(v. t.) To unite, as two ropes, or parts of a rope, by a particular manner of interweaving the strands, -- the union being between two ends, or between an end and the body of a rope.
(v. t.) To unite, as spars, timbers, rails, etc., by lapping the two ends together, or by applying a piece which laps upon the two ends, and then binding, or in any way making fast.
(v. t.) To unite in marrige.
(n.) A junction or joining made by splicing.
Example Sentences:
(1) It is argued that this process drove the evolution of present 5' and 3' splice sites from a subset of proto-splice sites and also drove the evolution of a more efficient splicing machinery.
(3) One splicing mutation results in a 3 amino acid in-frame insertion.
(4) Each of the two spliced molecules contains a 5'-terminal leader sequence transcribed from a DNA segment with an estimated length of 60 to 110 nuvleotides.
(5) Previously, we identified a candidate gene, Tcp-10b, whose t allele generates alternatively spliced transcripts.
(6) Analysis of this mutant illustrates that indirect flight muscles and jump muscles utilize different mechanisms for alternative RNA splicing.
(7) A comparison between the primary structures of the rat and human genes reveals that the heterogeneity of the C-terminal peptides can be explained in large part by a frameshift mutation and the utilization of an alternative splice donor site in the third exon of the rat gene.
(8) A new alternative splice site was incidently found 81 nucleotide downstream of motif II in both normal and truncated 4.1 mRNA.
(9) The IGA-65 present in splicing extracts was distinguishable from known U-snRNP and hnRNP proteins on protein gels.
(10) The protein variation potentially includes N-terminal differences coded for by transcript-specific 5' exons and internal differences arising from the optional inclusion of a 39 base-pair exon and from the alternative use of two 3' splice sites separated by six base-pairs.
(11) Certain RNA molecules can mediate their own cleavage or splicing or act as enzymes to promote reactions on substrate RNA molecules.
(12) In order to identify putative protein splicing factors associated with the 200S InRNP particles, a panel of monoclonal antibodies directed against these particles were screened for their ability to inhibit splicing of pre-mRNA in vitro.
(13) Similar results were obtained when hybrid-selected RNA, which had been labeled for 3 h with [3H]uridine, was analyzed on formaldehyde-agarose gels, suggesting that the observed differences were due to splicing rather than RNA stability.
(14) At the restrictive temperature the ratio of unspliced U6 precursor to mature RNA is elevated in the mutants compared to the wild type grown under identical conditions, indicating a defect in U6 pre-RNA splicing.
(15) These two splicing intermediates cosedimented under a variety of conditions, indicating that they are contained in the same RNP complex.
(16) Recombinant retroviruses containing intact or spliced CRPV sequences can now be used to introduce the viral genes efficiently into a variety of cell lines.
(17) The 0.85 kb fragment was cloned and sequenced and the result indicated that the introns from the xylanase gene were accurately spliced by the plant cells.
(18) The RNA-catalysed self-splicing reaction of group II intron RNA is assumed to proceed by two consecutive transesterification steps, accompanied by lariat formation.
(19) U1 snRNA is an essential splicing factor known to base pair with 5' splice sites of premessenger RNAs.
(20) We have used such constructs, assayed by transient expression in chicken embryo fibroblasts, to define the minimal sequences necessary to inhibit splicing.
Spline
Definition:
(n.) A rectangular piece fitting grooves like key seats in a hub and a shaft, so that while the one may slide endwise on the other, both must revolve together; a feather; also, sometimes, a groove to receive such a rectangular piece.
(n.) A long, flexble piece of wood sometimes used as a ruler.
Example Sentences:
(1) This paper addresses the latter assumption by applying a direct and flexible approach, cubic spline functions, to two widely used models: the logistic regression model for binary responses and the Cox proportional hazards regression model for survival time data.
(2) After filament images were straightened by spline-fitting, several transforms showed well-defined layer-lines arising from the helical structure of the filament.
(3) We have compared three interpolation methods (surface splines, spherical splines and tridimensional interpolation functions).
(4) The smoothing B-spline function was applied to 3, 10, 25, 50, 75, 90, and 97 percentile TW2 RUS, carpal and 20-bone scores.
(5) The four parameter logistic method, which is based on an approximation of the mass action law, performed better than the Spline method, a procedure which makes no a priori assumptions about the data.
(6) The first and second derivatives of progress curves are obtained from the cubic spline function.
(7) To improve the qualitative and quantitative analysis of surfaces of protein, two new methods are proposed: one that smoothes the MS surface of Connolly with B-spline smoothing functions to highlight the significant features of the surface, and one that computes the density of surface neighborhood to allow quantitative comparison.
(8) In the model, patellofemoral joint profiles projected on a horizontal plane have been expressed as spline functions.
(9) It was demonstrated that by using a least-squares surface-fitting technique, the SPG data on the surface can accurately be described by a single parametric biquintic spline function.
(10) Approximating the signal with a linear combination of cubic B-splines with equally spaced knots, according to the linear least-squares criterion gives the desired data reduction and an elegant way to perform an automatic analysis.
(11) The practical implementation of a rapid Catmull-Rom (cardinal) spline is described, and its advantages with respect to speed and ease of use are discussed.
(12) One of these is the procedure known as one of the best automatic smoothing and differentiating techniques: generalised cross validatory spline smoothing and differentiation (GCVC).
(13) Splines, were invented nearly 30 years ago and have been shown to have desirable properties.
(14) The spline technique is superior in accuracy to sampling at eight-times the Nyquist rate and is comparable to a Fourier-transform-based interpolation algorithm.
(15) Lines representing linear regression, log-linear regression or quadratic regression were inferior to those described by linear splines.
(16) Although spline functions are by no means unknown to demographers, no simple and direct explanation of their application exists.
(17) The spline technique was used to analyse these data as continuous variables, and showed that the 'super-obese' group of families was too small to be of any practical importance.
(18) Using penalized likelihood the three curves can be fitted as cubic splines by non-linear regression, and the extent of smoothing required can be expressed in terms of smoothing parameters or equivalent degrees of freedom.
(19) In general, the bilinear and bicubic spline methods of interpolation perform about equally.
(20) The folding pathway is defined by piecewise B-spline curves and the atoms are initially positioned with respect to the local Frenet trihedra determined by the equations of the curves.