(superl.) Not easily bent; not flexible or pliant; not limber or flaccid; rigid; firm; as, stiff wood, paper, joints.
(superl.) Not liquid or fluid; thick and tenacious; inspissated; neither soft nor hard; as, the paste is stiff.
(superl.) Firm; strong; violent; difficult to oppose; as, a stiff gale or breeze.
(superl.) Not easily subdued; unyielding; stubborn; obstinate; pertinacious; as, a stiff adversary.
(superl.) Not natural and easy; formal; constrained; affected; starched; as, stiff behavior; a stiff style.
(superl.) Harsh; disagreeable; severe; hard to bear.
(superl.) Bearing a press of canvas without careening much; as, a stiff vessel; -- opposed to crank.
(superl.) Very large, strong, or costly; powerful; as, a stiff charge; a stiff price.
Example Sentences:
(1) If you turn the bowl upside down, the whites should be stiff enough not to fall out.
(2) The stiffness of the fibre first rose abruptly in response to stretch and then started to decrease linearly while the stretch went on; after the completion of stretch the stiffness decreased towards a steady value which was equal to that during the isometric tetanus at the same sarcomere length, indicating that the enhancement of isometric force is associated with decreased stiffness.
(3) Current methodology for the in vitro determination of aortic and large artery stiffness is reviewed and involves three approaches: (1) the estimation of distensibility by pulse wave velocity measurement; (2) the estimation of distensibility from the fractional diameter change of a given arterial segment by imaging techniques (e.g., angiography, Doppler ultrasound) against pressure change; (3) the estimation of compliance by determining volume change against pressure change in the arterial system during diastolic runoff from the Windkessel model of the circulation.
(4) The maintenance of adequate blood circulation requires a sufficient ventricular contractility; in addition, to eject blood, the ventricles must first receive a sufficient volume, requiring a low diastolic stiffness.
(5) Stiffness was reduced in approximate proportion to the ramp stretch rate, and the reduction was confined largely to the elastic component.
(6) Proof stress, ultimate tensile strength, elongation, and plastic stiffness have been measured and results compared by use of analyses of variance.
(7) In other words, the stiffness of these areas was low and the recovery from deformation was fast.
(8) But the same court also just refused to hear an appeal of a Minnesota woman who's been ordered to pay more than $220,000 for downloading two-dozen songs – a testament to Congress' gift to Hollywood and its allies in the form of absurdly stiff penalties for minor infringement.
(9) The tension-length relation for the unstimulated (passive) cell is also linear between 1r and the elastic limit, but is displaced from the active tension-length curve and is of reduced stiffness.
(10) Bilaterals in summit seasons can be stiff exchanges, where digressions can carry risks: not enough said, too much said.
(11) We measured the stiffness of comparable configurations (1 or 2 bars) under axial compression, four-point-bending in two planes, and torsion.
(12) Tiny, tiny... rodents – some soft and grey, some brown with black stripes, in paintings, posters, wallcharts, thumb-tacked magazine clippings and poorly executed crayon drawings, hurling themselves fatally in their thousands over the cliff of their island home; or crudely taxidermied and mounted, eyes glazed and little paws frozen stiff – on every available surface.
(13) The bone stiffness also correlates strongly with the geometry (area) and slightly with bone mass; however, an unexpectedly low correlation was found between stiffness and density.
(14) Finally, fibrosis may paradoxically reduce passive stiffness if it leads to a thinning of the interventricular septum.
(15) A young male nephrotic patient, who was given small doses of clofibrate for hyperlipaemia, developed muscle pain, stiffness and very high serum levels of muscle enzymes.
(16) Impaired left ventricular stiffness may be an additional criterion for using corinfar in patients with coronary heart disease.
(17) The increase of elastic fibres following denervation and reinnervation represents an obviously meaningful reaction that may compensate for loss of tonic properties of muscle spindles without causing stiffness.
(18) Only the bone-patellar tendon-bone unit had maximum force and stiffness greater than that of the ACL.
(19) The initial stiffness is poorly described by material or catheter gauge.
(20) The stiffness tester and torque meter were found to yield nearly the same measurements of bending deformation for orthodontic wires as small as .007 inch diameter, provided the different bending apparatus are calibrated to each other.
Tight
Definition:
() of Tie
() p. p. of Tie.
(superl.) Firmly held together; compact; not loose or open; as, tight cloth; a tight knot.
(superl.) Close, so as not to admit the passage of a liquid or other fluid; not leaky; as, a tight ship; a tight cask; a tight room; -- often used in this sense as the second member of a compound; as, water-tight; air-tight.
(superl.) Fitting close, or too close, to the body; as, a tight coat or other garment.
(superl.) Not ragged; whole; neat; tidy.
(superl.) Close; parsimonious; saving; as, a man tight in his dealings.
(superl.) Not slack or loose; firmly stretched; taut; -- applied to a rope, chain, or the like, extended or stretched out.
(superl.) Handy; adroit; brisk.
(superl.) Somewhat intoxicated; tipsy.
(superl.) Pressing; stringent; not easy; firmly held; dear; -- said of money or the money market. Cf. Easy, 7.
(v. t.) To tighten.
Example Sentences:
(1) Freshly isolated sarcoplasmic reticulum vesicles contain 0.05 mol of tightly bound ADP and 0.03 mol of tightly bound ATP per mol of Ca2+, Mg2+-ATPase (ATP phosphohydrolase, EC 3.6.1.3).
(2) The expression of the Pgp isoforms appears to be tightly regulated and, at least in some cells, under complex hormonal control.
(3) Whereas the tight junctions of endoneurial capillaries are known to prevent certain blood-borne substances from entering the endoneurium, it was not clear whether the permeability of the pulpal capillaries, which are distant from the nerve fibres, could affect the nerve fibre environment.
(4) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(5) These data indicate that topoisomerase I and RNA polymerase I are tightly complexed both in vivo and in vitro, and suggest a role for DNA topoisomerase I in the transcription of ribosomal genes.
(6) Immunofluorescence and immunoelectronmicroscopy experiments demonstrated that while tight junctions demarcate PAS-O distribution in confluent cultures, apical polarity could be established at low culture densities when cells could not form tight junctions with neighboring cells.
(7) Investigations have been made to determine the identity and binding characteristics of the pterins that are bound tightly to dihydrofolate reductases which are isolated from vertebrate sources by a well established procedure.
(8) At all times, a tight inverse correlation exists between ATP and IMP concentrations.
(9) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).
(10) This study investigates the use of the incentive inspirometer to observe the effects of tight versus loose clothing on inhalation volume with 17 volunteer subjects.
(11) In contrast, interchange of the histones and tightly bound non-histone protein DNA complexes from hormone-withdrawn and estrogen-stimulated chromatins during reconstitution did not affect the level of mRNAOV sequences produced.
(12) Using microelectrodes and various microscopic techniques active Na+ absorption as well as K+ secretion has been localized to the principal cells, while Cl- absorption was found to proceed largely, though not exclusively, through the tight junctions between cells.
(13) The successful establishment of a postcrisis SV-40 T antigen transformed epithelial cell line, 1HAEo-, which retains tight junctions and vectorial ion transport, is described.
(14) The present investigation shows that the intramembranous proteins of tight and gap junctions are mobile structures within the fluid membrane.
(15) In contrast, after incubation with 0.5% DOC, the core microfilaments are no longer tightly bundled yet the lateral arms remain attached with a distinct 33-nm periodicity.
(16) The data collected by several approaches reveal that assembly and maturation of vaccinia involves a tightly coupled sequence of interrelated events including the assembly of the envelope, post-translational cleavage of several virion polypeptides, and induction of the core enzymes.
(17) The tight coupling between neuronal activity and oxidative energy metabolism forms the basis for the use of cytochrome oxidase as an endogenous metabolic marker for neurons.
(18) When using a nylon thread for the attachment of a pseudophakos to the iris, it may happen that the suture is slung tightly around the implant-lens.
(19) Some antibodies and other proteins bind tightly to nitrocellulose and dissociation of these proteins by Tween 20 is barely detectable.
(20) Independent experts warn that rumours and deliberate misinformation about the regime are rife, partly because it is impossible to verify or disprove most stories about the tightly controlled country's elite.