(1) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(2) Steep longitudinal and transverse gradients of glycogen are known to exist in the organ of Corti of the guinea pig, with preferential accumulation in the outer hair cells of the apical turns.
(3) The steep portion of the relationship between Retzius cell action potential amplitude and membrane potential extrapolated to an apparent reversal potential of -13 mV.
(4) This property of endotoxin can serve as a sensitive bioassay, although the dose-response curve is steep.
(5) With its steep hills and cobblestones, the neighbourhood of São Cristóvão in Ouro Preto isn’t an easy place to play football.
(6) Four patients with herpes zoster ophthalmicus developed peripheral corneal ulcers with steep central edges.
(7) The results showed that measurements of impression profiles and SEM photogrammetry gave the most accurate results adjacent to regions simulating steep cavity margins, whereas the profilometric technique gave erroneous results in these regions.
(8) The intensity dependence of the early ganglion cell discharge, its latency and initial impulse frequency, is shown to follow from such a waveform, assuming that 1) latency L = l + D, where l is the time it takes for the rod response linearly summed over the ganglion cell's receptive field to reach a criterion amplitude, and D is a constant delay; and 2) the initial frequency (below saturation) is proportional to the steepness of rise of the summed rod response at time l. It is shown that the intensity dependences of 1) human visual latency and 2) brightness sensation, including effects of stimulus area and duration, are accounted for by the same model.
(9) The new protocol (standardised exponential exercise protocol, STEEP) is suitable for use on either a treadmill or a bicycle ergometer.
(10) Based on the signals observed by organ absorbance spectrophotometry from two compartments with oxidases of markedly different O2 sensitivity, the mitochondria and the peroxisomes, a distribution between high O2 and zero O2 zones is postulated, an intermediate border zone of O2 concentrations between the K0,5 (O2) values being virtually absent (steep intercellular O2 gradients).
(11) A man who had been near them reached the hotel terrace first, scrambling up a steep sandy bank.
(12) Patients with steep sloping audiograms understand better and patients with a conductive hearing loss component understand less in noisy circumstances with a hearing aid.
(13) The operational values are useful in characterising the steepness of dose-incidence curves for normal tissue injury after different fractionation schedules.
(14) Scarborough council said leaving the houses standing could cause a domino-effect down the steep slope above the picturesque harbour where the explorer Captain James Cook lodged and learned his seafaring skills.
(15) It is shown that this individual exhibits approximate alignment of her photoreceptors with the center of the retinal sphere, clear evidence of side lobes on functions, and surprisingly steep SCE I functions.
(16) For cross-linked alpha alpha, however, the curve sags at temperatures somewhat below the region of principal cooperative loss of helix, the latter occurring at higher temperature but with the same steepness as in the non-cross-linked case.
(17) A reduced venous compliance (VC) and inadequate venoconstriction may impair hemodynamics during hemodialysis, the first by impairing plasma volume preservation and by inducing a steep fall in central venous pressure (CVP) during minor plasma volume loss, the second by inadequate mobilization of hemodynamically inactive blood volume.
(18) A generally similar pattern is seen in healthy controls and in patients with untreated pulmonary tuberculosis, treated leprosy, haemophilia A and chronic obstructive lung disease (COLD) patients treated with prednisolone, but the gradient of increasing CD4:CD8 ratio with depth into the dermis is significantly less steep in patients with tuberculosis, haemophilia and prednisolone-treated COLD than in the healthy controls.
(19) Some problem drugs may be recognized if they display one or more of the following characteristics: narrow therapeutic index, steep dose-effect relationship, nonlinear kinetics, variable bioavailability, and pharmacogenetically determined kinetics.
(20) Replacement of a half of Ca++ ions by Sr++ resulted in an augmentation of steepness of the dependence on sum of [Ca++] and [Sp++], and in a more prominent fall in relaxation velocity as compared with contraction velocity.
Stepped
Definition:
(imp. & p. p.) of Step
(a.) Provided with a step or steps; having a series of offsets or parts resembling the steps of stairs; as, a stepped key.
Example Sentences:
(1) These data suggest that the hybrid is formed by the same mechanism in the absence and presence of the urea step.
(2) That means deciding what job they’d like to have and outlining the steps they’ll need to take to achieve it.
(3) Enhanced sensitivity to ITDs should translate to better-defined azimuthal receptive fields, and therefore may be a step toward achieving an optimal representation of azimuth within the auditory pathway.
(4) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(5) Training in social skills specific to fostering intimacy is suggested as a therapeutic step, and modifications to the social support measure for future use discussed.
(6) To explore an early step, we synthesized 5 beta-cholest-7-ene-3 beta,6 alpha,14 alpha-triol in tritiated form.
(7) Change of steps in achieved just by varying the reaction conditions without any product purification.
(8) Yesterday's flight may not quite have been one small step for man, but the hyperbole and the sense of history weighed heavily on those involved.
(9) After immunoadsorbent purification, the final step in a purification procedure similar to that adopted for colon cancer CEA, two main molecular species were identified: 1) Material identical with colon cancer CEA with respect to molecular size, PCA solubility, ability to bind to Con A, and most important the ability to bind to specific monkey anti-CEA serum.
(10) The stepped approach is cost-effective and provides an objective basis for decisions and priority setting.
(11) "These developments are clearly unwarranted on the basis of economic and budgetary fundamentals in these two member states and the steps that they are taking to reinforce those fundamentals."
(12) We describe both the three supportive psychotherapeutic steps, which may last months to years including subsequent dynamically psychotherapeutic strategies as well as the reactions of the auxiliary therapist function on the students.
(13) It is also a clear sign of our willingness and determination to step up engagement across the whole range of the EU-Turkey relationship to fully reflect the strategic importance of our relations.
(14) As calls grew to establish why nobody stepped in to save Daniel, it was also revealed that the boy's headteacher – who saw him scavenging for scraps – has not been disciplined and has been put in charge of a bigger school.
(15) Problem definition, the first step in policy development, includes identifying the issues, discussing and framing the issues, analyzing data and resources, and deciding on a problem definition.
(16) The influence of vestibular dysfunction upon the vestibulospinal reflex (VSR) in two common peripheral syndromes was investigated by two types of posturographic examination: "static" posturography, recording and analyzing the postural sway in stance, and "kinetic" posturography, recording the stepping in place test.
(17) The second step occurs several hours later and consists of the transactivation of adenylate cyclase and pertussis toxin genes.
(18) Western diplomats acknowledge that the capture of Qusair is likely to have emboldened President Bashar al-Assad , making him less likely to consider concessions – let alone stepping down.
(19) The influence of exogenous mitogens (RFG, TGF beta 1 and insulin) and autocrine factor (at different step of purification) on the growth of Morris hepatoma 7777 (MH) cells was estimated by both methods.
(20) An experience in working out and introduction of a system of failure-free performance work as one of the most important steps in creating a complex system for the production quality control at the Leningrad combine "Krasnogvardeets" is described.