure of the lasting relevance, were willing to give Tillmans the benefit of the doubt.
(4) It acts as a one-stop shop bringing together credit unions and other organisations, such as Five Lamps , a charity providing loans, and white-goods providers willing to sell products with low-interest repayments.
(5) A system for detecting such cases was established through liaison with other hospital peer review committees or any physician or nurse who was privy to specific information and willing to submit it in writing.
(6) During a time of ongoing industrial action in response to a continuing position of contractual imposition, there is obvious and significant discontent amongst the junior doctor workforce.” Junior doctors are only willing to support the review after the current industrial dispute is resolved, the statement ends.
(7) He also said that at least under the Labour government Gordon Brown had been willing to meet the Argentinians.
(8) Only 4% are willing to face the other option – paying for content with no ads.
(9) In some respects, the impasse is a vindication of the UK electorate’s decision to leave the EU and pursue its own agreements.” He said when the UK government was free to make its own trade deals after leaving the EU, it should target willing partners such as emerging markets.
(10) "We are uncertain of the structure, deliverability and conditionality of what is proposed by Moelis, but we are willing to engage with them to investigate further.
(11) The bill hands £80bn to new GP commissioning boards and will allow any willing provider to compete to provide services.
(12) One of the reasons consumers are willing to take these cases on through the small claims process is because they are not exposed to the other side's costs."
(13) The Fe-protein and the MoFe-protein of the Azotobacter vinelandii nitrogenase complex can be chemically cross-linked by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (Willing, A., Georgiadis, M.M., Rees, D. C., and Howard, J.
(14) During his visit to Europe he did not speak at length on the subject of the shooting, but seemed more willing than Giuliani to distance the Dallas tragedy from the Black Lives Matter movement.
(15) "Only a minority of doctors would be willing to participate in such acts," the authors clear-thinkingly object.
(16) But it is unlikely that we are any more willing to tolerate the negative fallout from regulation today than we were in the 1970s, and therefore we predict that the proportion of GNP going to health care will continue to grow throughout the remainder of this century.
(17) Before the vote was announced, Dimon told shareholders the bank was willing to "pay attention to what we've heard."
(18) The majority of EU delegations are willing to make a compromise on an apology, but some are still unable to accept this."
(19) That is likely to happen under plans by the health secretary, Andrew Lansley , to let "any willing provider" – part of the health service, a private healthcare provider or a charity – be paid out of NHS funds to treat NHS patients.
(20) Christina Wille, director, Insecurity Insight , Bellevue, Switzerland Demand data from those you fund : Gender sensitive donors in humanitarian aid should ask those they fund for better reporting on sex segregated violence.