(n.) That which underlies all outward manifestations; substratum; the permanent subject or cause of phenomena, whether material or spiritual; that in which properties inhere; that which is real, in distinction from that which is apparent; the abiding part of any existence, in distinction from any accident; that which constitutes anything what it is; real or existing essence.
(n.) The most important element in any existence; the characteristic and essential components of anything; the main part; essential import; purport.
(n.) Body; matter; material of which a thing is made; hence, substantiality; solidity; firmness; as, the substance of which a garment is made; some textile fabrics have little substance.
(n.) Material possessions; estate; property; resources.
(n.) Same as Hypostasis, 2.
(v. t.) To furnish or endow with substance; to supply property to; to make rich.
Example Sentences:
(1) No differences between the two substances were observed with respect to side effects and general tolerability.
(2) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(3) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
(4) Intracellular localization of the labeled substance in the tumor tissue was examined autohistoradiographically.
(5) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(6) A substance with a chromatographic mobility of Rf = 0.8 on TLC plates having an intact phosphorylcholine head group was also formed but has not yet been identified.
(7) Serum pepsinogen 1, serum gastrin, ABO blood groups, secretor status of ABH blood group substances and behavioral factors were studied in 15 patients with duodenal ulcer and 61 their relatives affected and unaffected to duodenal ulcer.
(8) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.
(9) Urine tests in six patients with other kidney diseases and with uraemia and in seven healthy persons did not show this substance.
(10) Substance P, a potent vasodilating peptide, seems to be released from trigeminal nerve endings in response to nervous stimulation and is involved in the transmission of painful stimuli within the periphery.
(11) Regulators concerned about physician behavior and confronted by demands of nonphysicians to prescribe controlled substances may find EDT a good solution.
(12) These results are discussed in the light of the mode of action of the substances used.
(13) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(14) We have investigated some of the factors which affect the retention times of these substances in reversed-phase HPLC on columns of 5-micron octadecylsilyl silica.
(15) The data indicate that adult neurons with an intrinsic ability to regenerate axons can respond to substances with neurotrophic or neurite-promoting activities in tissue cultures.
(16) The authors describe the role played by these substances in the pathogenesis of inflammations, their importance in the regulation of intraocular pressure and in the development of cystoid macular oedema.
(17) They were more irregularly curved and consisted of various substances.
(18) We examined 10 life areas clustered around the general categories of "substance use," "social functioning," and "emotional and interpersonal functioning."
(19) In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis.
(20) The following possible explanations were discussed: a) the tested psychotropic drugs block prostaglandin receptors in the stomach; b) the test substances react with prostaglandin in the nutritive solution; c) the substances stimulate metabolic processes in the stomach wall that break down prostaglandin.
Tenuous
Definition:
(a.) Thin; slender; small; minute.
(a.) Rare; subtile; not dense; -- said of fluids.
(a.) Lacking substance, as a tenuous argument.
Example Sentences:
(1) Diagnosis based on the character of the stridor alone is tenuous, and consideration of presentation other than the stridor is discussed in the management of these infants.
(2) Indian women are aware of our tenuous grip on our rights.
(3) Rising losses among the nearly 350,000-strong Afghan army and police, and a desertion rate of about 50,000 a year, also support Karzai's contention that control of large parts of the country remains tenuous.
(4) The results suggest that chronic sunlight exposure may be associated with an impediment to normal maturation of human dermal collagen resulting in tenuous amount of HHL.
(5) What the film does, though, is use these incidents to build an idiosyncratic but insightful picture of Lawrence, played indelibly by Peter O'Toole in his debut role: a complicated, egomaniacal and physically masochistic man, at once god-like and all too flawed, with a tenuous grip both on reality and on sanity.
(6) Because of disruption of the fasciocutaneous circulation, the perfusion of randomly based flaps is frequently tenuous.
(7) New employment data today suggested that hurricane Sandy is hurting already tenuous US job growth.
(8) Although extrapolation from animal studies may be tenuous, the present findings may explain the link between nutrition and the occurrence of alcoholic pancreatitis.
(9) If any of them is neglected or isolated from the rest, the whole will be impoverished-the student will suffocate in disconnected, empirical facts; fanciful theories will be spun from tenuous evidence; well established theory will be neglected by the practitioner; the best-intentioned schemes will have disastrous long-term consequences.
(10) However, circumstantial evidence is beginning to provide a tenuous link between smoking and the protease-antiprotease imbalance hypothesis.
(11) Though one possible mechanism for this reversal may include the inhibition of NAD-kinase by cAMP, there is evidence to suggest that such a direct cause-effect relationship is at present tenuous.
(12) We feel that tenuous attachments of the vitreous body to the fovea could exert traction on the vitreo-retinal interface or shrinkage of a fibrocellular membrane on the inner foveal surface could lead to the observations made by us.
(13) As has been long predicted by military critics of a bombing campaign, Mayville said Isis was already changing its tactics in response to the air strikes, particularly around Mt Sinjar, where on Saturday US warplanes attacked Isis positions surrounding the mountain where tens of thousands of Iraqi Yazidis have taken a tenuous refuge.
(14) In the years since the housing market bottomed out, Tremont and other pockets of Cleveland have witnessed a tenuous revitalisation thanks to newcomers seeking city lifestyles and new investment in 21st-century industry.
(15) Although the bright green light helped counteract sleepiness, any causal link with changes in melatonin output seem tenuous.
(16) America's arch enemy, Muammar Gaddafi, had thousands of troops camped in the remote desert of northern Chad, a forward front in his pan-African expansionist plan, but a thousand miles from Tripoli on tenuous supply lines and thus highly vulnerable.
(17) Data indicate that non-rehospitalization is associated with a stance of "positive withdrawal" (Corin 1990); it is characterized by a position at a distance from social roles and social relationships, combined with various strategies for keeping more tenuous links with the social environment.
(18) However, their entry into force was delayed for a "few days" according to a statement from Brussels, to leave time to assess the implementation of a tenuous ceasefire agreement in Ukraine negotiated last Friday.
(19) Although these results suggest a tenuous relationship between scrapie pathology and the integrity of neurotransmitter systems, it is possible that compensatory neurochemical changes in uncompromised neuronal populations may have masked potentially specific neurotransmitter effects.
(20) Mair’s links with far-right groups in the US and South Africa are well documented, but his associations with similar organisations closer to home appear more tenuous.