(n.) That which underlies all outward manifestations; substratum; the permanent subject or cause of phenomena, whether material or spiritual; that in which properties inhere; that which is real, in distinction from that which is apparent; the abiding part of any existence, in distinction from any accident; that which constitutes anything what it is; real or existing essence.
(n.) The most important element in any existence; the characteristic and essential components of anything; the main part; essential import; purport.
(n.) Body; matter; material of which a thing is made; hence, substantiality; solidity; firmness; as, the substance of which a garment is made; some textile fabrics have little substance.
(n.) Material possessions; estate; property; resources.
(n.) Same as Hypostasis, 2.
(v. t.) To furnish or endow with substance; to supply property to; to make rich.
Example Sentences:
(1) No differences between the two substances were observed with respect to side effects and general tolerability.
(2) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(3) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
(4) Intracellular localization of the labeled substance in the tumor tissue was examined autohistoradiographically.
(5) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(6) A substance with a chromatographic mobility of Rf = 0.8 on TLC plates having an intact phosphorylcholine head group was also formed but has not yet been identified.
(7) Serum pepsinogen 1, serum gastrin, ABO blood groups, secretor status of ABH blood group substances and behavioral factors were studied in 15 patients with duodenal ulcer and 61 their relatives affected and unaffected to duodenal ulcer.
(8) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.
(9) Urine tests in six patients with other kidney diseases and with uraemia and in seven healthy persons did not show this substance.
(10) Substance P, a potent vasodilating peptide, seems to be released from trigeminal nerve endings in response to nervous stimulation and is involved in the transmission of painful stimuli within the periphery.
(11) Regulators concerned about physician behavior and confronted by demands of nonphysicians to prescribe controlled substances may find EDT a good solution.
(12) These results are discussed in the light of the mode of action of the substances used.
(13) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(14) We have investigated some of the factors which affect the retention times of these substances in reversed-phase HPLC on columns of 5-micron octadecylsilyl silica.
(15) The data indicate that adult neurons with an intrinsic ability to regenerate axons can respond to substances with neurotrophic or neurite-promoting activities in tissue cultures.
(16) The authors describe the role played by these substances in the pathogenesis of inflammations, their importance in the regulation of intraocular pressure and in the development of cystoid macular oedema.
(17) They were more irregularly curved and consisted of various substances.
(18) We examined 10 life areas clustered around the general categories of "substance use," "social functioning," and "emotional and interpersonal functioning."
(19) In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis.
(20) The following possible explanations were discussed: a) the tested psychotropic drugs block prostaglandin receptors in the stomach; b) the test substances react with prostaglandin in the nutritive solution; c) the substances stimulate metabolic processes in the stomach wall that break down prostaglandin.
Vain
Definition:
(superl.) Having no real substance, value, or importance; empty; void; worthless; unsatisfying.
(superl.) Destitute of forge or efficacy; effecting no purpose; fruitless; ineffectual; as, vain toil; a vain attempt.
(superl.) Proud of petty things, or of trifling attainments; having a high opinion of one's own accomplishments with slight reason; conceited; puffed up; inflated.
(superl.) Showy; ostentatious.
(n.) Vanity; emptiness; -- now used only in the phrase in vain.
Example Sentences:
(1) For example, if we purchase new examination equipment without any consideration or if we decide what type of equipment to introduce according to the common advice of the purchase committee of the hospital or the medical school, then we cannot design an ideal system of laboratory examinations and are forced to invest a large sum of money in vain.
(2) The George Bush campaign juggernaut hit the first serious pothole of its cash-fuelled drive to the presidency yesterday, as the Texas governor tried in vain to fend off questions about whether he had used cocaine as a young man.
(3) Full set list, show one (thanks to princevault.com ) Take Me With U (acoustic) Raspberry Beret (acoustic) U Got The Look (acoustic) Instrumental jam (acoustic) Train In Vain (acoustic) Q & A (1) incl.
(4) VaIN rarely is an isolated lesion and frequently is preceded by, or coexists with, other types of premalignant genital squamous neoplasia.
(5) He’s the kind of self-styled intellectual journalist in politics who caused so much trouble in 20th century politics, not a bad man, decent enough in his way, but not as smart as he thinks he is, vain with it.
(6) For long spells, West Ham searched in vain for inspiration as they tried to find a way past Newcastle United’s defence and end a run of three matches without a win.
(7) Further, in a vain attempt for a boost in the Hoosier State, Cruz unveiled former rival Carly Fiorina as his running mate if he receives the nomination and was able to cajole the state’s sitting governor, Mike Pence, into an endorsement.
(8) The next few days may well determine whether, this time, such loyalty will be in vain; but, while yearning for a clarion call and what was described as "vision" in this paper's leading article yesterday, I need to pose some pretty stark questions to Guardian readers.
(9) He aims to put his newspapers, including the Times and the Sun, behind a paywall, something described by the co-founder of Twitter, Biz Stone, as a vain attempt to "put the genie back in the bottle".
(10) In vain I argued that Robin Day seemed to wear the same jacket and shirt every week, and fled back to radio."
(11) Now I can feel that my son's blood wasn't totally lost in vain.
(12) In vain will Cameron plead that blame should lie with Brown and his Labour colleagues.
(13) At a media day held to mark the completion of the training and arranged before the tragedy, soldier after soldier came forward to insist that, though they were apprehensive, they were determined to do a good job, partly to make sure that their six colleagues had not died in vain.
(14) He somehow scrambled to deuce and delighted in forcing Dimitrov to chase in vain from one side of the court to the other to go 6-5 up.
(15) Assessment of patients between 9 and 99 (mean 55) months after partial colpectomy for VAIN showed no recurrence of disease in ten patients (83%).
(16) The scientific establishment struggled in vain to produce evidence that would reassure the public.
(17) No grieving wants to go through that, and our city doesn’t want to go through that.” Murphy said an accelerated program to equip Baltimore police officers with body cameras would mean Gray “did not die in vain”.
(18) His mother has said she tried in vain to get help for him.
(19) But he flailed in vain as the police officers grabbed him, one forcing his T-shirt roughly up over his head as three or four others laid in with their wooden batons, dragging and pushing him to a line of waiting Land Cruisers and more helmeted cops.
(20) As Steve spends half his money trying in vain to keep a scowl off Michelle's face and the rest comfort eating, Liz stumped up half the cash.