What's the difference between spleen and splenitis?
Spleen
Definition:
(n.) A peculiar glandlike but ductless organ found near the stomach or intestine of most vertebrates and connected with the vascular system; the milt. Its exact function in not known.
(n.) A sudden motion or action; a fit; a freak; a whim.
(n.) Melancholy; hypochondriacal affections.
(n.) A fit of immoderate laughter or merriment.
(v. t.) To dislke.
Example Sentences:
(1) At the early phase of the sensitization a T-cell response was seen in vitro, characterized by an increased spleen but no peripheral blood lymphocyte reactivity to T-cell mitogens at the same time as increased reactivity to the sensitizing antigen was detected.
(2) Most of the radioactivity in spleen cells from these rats were associated with antigen-reactive cells which formed rosettes specifically with HO erythrocytes.
(3) Reactive metabolites which suppress splenic humoral immune responses are thought to be generated within the spleen rather than in distant tissues.
(4) Pokeweed mitogen-stimulated rat spleen cells were identified as a reliable source of rat burst-promoting activity (PBA), which permitted development of a reproducible assay for rat bone marrow erythroid burst-forming units (BFU-E).
(5) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(6) Moreover, the data showed for the first time that DNA synthesis in the bone marrow and spleen and colon were markedly statistically significantly stimulated at specific times after treatment.
(7) High radioactivities were observed in the digestive organs, mesenteric lymphnodes, liver, pancreas, urinary bladder, fat tissue, kidney and spleen after oral administration to rats.
(8) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(9) Proliferation of quiescent hematopoietic stem cells, purified by cell sorting and evaluated by spleen colony assay (CFU-S), was investigated by measuring the total cell number and CFU-S content and the DNA histogram at 20 and 48 hours of liquid culture.
(10) In investigation of AMLR composed of peripheral blood cells and spleen cells of gastric cancer patient, AMLR on splenic non-T cells as a stimulator was significantly suppressed compared with peripheral blood non-T cells as a stimulator.
(11) During the development of Shvets' leukosis, the weight of spleen and lymph glands and their lymphocyte content change enormously while the number of plasmocytes rises exponentially.
(12) A constellation of histologic lesions was identified in brain (diffuse meningoencephalitis with bilaterally symmetrical thalamic necrosis), liver (pericholangiohepatitis), lung (pneumonitis), and spleen (lymphoid hyperplasia); this tetrad is apparently unique to this model system.
(13) The bursa of Fabricius, thymus glands and spleen of chickens were also shown to express mRNA coding for ANP.
(14) For routine use, 50 mul of 12% BTV SRBC, 0.1 ml of a spleen cell suspension, and 0.5 ml of 0.5% agarose in a balanced salt solution were mixed and plated on a microscope slide precoated with 0.1% aqueous agarose.
(15) Polyadenylic-polyuridylic acid complexes (poly A:U) at the 1-5 mu g level, were mitogenic for spleen cells when given intravenously to normal Balb or cortisone-treated mice.
(16) Mixing experiments were performed to test the putative inhibitory effects of allotype-suppressed spleen cells from the first adoptive transfer (stage I) on the antibody response of normal spleen cells in a second adoptive transfer (stage II).
(17) After birth, it was in the liver and spleen up to 6 weeks af age, and thereafter it was present only in the bone marrow.
(18) Only the group that received 3R spleen cells treated with anti I-Jb monoclonal antibody and C' had no suppressed PFC.
(19) Prior incubation of these antigens with test spleen cells in the agar gel effictively inhibited development of the vibriolytic plaques, regardless of antibody class.
(20) Four hours after injection radioactivity was identified in the spleen, liver, and bone marrow.
Splenitis
Definition:
(n.) Inflammation of the spleen.
Example Sentences:
(1) A suppurative gastritis with full thickness perforations of the stomach wall associated with Gasterophilus intestinalis larvae had extended to the juxtaposed organ initiating an extensive suppurative splenitis.
(2) Quails developed necrotizing tracheitis, proliferative and necrotizing bronchitis and pneumonia; multifocal necrotizing hepatitis; necrotizing splenitis, with or without hyperplasia of splenic mononuclear phagocytes; bursal lymphoid necrosis; and bursal atrophy.
(3) Groups 1, 2, and 4 consistently showed pneumonitis and splenitis.
(4) Nocardia asteroides was isolated from one koala with extensive pneumonia, pleurisy and splenitis.
(5) Microscopic findings included nematodiasis, microfilariasis, lymphadenitis, lymphangiectasis, perilymphangitis, splenitis, orchitis, periorchitis, epididymitis and funiculitis.
(6) The test group also exhibited acute splenitis, including microabscesses, and two of four test animals showed hepatic congestion, vacuolization of hepatocytes, and microabscesses.
(7) This is the first human case report of an acute necrotizing splenitis resulting from B. burgdorferi.
(8) In both cases, there was granulomatous hepatitis as well as splenitis.
(9) Although severe focal lesions due to dead and disintegrating worms were present in the livers of the treated animals, no aggravation of the general changes (reactive hepatitis and splenitis, or periovular granulomas) was seen in comparison with a control non-treated group.
(10) In addition to a previously reported and often fatal acute interstitial pneumonitis, S. falcatula-infected budgerigars also sustained a chronic active hepatitis, interstitial myocarditis, myositis, nephritis, splenitis, and encephalitis.
(11) In animals dying of the infection, a severe necrotizing splenitis was present.
(12) Pathologic findings in the coyote and dog were similar; both animals had splenitis, lymphadenitis, and petechiation of the lungs.
(13) In 11 calves the spleen was distinctly smaller than normal and its morphology was distorted, and showed changes of chronic splenitis.
(14) Severe changes of reactive hepatitis and splenitis appeared suddenly when the first mature eggs were deposited, around the 37th to 42nd day after infection.
(15) Peri-splenitis accompanies severe hepatitis (3 cases) and no perinephritis was observed in this study.
(16) Lesions produced by either route of inoculation were similar to those of quail bronchitis and included necrotizing tracheitis, proliferative and necrotizing bronchitis and pneumonia, and multifocal necrotizing hepatitis, necrotizing splenitis with or without hyperplasia of splenic macrophages, and lymphoid necrosis and atrophy of the bursa of Fabricius.
(17) In a review of the literature the problems associated with purulent splenitis and the possibility of treating it by percutaneous puncture are pointed out.
(18) At surgery 3 patients were found to have Mycobacterium avium intracellulare (MAI) infection; 2 had splenic abscess due to Salmonella group D; 1 each had cytomegalovirus (CMV) splenitis and localized Kaposi's sarcoma (KS) of the spleen.
(19) The major microscopic lesions were acute suppurative placentitis and splenitis.
(20) The ichorous splenitis revealed by the post-mortem studies was not observed on clinical examination.