(n.) That which underlies all outward manifestations; substratum; the permanent subject or cause of phenomena, whether material or spiritual; that in which properties inhere; that which is real, in distinction from that which is apparent; the abiding part of any existence, in distinction from any accident; that which constitutes anything what it is; real or existing essence.
(n.) The most important element in any existence; the characteristic and essential components of anything; the main part; essential import; purport.
(n.) Body; matter; material of which a thing is made; hence, substantiality; solidity; firmness; as, the substance of which a garment is made; some textile fabrics have little substance.
(n.) Material possessions; estate; property; resources.
(n.) Same as Hypostasis, 2.
(v. t.) To furnish or endow with substance; to supply property to; to make rich.
Example Sentences:
(1) No differences between the two substances were observed with respect to side effects and general tolerability.
(2) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(3) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
(4) Intracellular localization of the labeled substance in the tumor tissue was examined autohistoradiographically.
(5) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(6) A substance with a chromatographic mobility of Rf = 0.8 on TLC plates having an intact phosphorylcholine head group was also formed but has not yet been identified.
(7) Serum pepsinogen 1, serum gastrin, ABO blood groups, secretor status of ABH blood group substances and behavioral factors were studied in 15 patients with duodenal ulcer and 61 their relatives affected and unaffected to duodenal ulcer.
(8) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.
(9) Urine tests in six patients with other kidney diseases and with uraemia and in seven healthy persons did not show this substance.
(10) Substance P, a potent vasodilating peptide, seems to be released from trigeminal nerve endings in response to nervous stimulation and is involved in the transmission of painful stimuli within the periphery.
(11) Regulators concerned about physician behavior and confronted by demands of nonphysicians to prescribe controlled substances may find EDT a good solution.
(12) These results are discussed in the light of the mode of action of the substances used.
(13) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(14) We have investigated some of the factors which affect the retention times of these substances in reversed-phase HPLC on columns of 5-micron octadecylsilyl silica.
(15) The data indicate that adult neurons with an intrinsic ability to regenerate axons can respond to substances with neurotrophic or neurite-promoting activities in tissue cultures.
(16) The authors describe the role played by these substances in the pathogenesis of inflammations, their importance in the regulation of intraocular pressure and in the development of cystoid macular oedema.
(17) They were more irregularly curved and consisted of various substances.
(18) We examined 10 life areas clustered around the general categories of "substance use," "social functioning," and "emotional and interpersonal functioning."
(19) In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis.
(20) The following possible explanations were discussed: a) the tested psychotropic drugs block prostaglandin receptors in the stomach; b) the test substances react with prostaglandin in the nutritive solution; c) the substances stimulate metabolic processes in the stomach wall that break down prostaglandin.
Substantive
Definition:
(a.) Betokening or expressing existence; as, the substantive verb, that is, the verb to be.
(a.) Depending on itself; independent.
(a.) Enduring; solid; firm; substantial.
(a.) Pertaining to, or constituting, the essential part or principles; as, the law substantive.
(n.) A noun or name; the part of speech which designates something that exists, or some object of thought, either material or immaterial; as, the words man, horse, city, goodness, excellence, are substantives.
(v. t.) To substantivize.
Example Sentences:
(1) Alternatives for the selection of substantive clinical attributes, the overall structural format into which categories are organized, and construction procedures used in developing a psychopathologic taxonomy are elaborated, as are a number of criteria for evaluating the taxonomy's utility and efficacy.
(2) Further it is argued that there is a need to amalgamate the substantive, conceptual, and methodological facets of research.
(3) Among the implications of the less-than-impressive substantive results of the MWTA is the lesson that while a crisis can tilt the political balance in favor of regulatory legislation, it cannot as readily produce the consensus required to sustain that regulation at the levels promised in the legislation.
(4) Wicker's (this issue) article on substantive theorizing outlines an approach to theory and research that helps communicate the structure and process of doing research on a complex area.
(5) Our findings demonstrate the long lasting substantivity of doxycycline hydrochloride on periodontally diseased root surfaces and supports the concept of using root surfaces as a substrate for the deposition and slow release for local tetracycline delivery.
(6) Twenty-five years of persistent research at the Jena Institute of Bacterial Animal Diseases have yielded substantive results of relevance to general knowledge and veterinary practice in the following fields: Mycoplasma species in farm animals-isolation, demands on culturing substrate, and differentiation; Virulence testing; Development, production, and application of diagnostic preparations; Development to full application maturity of diagnostic techniques and concepts for control of several mycoplasmal infections of relevance in terms of economy.
(7) Redesigning the dream was identified as the integrative theme in the substantive theory that described how family members gradually modify their beliefs about organ transplantation and develop attitudes and beliefs to meet the challenge of living with continual unpredictability.
(8) These data suggest that although a shortened form of the HIT may be useful with aged persons, research exploring the substantive bases for creating a shortened version of the HIT is nevertheless necessary.
(9) Unfortunately, a large number of potential compounds are unsuitable for use in dentifrices because they lack "substantivity", produce undesirable side-effects, or are incompatible with toothpaste ingredients.
(10) Methodological and substantive recommendations for future research are made and a discussion of possible mechanisms is presented.
(11) When the influence of castration on adduct formation was investigated, adduct levels in kidneys of castrated females were higher than those in sham-operated females, but adduct levels in kidneys of the castrated male animals were not substantively different from those seen in sham-operated male controls.
(12) Based on a discrete-time hazard modeling approach, the results substantiate that the occupational task activities--substantive complexity and physical demands--are key elements of the work environment that are evaluated against nonwork alternatives.
(13) "I think when critics don't have a substantive alternative to offer they reach for the 'out of touch' criticism," he said.
(14) Findings revealed two substantive processes, the touching process and acquiring a touching style, neither of which has been previously reported.
(15) Quantitative information is the substantive input to decisions on whether oral and maxillofacial surgeons wish to go where they appear to be going, and if so why, and if not, why not?
(16) The Kinnaird report was very critical of defence acquisition processes up to that point, because approval had often been “sought before whole-of-life costs are well defined and, for many projects, prior to substantive engagement with industry.
(17) What came out instead was a substantive document, involving concrete steps towards defusing the crisis.
(18) But political will to uplift the lot of women substantively was lacking.
(19) But I reckon Laura Tingle is dead right on the substantive challenge - the statement just shows the country can no longer coast.
(20) The union's assistant general secretary Diana Holland said: "We will not be calling Easter strike action as we focus on substantive talks through Acas.