What's the difference between sulphine and sulphone?

Sulphine


Definition:

  • (n.) Any one of a series of basic compounds which consist essentially of sulphur united with hydrocarbon radicals. In general they are oily or crystalline deliquescent substances having a peculiar odor; as, trimethyl sulphine, (CH3)3S.OH. Cf. Sulphonium.

Example Sentences:

  • (1) In contrast, in the majority of neurones, responses to glutamate, aspartate, cysteate and cysteine sulphinate demonstrated a conventional voltage relation, were associated with a decrease in membrane resistance, evoked no slow spikes, were insensitive to extracellular Mg2+ concentrations between 1 and near 0 mM and could be evoked with small currents of amino acids when the electrophoretic pipette was greater than 100 micron from the cell soma.
  • (2) The binding constants, quentum yield and temperature dependence of the fluorescence of ionic (1-anilinonaphtalin-8-sulphinate) and neutral (N-phenyl-1-naphtylamine) probes were studied on the molecules of bovine serum albumine with the change of pH and solution ionic strength.
  • (3) Endogenous amino acids known to activate NMDA receptors (L-glutamate, L-aspartate, L-cysteine sulphinate and quinolinate) as well as exogenous NMDA agonists such as ibotenate and trans-2,3-piperidine dicarboxylate (trans-PDA) all produced similar responses.
  • (4) The progress of the reaction is described and the activities of related sulphinic acids were determined.
  • (5) An oxidative pathway for cysteine catabolism in H. diminuta was shown by the presence of cysteine dioxygenase and cysteine sulphinate transaminase.
  • (6) The recombinant enzyme and the authentic AspATSs are indistinguishable: in fact, they have the same molecular weight, estimated by means of SDS-PAGE and gel filtration, the same Km values for 2-oxo-glutarate and cysteine sulphinate and the same UV-visible spectra.
  • (7) Depletion of GSH by NDPO2 is accompanied by the formation of its disulphide, sulphinate, sulphonate, sulphoxide and other products.
  • (8) The effects of the sulphur containing amino acids, homocysteic acid, homocysteine sulphinic acid, cysteic acid and cysteine sulphinic acid on the release of [3H]-acetylcholine ([3H]-ACh) from the cholinergic amacrine cells of the rabbit retina were examined.
  • (9) The transport kinetics of the excitatory sulphur-containing amino acid (SAA) transmitter candidates, L-cysteine sulphinate (L-CSA), L-cysteate (L-CA), L-homocysteine sulphinate (L-HCSA), and L-homocysteate (L-HCA), together with their plasma membrane carrier specificity, was studied in cerebrocortical synaptosome fractions by a sensitive high performance liquid chromatographic assay.
  • (10) Methanesulphenic acid is proposed to be the group displaced by GSH from methyl sulphoxides forming methyl mercaptan, methyl glutathionyl disulphide and methane-sulphinic acid in vitro.
  • (11) Methane sulphinic acid was quantified by use of a simple colorimetric assay and used to determine the amounts of HO.
  • (12) Except for homocysteine sulphinic acid these actions occurred at concentrations that did not affect the erg b-wave amplitude, indicating a site of action at the inner retina.
  • (13) These results suggest that aspartate, glycine, homocysteic acid, and cysteine sulphinic acid play a role in synaptic transmission in the Schaffer collateral-commissural fibres, and that cysteine sulphinic acid and homocysteic acid may be released specifically by high-frequency stimulation.
  • (14) In general, inhibition: (i) was markedly stereospecific in favor of the L-enantiomers (except for cysteine sulphinate) and (ii) was found to decrease with increasing chain length.
  • (15) Also by automated ion-exchange chromatography seleninic derivatives are well separated from the analogous sulphinic compounds, while selenonic compounds are eluted together with the corresponding sulphonic compounds.
  • (16) Of the four extraction media examined, TCA in combination with ether extraction was shown to be the most potent oxidative treatment and resulted in 23% oxidation of original cysteine or homocysteine to sulphinic and sulphonic acids.
  • (17) Four minutes of continuous 50 Hz stimulation produced a tetrodotoxin-sensitive release of aspartate and glycine in the second minute of stimulation, as well as a tetrodotoxin-sensitive release of cysteine sulphinic acid, during stimulation and of homocysteic acid, following stimulation.
  • (18) The neuroactive sulphur-containing amino acids L-cysteate (CA), L-cysteine sulphinate (CSA), L-homocysteine sulphinate (HSA), S-sulpho-L-cysteine (SC) and L-homocysteate (HCA) evoked the release of previously accumulated D-[3H]aspartate from rat brain cerebrocortical and cerebellar synaptosome fractions in a manner that was wholly Ca2+-independent.
  • (19) Metabolically formed nitrosoarenes react with sulphydryl groups of haemoglobin and, after intramolecular rearrangement, yield sulphinic acid amides.
  • (20) 3) In contrast the cysteic and cysteine sulphinate decarboxylase activities decrease with age in kidney, lung and spleen.

Sulphone


Definition:

  • (n.) Any one of a series of compounds analogous to the ketones, and consisting of the sulphuryl group united with two hydrocarbon radicals; as, dimethyl sulphone, (CH/)/.SO/.

Example Sentences:

  • (1) The PSB dioxygenase system displayed a narrow substrate range: none of 18 sulphonated or non-sulphonated analogues of PSB showed significant substrate-dependent O2 uptake.
  • (2) They disappear after Leydig cell depletion induced by ethanedimethane sulphonate (EDS) and return after testosterone treatment.
  • (3) Treatment with sulphones, in combination with cortico-steroids in the more severe cases, has resulted in long-term improvement in two of our three patients.
  • (4) In anaerobiosis, at 25 mM sulphanilic acid, or with addition of p-toluene sulphonic acid only one regression line is obtained for the permeation in both directions.
  • (5) Isoeugenol fails to elicit a sensitisation response when challenged onto guinea pigs sensitised to methyl dodecane sulphonate, indicating that the mechanism of isoeugenol sensitisation is not based on methyl transfer.
  • (6) Sulphonic-acid derivatives of established carcinogens are usually inactive.
  • (7) The fluorescence of 8-anilinonaphthalene-1-sulphonate is affected both by delta psi and delta pH.
  • (8) Among the sulphonated dyes, amphiphilic mono- and disulphonated derivatives exhibit particularly good cell membrane-penetrating properties, although the more highly sulphonated dyes show better tumour retention in vivo.
  • (9) The chemical asymmetry of the transporter was investigated by studying the effects of p-chloromercuriphenyl sulphonate (PCMBS) on uridine transport and high-affinity NBMPR binding in inside-out and right-side-out membrane vesicles, unsealed erythrocyte ghosts and intact cells.
  • (10) A number of substituted diphenylsulfides and sulfones (4-11) and 2,2'-disubstituted-5,5'-dibenzimidazolyl sulfides and sulphones (12-19) have been synthesized starting from 5-chloro-2-nitroacetanilide and (3) 4,4'-dichlorodiphenyl sulfone (9), respectively.
  • (11) The ryanodine receptor protein of sheep cardiac muscle sarcoplasmic reticulum membranes functions as a ligand-regulated ion channel following solubilization with the zwitterionic detergent CHAPS (3-[(3-cholamidopropyl)-dimethylammonio]-1- propane sulphonate); purification by density gradient centrifugation, reconstitution into proteo-liposomes and incorporation into planar phospholipid bilayers.
  • (12) This involves formation of a mercaptopropyl bonded phase followed by oxidation to the corresponding sulphonic acid.
  • (13) The results indicated that certain sulphonic acid dyes increase the permeability of the respiratory tract epithelium, perhaps by increasing its porosity.
  • (14) T-suppressor-inducer and T-suppressor-effector hybridoma supernatants both regulating the DTH reaction intensity triggered by trinitrophenyl-sulphonic acid (TNPSA) or antigen-dependent proliferation of mice lymph node cells to trinitrophenylated bovine serum albumin, possess and ability to inhibit proliferation of TNPSA-modified human and mice leukaemic cells.
  • (15) Replacement of Cl with Br enhanced the negative afterpotential and and replacement with benzene sulphonate or isethionate depressed it.
  • (16) There was no evidence that the sulphonic group of Tobias acid is cleaved in the body to a significant extent to give 2-naphthylamine.
  • (17) Synergy was commonly observed when the sulphones were combined with ampicillin or amoxicillin, generally reducing the drug minimum inhibitory concentrations (MICs) fourfold to eightfold (synergy rates 85-91%).
  • (18) Plasma and urine concentrations of NTB, albendazole (ABZ), albendazole sulphoxide (ABZSO) and albendazole sulphone (ABZSO2) were measured serially over a 120-h period by HPLC.
  • (19) The effects of MDL 73005EF (8-[2-(2,3-dihydro-1,4-benzodioxin-2-yl)methylamino]-8- azaspiro[4,5]decan-7,9-dione methyl sulphonate), a novel selective 5-HT1A receptor ligand with putative anxiolytic properties, were explored using models of central pre- and postsynaptic 5-HT1A receptor function in the male rat.
  • (20) Responses of neurones to either physiological stimulation of hair and vibrissa follicle sensory afferents and to ionophoretically applied excitatory amino acids were challenged with the antagonists D-2-amino-5-phosphonovalerate (APV), kynurenate and gamma-D-glutamylaminomethyl sulphonate (GAMS).

Words possibly related to "sulphine"

Words possibly related to "sulphone"